Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A vitrectomy was performed in 18 eyes (15 patients) with vitreous hemorrhages due to Terson's syndrome. The average age of the patients was 46.5 +/- 14.4 years. The mean interval between the acute event of an intracranial hemorrhage and the vitrectomy was 6.8 +/- 4.9 months. The vitreous hemorrhage was associated with epiretinal membranes in 3, PVR in 2, and retinal breaks and/or rhegmatogenous retinal detachment in 3 eyes. The vitrectomy had to be combined with membrane peeling in 2, encircling procedures or exoplants in 4, cryotherapy in 5, endolaser in 1, and air/SF6 gas filling in 3 eyes. A missing or incomplete posterior vitreous detachment in 8 eyes was associated with a higher risk of PVR and retinal detachment. Two eyes with this condition needed 3 secondary operations. The mean follow-up duration was 32 (1 to 126) months. Two patients died 4 and 11 months after the operation. The visual acuity improved significantly following vitrectomy in all 18 eyes. The final visual acuity was better than 20/40 in 73% and 20/25 to 20/20 in 56%. The initial postoperative visual acuity decreased later on due to nuclear cataract in 7 of 10 eyes of patients over 45 years of age. A complicated cataract developed in only 1 of 8 eyes of younger patients who maintained a mean visual acuity of 20/25. Vitrectomy for Terson's syndrome is recommended in bilateral cases without spontaneous clearing of the vitreous within 3 months, as well as in cases with PVR and imminent retinal detachment.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Vitrectomy in Terson syndrome. Report of 18 cases]. 161 28

Forty-nine consecutive eyes with nonclearing vitreous hemorrhage not associated with retinal or choroidal vascular disease underwent vitrectomy. Etiologies included vitreous hemorrhage during anterior segment surgery (22 eyes), blunt trauma (8 eyes), retinal tears with and without retinal detachment (8 eyes), Terson's syndrome (2 eyes), avulsed retinal vessel (1 eye), and idiopathic cases (8 eyes). The final visual acuity improved in 48 eyes (98%). Follow-up was 6-91 months (mean, 20 months). Of the 49 eyes, 40 eyes (82%) had a best postoperative visual acuity of 20/100 or better, 31 eyes (63%) had visual acuity of 20/40 or better, and 12 eyes (24%) had visual acuity of 20/20. The major complications included intraoperative iatrogenic retinal breaks (5 eyes), postoperative progressive cataract (7 eyes), late retinal detachment (4 eyes) and recurrent vitreous hemorrhage (2 eyes). The major complication associated with later visual loss was progressive cataract.
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PMID:Vitrectomy for nondiabetic vitreous hemorrhage. Not associated with vascular disease. 342 Mar 16

Retinal periphlebitis appeared as an early sign of bacterial endophthalmitis in three patients, a 36-year-old man with bilateral Terson's syndrome who underwent vitrectomy for dense vitreous hemorrhage, a 78-year-old woman who had had intracapsular cataract extraction and penetrating keratoplasty after repair of a wound leak and pars plana anterior membranectomy, and an 18-year-old man who suffered an accidental penetrating ocular injury. Staphylococcus organisms were recovered from vitreous samples in all three cases. Although recovery of useful vision is rare after postvitrectomy endophthalmitis, the first patient attained a final visual acuity of 20/50. The visual acuities of the second and third patients returned to 20/25 and 20/20 respectively. In an experimental primate (cynomolgus monkey) model of bacterial endophthalmitis, retinal periphlebitis developed early and closely resembled the clinical findings in humans. Histopathologic studies confirmed the presence of inflammatory cells that infiltrated the retinal venules.
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PMID:Retinal periphlebitis as an early sign of bacterial endophthalmitis. 660 67

In a group of 94 eyes with nondiabetic vitreous hemorrhage that underwent pars plana vitrectomy between March 1974 and September 1982, the causes of the hemorrhages were retinal branch vein obstruction (36 eyes), blunt trauma (11 eyes), cataract extraction (ten eyes), subretinal neovascularization (nine eyes), Eales' disease (eight eyes), Terson's syndrome (four eyes), and idiopathic (five eyes) and miscellaneous (11 eyes) conditions. Vision was improved postoperatively in 88 of the 94 eyes, including all of those that underwent blunt trauma or cataract extraction, those with Eales' disease and Terson's syndrome, and those in the idiopathic and miscellaneous groups. Final visual acuities, which depended primarily on the underlying condition and its effect on the macula, were 20/20 or better in ten eyes, 20/25 to 20/40 in 37 eyes, 20/50 to 20/200 in 26 eyes, 20/300 to 20/400 in 11 eyes, 9/200 to 5/200 in three eyes, and hand movements or light perception in seven eyes. Retinal tears, the most common surgical complication, occurred in 18 eyes. The incidence of anterior retinal tears was reduced from 11% (11 of 38 eyes) to 4% (two of 56 eyes) after we began using a vitrectomy probe with a smaller diameter. Some postoperative lens opacification occurred in 16 of 50 phakic eyes, and the incidence of later lens opacification increased as the follow-up lengthened.
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PMID:Vitrectomy for nondiabetic vitreous hemorrhage. 662 34

The syndrome of intra-vitreous bleeding in association with subarachnoid hemorrhage (SAH) was first described by the French ophthalmologist Albert Terson. In the last 10 years, 31 articles describing 202 cases of Terson's syndrome (TS) were published. Only 3 out of the 31 were printed in non-ophthalmological journals. The findings of our prospective study underline the fact that too little attention is paid to TS in the early treatment of patients with SAH. Between 1/95 and 8/97, 89 patients with spontaneous SAH (7% of all admissions) were transferred to our hospital for post acute phase rehabilitation. Out of these, 13 patients (19 eyes) could be diagnosed with TS. This corresponds to an incidence of 14.6% of all patients with SAH (previous studies: 2-27%). However, only one patient had been correctly diagnosed with TS in the referring clinic. Early recognition of TS is of high importance since diminuation of visual acuity even to functional blindness, complicated in the bilateral case, can hamper the rehabilitative process considerably. Moreover, complications can lead to significant and irreversible damage, i.e. proliferative vitreo-retinopathy (PVR), retinal breaks, traction amotio, and cataract. Suspicion of TS is raised in either cooperative patients complaining of compromised visual acuity or in patients where funduscopy shows vitreous opacity. According to our results, visual evoked potentials (VEP) have only a limited role in diagnosis because of their low sensitivity. Not infrequently, however, VEP may point to accompanying optic nerve atrophy, thereby suggesting conservative treatment. Absolute indications for surgical interventions are PVR and its sequelae; relative indications are subjective visual impairment, impediment of rehabilitation, or lack of spontaneous resorption of the hemorrhage. The surgical procedure of choice is the pars plana vitrectomy (PPV). Rare complications of this operation are retinal damage, endophthalmitis, and reoccurrence of hemorrhage.
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PMID:[Terson syndrome: a frequently missed ophthalmologic complication in subarachnoid hemorrhage]. 981 67

The retrospective case review was aimed to demonstrate anatomical and functional results of pars plana vitrectomy (PPV) in patients with Terson's syndrome (TS). The most common cause of TS was an acute subarachnoid hemorrhage of ruptured intracranial aneurysm (6 eyes). One patient suffered traumatic subdural and subarachnoid hemorrhage. PPV was performed in 7 eyes of 6 patients (2 women and 4 men). The patients ranged in age from 18 to 53 years (average 37.5 year), the mean age was 37.5 years. The interval between intracranial hemorrhage and PPV varied from 2 to 12 month (average 7.5 months). The visual acuity postoperatively improved in all 7 eyes. The mean period of observation was 12.5 month. Intraoperative complications included retinal break (1) only. Late complications included epiretinal membrane (2), glaucoma (1), cataract (2) and conjunctival cyst (1). Pars plana vitrectomy is highly effective and relatively safe method in hastening visual rehabilitation of adults with Terson's syndrome.
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PMID:[Terson's syndrome, pars plana vitrectomy and anatomical and functional outcome]. 1598 91