Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Angle-closure glaucoma is a severe disease that may lead to loss of eyesight. We report a case of an 80-year-old woman diagnosed as left angle-closure glaucoma just before the emergency ileus operation. Before the operation, pilocarpine eye drop was given for the left eye and laser-iridotomy for the right eye was performed, with mannitol given as indicated by the ophthalmologist. After the operation, eye drop was administered to both eyes until she left the surgical ward 20 days after the operation. Three days after the operation the patient had another attack and mannitol was given again. The cause of the attacks was unclear, but the treatment was effective and the patient showed a good recovery. Twenty six days after the operation, the patient was admitted to the ophthalmic ward and underwent extracapsular extraction of the senile cataract of the left eye, which was also a treatment for the glaucoma. Anatomical structure of the eye, changes in environment, medicine, and anesthetic maneuvers have effects on the eye pressure. In addition to efforts to prevent the attack, quick discovery and adequate treatment are important for angle-closure glaucoma.
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PMID:[A case of angle closure glaucoma attack treated during perioperative period of emergency ileus operation]. 1602 65

Congenital chloride diarrhoea (CCD) is a serious inherited defect of intestinal electrolyte absorption transmitted in an autosomal recessive way. The molecular pathology involves an epithelial Cl(-)/HCO(3)(-) exchanger protein, encoded by the solute carrier family 26 member 3 gene (SLC26A3) and known DRA (down regulated in adenomas) in the distal ileum and colon. Polyhydramnios, premature birth, ileus without meconium passage, hypochloremia, and hyponatremia are typical features of CCD in the neonate followed by chronic metabolic alkalosis, hypokalemia, hypochloremia, retarded growth and renal impairment in older children and adults if the disease is not adequately treated. Antenatal diagnosis if made on the basis of findings on ultrasonography-a non-invasive diagnostic test-can help in early management of the disorder immediately after birth and, thus, prevent the sequelae. We present an interesting case of CCD diagnosed antenatally and found to have congenital cataract, which is a unique occurrence not reported in literature so far.
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PMID:Congenital cataract and congenital chloride diarrhoea-a unique combination and antenatal diagnosis. 2184 17