Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Aphakic cystoid macular edema (ACME) can be a visually significant complication of modern cataract surgery. Prophylaxis of ACME is preferable to therapy of established ACME. Selection of the appropriate cataract operation, control of systemic factors, avoidance of topical catecholamines, control of intraocular inflammation and use of topical or systemic pharmacologic agents may play a role in the prevention of ACME. If it is proven that light toxicity influences the development of ACME, filters in operating microscopes or in intraocular lenses, cataract glasses, or contact lenses may be helpful. Once ACME is present, antiinflammatory therapy has been the main intervention, although its longterm value remains uncertain. Surgical approaches of unproven value have included photocoagulation, vitrectomy, and removal of an intraocular lens.
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PMID:Prophylaxis and therapy of aphakic cystoid macular edema. 637 51

Aphakic cystoid macular edema (ACME) is a common condition seen after intracapsular cataract extractions. In an overwhelming majority of these cases, the condition improves spontaneously. Those cases that persist for months or years, however, are often associated with vitreous strands adherent to the surgical wound and distortion of the pupil. This article reviews the surgical and photocoagulation therapies for this condition that have been reported over the past two decades. All studies report encouraging results, but all have been nonrandomized, uncontrolled trials. This paper describes two randomized, controlled clinical studies that are attempting to evaluate objectively the role of vitrectomy for chronic cases of aphakic cystoid macular edema.
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PMID:Surgical therapy for chronic aphakic cystoid macular edema. 675

Aphakic cystoid macular edema was demonstrated angiographically in both eyes of the patient, two months after bilateral cataract extraction. The right eye, which suffered a previous temporal branch artery occlusion, demonstrated a distinctive semicircular pattern of edema. No leakage of fluorescein occurred in the region below the horizontal raphe. The case illustrates that aphakic cystoid macular edema is caused by abnormalities in the retinal, rather than the choroidal, vasculature.
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PMID:Aphakic cystoid macular edema after branch artery occlusion. 738 23