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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of infectious endophthalmitis caused by the saprophyte Exophiala werneckii is reported. This has not been recognized as a pathogen for ocular infections previously. The infection followed uncomplicated cataract surgery involving phacoemulsification and IOL implant. Clinical presentation was that of an indolent endophthalmitis with relatively acute onset. Pars plana vitrectomy, fungal stains, and culture established the diagnosis. Initial management consisted of empirical intravitreal injection of vancomycin, ceftazidime, and amphotericin B. Treatment was supplemented with a 3-week course of systemic fluconazole and topical therapy with natamycin, atropine, ciprofloxacin, and diclofenac. The visual acuity returned to 20/20-2 with no recurrence of infection. The source of the infection could not be determined. Fungal endophthalmitis has to be considered as a rare, though important, complication following ophthalmic surgery. Specific fungal stains and cultures are helpful for establishing the diagnosis early in the course of disease. E werneckii should be considered in the differential diagnosis of fungal endophthalmitis.
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PMID:Exophiala werneckii endophthalmitis following cartaract surgery in an immunocompetent individual. 1101 11

A healthy 76-year-old woman complained of redness and a painful sensation in her right eye after cataract surgery 5 months previously. The eye was treated with topical corticosteroid and ciprofloxacin, and a soft exudative mass on the nasal lower iris was noted later. Fungal endophthalmitis was suspected and a repeat aqueous culture grew Penicillium spp. After treatment with topical natamycin and an intracameral injection of amphotericin B, the endophthalmitis was cured. We describe the disease course and management and discuss topical corticosteroids as a possible risk factor for increasing the dissemination of Penicillium infection. This was a unique case of successful therapy resulting in the cure of Penicillium endophthalmitis in an immunocompetent patient.
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PMID:Pseudophakic Penicillium endophthalmitis. 1107 35

A 20-year-old man developed increasing inflammation with a hypopyon 3 weeks after primary repair of a corneal laceration. An occult anterior capsule puncture was suspected as the stimulus for the inflammation. When aspiration of the suspected hydrated lens material was not curative, a vitrectomy with injection of intravitreal antibiotic agents including amphotericin (0.0125 mg) was done the following day; the culture failed to grow fungal organisms. A repeat vitrectomy was performed 1 week later, and the culture grew Aspergillus terreus. This was determined to be resistant to amphotericin so voriconazole was injected intravitreally. The inflammation recurred, and the eye required enucleation because of blindness and intractable pain. Fungal endophthalmitis should be considered in cases of delayed-onset inflammation after trauma and may be due to organisms resistant to amphotericin.
J Cataract Refract Surg 2007 Apr
PMID:Posttraumatic Aspergillus terreus endophthalmitis masquerading as dispersed lens fragments. 1739 54

Fungal endophthalmitis is a destructive intraocular infection resulting in poor visual prognosis. Endophthalmitis due to Fusarium spp has the worst visual prognosis. We report a case of a 58-year-old female patient who underwent cataract extraction and intraocular lens implantation in the right eye and presented two months after the surgery with fungal endophthalmitis. The aqueous humor culture grew Fusarium dimerum. The patient was treated with intravitreal and oral voriconazole and topical prednisolone. The patient experienced one episode of recurrence following by remarkable improvement. To our knowledge, this is the first reported case of Fusarium dimerum endophthalmitis.
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PMID:Post-operative endophthalmitis due to Fusarium dimerum. 2341 13

Fungal endophthalmitis is a rare complication after cataract surgery and is associated with significant morbidity including vision loss. The common causative fungal pathogens implicated in fungal endophthalmitis after cataract surgery include Candida species (spp.) and molds such as Aspergillus spp. and Fusarium spp. Early diagnosis and effective antifungal treatment after a high index of clinical suspicion are required to reduce unfavorable complications and to preserve eye function. This review discusses epidemiology, pathogenesis, clinical features, diagnosis, management, and outcomes associated with fungal endophthalmitis after cataract surgery.
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PMID:Risk of Fungal Endophthalmitis Associated with Cataract Surgery: A Mini-Review. 2631 95