Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study is based on a detailed investigation of 12 cases of Irvine-Gass syndrome which was observed during the examination of 350 patients operated for pathological or senile cataract. The authors have found that: Males were affected more than females. Arteriol hypertension increases the frequency of the disease. The syndrome was found at an increase frequency in cases of nuclear cataract and in case where cataract was extracted by cryo-extraction. The bulge of the vitreous within the anterior chamber (without rupture of the anterior hyaloid membrane) causes a higher frequency of the disease. A similar observation was made when there was an incarceration of the vitreous to the surgical wound. The retreat of the edema was faster when the syndrome appeared earlier than the cataract operation. Whereas the restoration of good visual acuity did not depend upon the time of appearance of the disease. During the fluorescein study the following was observed. The possible participation of the chorio-capillaris layer in the pathogenicity of the disease. The diffusion of the fluorescein diminished with the improvement of the disease. Fluorescein angiography is unquestionably superior to simple ophthalmoscopy or the coloured photograph of the fundus of the eye, because the full extent of the existing damage can be revealed only through this method.
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PMID:[Irvine-Gass syndrome. Statistical and angiographic study]. 13 33

Fluorescein angiograms were performed in 90 patients the first and sixth week after removal of non-traumatic cataracts by phacoemulsification. The incidence of macular edema was found to be one half that reported in the literature for a comparable group of patients following intracapsular cataract extraction. The difference in incidence of macular edema between the phacoemulsification and the intracapsular groups seems dependent on the presence of the posterior capsule and perhaps the small size of the phacoincision. One of 21 maculas with angiographic evidence of edema developed clinical cystoid macular edema.
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PMID:Incidence of fluorescein angiographic subclinical macular edema following phacoemulsification of senile cataracts. 55 28

Thirteen years after cataract extraction, a patient complained of diminished visual acuity. In the interim visual acuity was 6/6 (20/20), or 6/7.5 (20/25+2). Fluorescein angiography demonstrated cystoid macular edema. Except for vitreous adherence to the inner surface of the cataract wound, no ocular cause for the macular edema was apparent.
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PMID:Cystoid macular edema occurring 13 years after cataract extraction. 86 51

A 71-year-old woman complained of "smoky" vision, which was found to be caused by a hyphema with blood dripping from a vascular tuft located in the 12 o'clock meridian of the iris. Fluorescein angiography delineated vascular tufts and argon laser photocoagulation eradicated one of the tufts that bled. Histopathologic studies of iris obtained at the time of cataract extraction showed an aggregate of small vessels at the pupillary margin. Most patients with vascular tufts of the pupillary margin have no systemic disease but they are also observed in diabetes mellitus and myotonic dystrophy.
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PMID:Vascular tufts of pupillary margin of iris. 86 91

A woman developed an inner lamellar macular hole and cellophane maculopathy as a complication of chronic cystoid macular edema following cataract extraction. Fluorescein angiography revealed a cystoid pattern of fluorescence in the paracentral area but no evidence of staining in the region of the hole. Following death, histopathologic examination of both eyes confirmed the clinical observations. Biomicroscopic examination and fluorescein angiography are of value in differentiating an inner lamellar macular hole from a full-thickness macular hole and from a pseudomacular hole caused by spontaneous contraction of an epiretinal membrane.
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PMID:Lamellar macular hole: a complication of cystoid macular edema after cataract extraction. 126 56

Fluorescein angiography was safely performed in 100 consecutive cases of cataract extraction during the first postoperative week. Seventy-five percent of the 100 eyes had good quality fluorescein angiograms. Four eyes demonstrated cystoid macular edema. Therefore, the incidence of cystoid macular edema in the first week after cataract surgery was low when compared to the reported incidence (40%) four to six weeks postoperatively.
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PMID:Cystoid macular edema in the first week after cataract extraction. 127 40

Fluorescein leakage into the anterior chamber (AC) and from the iris were found early after extracapsular cataract extraction (8 eyes) and IOL implantation (29 eyes). The leakage into AC and from the iris were apparently comparable after ECCE, whereas the former was stronger after anterior or posterior chamber IOL implantation, and no leakage was discernible where the iris and the loops of AC-IOL were in contact. Fluorescein leakage into the AC and from the iris indicated overall traumatic damage to the blood-aqueous barrier.
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PMID:[Anterior segment fluorescein angiography and IOL implantation]. 129 84

Fluorescein movements in the lens laminae of isolated porcine eyes were examined by biomicroscopy. The stain disseminated in two directions: from the lens nucleus to capsules and fluorescein release into the intraocular fluid and from the outer laminae of the equatorial zone to the nucleus. Lecozyme, a proteolytic agent, accelerated fluorescein movement in both directions. The method suggested by the authors permits an objective assessment of fluorescein movement in the lens, which appears to reflect the processes of extracellular fluid ultrafiltration in the lens. The data evidence the possibility of effecting the extracellular intralenticular fluid microcirculation by proteolytic enzymes. The suggested technique may be useful in studies of cataract pathogenesis and of anticataract action of various drugs.
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PMID:[Fluorescein movement in a transparent lens]. 223 28

Mussel adhesive protein (MAP) is a new tissue adhesive derived from the sea mussel Mytilus edulis. Rabbit eyes were injected intravitreally with 1 mg of MAP or balanced salt solution in order to determine the intraocular effects of this new biologic tissue adhesive. Two concentrations of MAP were used: one was undiluted and the other was diluted to a concentration of 1:10. A marked cellular inflammatory response, compared with the control eyes, was seen clinically in the vitreous cavity of animals in which MAP was used undiluted. This response persisted for up to two weeks and was suggestive of inflammatory response to a foreign protein. When MAP was used at a dilution of 1:10, a mild transient cellular reaction was observed in the vitreous; this cleared after seven days. There was no increase in intraocular pressure, and none of the eyes developed cataract or optic nerve damage. Fluorescein angiography demonstrated no vascular leakage and electroretinography was normal in all of the eyes at two weeks. Histopathologic evaluation of the eyes at 7 and 14 days after injection revealed localized cellular inflammation in the vitreous and adjacent retina when MAP was used undiluted, but no reaction in the control eyes or in eyes injected with MAP at 1:10 dilution. This preliminary study suggests that MAP produces a marked intraocular inflammatory reaction when used at full concentration. By diluting the adhesive, a less severe inflammatory response was observed, which cleared with no complications.
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PMID:Intravitreal biocompatibility of mussel adhesive protein. A preliminary study. 240 56

We compared the incidence of angiographic cystoid macular edema (CME) in eyes with ultraviolet (UV)-absorbing intraocular lenses (IOLs) with that in eyes with non-UV-absorbing IOLs. Fifty-five bilateral pseudophakic patients received a UV-absorbing IOL in one eye and a non-UV-absorbing IOL in the fellow eye. All cases were implanted with posterior chamber lenses following extracapsular cataract extraction. Fluorescein angiography for CME was performed at least six months postoperatively (average 20.0 months). There was no statistically significant difference in visual acuity or in the incidence of CME.
J Cataract Refract Surg 1989 Nov
PMID:Ultraviolet-absorbing intraocular lens versus non-UV-absorbing intraocular lens: comparison of angiographic cystoid macular edema. 261 8


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