Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The late complications of corneo-scleral wound healing after the 15th postoperative day were recorded in 108 routine adult cataract operations using 7-0 polyglycolic acid (Dexon) sutures and compared with 80 routine adult cataract operations using 9-0 monofilament nylon (9-10 Ethilon Nylon) sutures. In 37 eyes of the 7-0 Dexon group filtrating blebs, gaping of the corneoscleral wound, anterior chamber collapse, or decrease in the intraocular pressure were observed compared with one filtrating bleb in the 9-0 nylon group. The majority of late complications occurred 22 to 42 days after surgery. Ten filtrating blebs remained after a 5 months' follow-up period. The most probable cause of the late complications in corneo-scleral wound healing was discussed.
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PMID:Late complications of 7-0 polyglycolic (Dexon) sutures in cataract surgery. 41 74

An improved synthetic absorbable suture for ophthalmic surgery, 8-0 Dexon "S" polyglycolic acid, was evaluated in 25 cataract extractions and, in 5 cases, compared with 8-0 Vicryl polyglactin sutures. Dexon "S" sutures caused less tissue drag than Vicryl sutures; Vicryl was more easily knotted. With respect to handling, knotting, tissue drag, absorption, and postoperative complications, the improved Dexon suture was found to be well suited for use in cataract surgery.
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PMID:Evaluation of an improved suture for cataract surgery. 43 45

This study describes the operative and postoperative performance of 8-0 polyglycolic acid braided suture, trademarked Dexon "s", in cataract surgery. The evaluation consists of a clinical comparison of 8-0 Dexon to the same suture in 7-0 size in 109 cataract surgical procedures. The 8-0 Dexon, like 7-0, gave high tensile strength, good knot security, batch-to-batch uniformity, relatively good pliability, and provoked minimal reaction while disappearing at a predictable rate of around 35 days. When compared to 7-0 Dexon, 8-0 produced less tissue drag, fibrillation, and reaction, while providing better pliability. However, the smaller suture possessed less tensile strength, and had an increased tendency to cut through tissue when tied too tightly.
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PMID:An evaluation of 8-0 polyglycolic acid braided synthetic absorbable suture in cataract surgery. 49 89

Dexon was used as suture material in 26 cases of cataract surgery and in 46 cases of extraocular muscle surgery. It is better than chromic catgut in muscle surgery, since it produces less conjunctival irritation and no granulomas. In cataract surgery, on the contrary, it causes a pronounced irritation of the anterior segment and rather ofter a severe uveitis, probably because the sutures are external.
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PMID:Polyglycolic acid sutures in cataract and extraocular muscle surgery. 63 55

The tissue reaction, absorption, and handling properties of Dexon synthetic absorbable sutures, which are made from polymerized hydroxyacetic acid, were compared with those of silk and collagen in 51 eye operations, consisting mainly of cataract extractions and squint corrections. There was no significant difference between the sutures as regards degree of tissue reaction. The Dexon sutures were very strong and the knots held well. The sizes used in this series were found to be a little too thick and stiff for use in micro-surgery; smaller sizes would be easier to use and still remain strong enough. The Dexon was reliably absorbed in 5 weeks on average. No serious adverse reactions were seen with any of the sutures. Dexon was as well tolerated as the control sutures but had the advantage over silk of being absorbed and over collagen of containing no foreign protein.
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PMID:Comparative trial of Dexon (polyglycolic acid), collagen, and silk sutures in ophthalmic surgery. 76 26

Polyglycolic acid sutures were used in 239 cases of intraocular surgery (164,6-0 size, 75, 7-0 size). Most of these (226) were cataract extractions. The results were excellent, with minimal complications. The 6-0 suture was somewhat stiff and associated with some tissue drag. The 7-0 size overcame these deficiencies and was considered the closest approach to date to the ideal absorbable suture. In addition, these appears to be an inhibition to bacterial penetration by PGA.
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PMID:Further use of polyglycolic acid (Dexon) sutures in cataract and other intraocular surgery. 111 10

6-0 Dexon (polyglycolic acid-PGA) suture was used in 30 eyes of 25 patients in surgical procedures which included cataract extraction, strabismus surgery, and ocular plastic surgery. The suture was found to hold the wound firmly, was not absorbed prematurely, was absorbed completely at a predicted time, was relatively easy to use although the knots were large, did not cause any infection or undue tissue reaction, and did not result in any wound dehiscence or vitreous loss.
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PMID:Evaluation of Dexon suture in ophthalmic surgery. 114 1

The use of 7-0 polyglycolic acid (Dexon) sutures in 200 consecutive outpatient cataract extractions is described and compared with the use of 7-0 chromic gut sutures in 200 consecutive outpatient cataract extractions. The polyglycolic acid sutures appeared to be more comfortable to the patient than the chromic gut sutures, they absorbed at a constant, steady rate compared to a variable rate for the gut sutures and there were less postoperative complications with the polyglycolic acid sutures than with the gut sutures.
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PMID:The use of polyglycolic acid sutures in outpatient cataract surgery. 126 10

The results of 64 operations of cataract in dogs applying the operating microscope are presented in the paper. The dogs were divided into 4 groups according to the type of cataract: senile, symptomatic, diabetic and toxic. The lenses were removed with a ++cryo-extractor , Dexon and Vicryl were used for suturing. The evaluation of dogs' ability to see after cataract surgery was made on the basis of clinical examinations of vision, ophthalmoscopy and clinical tests. The results of microsurgical cryoextraction in dogs were positive as far as senile and symptomatic cataracts were concerned. No positive results were obtained in the case of diabetic cataract because of existing retinopathy and in toxic cataract where retinal atrophy caused by intoxication occurred. Cataract surgery does not lead to a complete return of vision since the eye is aphakic and hypermetropic. However, it permits the dog to use its sense of vision for orientation in the environment.
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PMID:Clinical value of microsurgical cataract surgery in dogs by cryoextraction method. 213 47

In 115 consecutive cataract extractions with implantation of artificial lens a clinical evaluation of absorbable sutures--polyglactin (910) (Vicryl 7-0) and polyglycolic acid (Dexon 8-0)--in corneolimbal incision has been performed. The corneolimbal wounds were closed by continuous suture technique with one double loop knot at the 12 o'clock and 5-6 loops on each side of the 12 o'clock knot. The suture had disappeared after 8 weeks in 95% of the eyes. Two months after operation the visual acuity, the power of corneal astigmatism and astigmatic orientation remained unchanged in both the Vicryl and the Dexon sutured group. This provided effectuation of early full prescription of glasses. Most complications in this material were suture independent and appeared during the early postoperative period. In only one eye inadequate wound closure was noticed. Shallow anterior chamber and hypotonia of short duration occurred in 5 eyes. Four of these patients developed corneal dystrophy. In the Vicryl sutured group suture reactions took place in 87% of the eyes. With dexon suture no such reaction appeared. The use of absorbable sutures in corneolimbal incision technique implies several surgical advantages and is seemingly safe.
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PMID:Absorbable sutures (Dexon and Vicryl) in the corneolimbal incision. Used in lens implantation surgery. 625 Mar 15


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