Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eight rhesus monkeys underwent unilateral vitrectomy and subsequent injection of blood into both vitreous cavities. There was no significant inflammation, cataract, delayed corneal healing, or elevated intraocular pressure. Blood in the operated eyes dispersed immediately while blood in the control eyes did not disperse until seven to 14 days after injection. All operated eyes showed more rapid clearing of blood than control eyes containing formed vitreous. This result occurred in the presence or absence of the crystalline lens.
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PMID:Resorption of intravitreal blood following vitrectomy. 82 66

To determine the time relationships between hypotony, choroidal detachment, and shallowing of the anterior chamber, an initial 64 eyes closed with 7-0 black silk were studied with applanation tensions, indirect ophthalmoscopy, and slit lamp examinations before surgery and for six weeks after cataract extraction. Applanation tension less than 6 mm Hg was detected in 72% of eyes, choroidal detachment in 44%, and shallowing of the anterior chamber in 28%. Low intraocular pressure was always detected at the same time or before either choroidal detachment or shallow anterior chamber. The peak period when pressure dropped to less than 6 mm Hg was shortly before 12 to 14 day suture removal or the day after. Suture tract leakage appears to be the predominant mechanism triggering this hypotony. Hypotony is prolonged past the leakage period, probably by ciliary body detachment. This 7-0 silk closure group is compared with 53 eyes closed with 9-0 virgin silk and 45 eyes closed with 9-0 nylon. Both of these latter groups showed substantially lower incidences of hypotony, choroidal detachment, and shallowing of the anterior chamber.
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PMID:Delayed hypotony, shallow anterior chamber, and choroidal detachment in the postoperative cataract eye. A comparative study of closure with 7-0 silk, 9-0 silk, and 9-0 nylon. 87 18

Visual field, acuity, and optic nerve head were evaluated in 24 patients with transient but marked elevations in intraocular pressure. The patient population consisted of 16 patients with angle-closure glaucoma and 7 with high tensions following cataract surgery. In all cases, duration and extent of pressure elevation is documented as well as subsequent visual field, acuity, and fundus examinations. In selected cases, visual field determinations were made during the acute pressure elevation. Previous reports of patients with acute pressure elevation are reviewed. The general absence of glaucomatous field defects in this patient population is discussed with respect to the possible pathogenesis of field loss seen in chronic simple glaucoma.
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PMID:Visual field changes following acute elevation of intraocular pressure. 89 76

The postoperative course of 309 eyes subjected to trabeculectomy has been studied over a 7-year period. The results have been compiled with regard to effectiveness to maintain a normal range of intraocular pressure with and without postoperative medication. The figures have been assessed in toto and for 3 groups of glaucoma, namely, open angle, chronic angle-closure, and acute angle-closure. Results support those of other reports to show that trabeculectomy gives satisfactory control over the years in a reasonably high proportion of eyes and with relatively few postoperative complications. There is also a small group of combined trabeculectomy with cataract extraction.
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PMID:Trabeculectomy: long-term follow-up. 91 34

Tonometric mass screening for industrial nations is not recommended. Amongst the reasons against mass screening is to be emphasized the sufficient prevention of glaucoma blindness, if the reading glasses are prescribed by the ophthalmologist and if he measures the intraocular pressure in each patient over 40 years of age. In developing countries the programmes are completely different since here no medical treatment is possible. The cost benefit calculation is presented for such mass screening, which should be directed to the early recognition of simple glaucoma and which should combine tonometry and Friedman Analyzer field study. Pilot studies should show, whether it is useful or not to include the inspection of the optic disc. Glaucoma teams could be associated with the cataract eye camps. Their work must be coordinated by a center, which evaluades the results of the examination teams and changes directives accordingly.
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PMID:[The early diagnosis of glaucoma as a social medical problem (author's transl)]. 91 8

This study reports on the favourable influence of lens extraction alone on intraocular pressure levels in different kinds of glaucoma (wide angle, angleclosure, secondary). Out of 2000 eyes undergoing cataract surgery 162 had medically treated glaucoma prior to surgery. Follow-up examinations of the intraocular pressure could be carried out in 118 eyes over a year. There resulted from this study no certain indications for a combined operation, whose value is discussed.
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PMID:[Cataract operations and glaucoma - a study (author's transl)]. 92 39

Combined cyclodialysis and cataract extraction was performed on 78 eyes in a consecutive series of 26 years duration. This operation was performed on eyes with severe glaucoma, inadequately controlled on maximum medical therapy, and with a cataract needing extraction. Glaucoma types included open-angle, angle-closure with peripheral anterior synechias, combined open-angle and angle-closure, and secondary to uveitis. Seventy of the 78 eyes had follow-up of six months or more and the results in these 70 eyes were analyzed. In thirteen percent of the eyes in this study the postoperative intraocular pressure was the same or higher than the preoperative level, or reductions of intraocular pressure were not clinically significant. Eighty-seven percent (61 eyes) had a clinically significant lowering of intraocular pressure following the combined procedure. Thirty-nine percent (27 eyes) of the 70 eyes in this study had a tension of 0-14 mm Hg, and 44% (31 eyes) had a tension of 15-20 mm Hg. Intraocular pressure was improved significantly more often in patients over 60 years of age. Resulting intraocular pressures of 14 mm Hg or less were more likely when the cyclodialysis was performed in the lower quadrant. The results of the combined procedure were not significantly influenced by the type of glaucoma involved or by a history of previous glaucoma surgery. Bleeding was a frequent complication, but was not related to resulting intraocular pressure. Other complications were rare. We conclude that combining cyclodialysis with cataract extraction is safe and effective, and is a suitable procedure when there is need for surgery to relieve severe glaucoma, along with a need for cataract extraction.
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PMID:Combined cyclodialysis and cataract extraction. 93 2

In the Miami Intraocular Lens Collaborative Study, 17 patients with glaucoma had a Copeland lens implanted at the time of cataract extraction. Seven additional glaucoma patients received a Binkhorst lens. Lens implantation did not adversely affect intraocular pressure or control of glaucoma, except in one patient who developed central retinal artery occlusion with rubeosis 1 1/2 years postoperatively and in one patient who had the lens removed because of iritis with uncontrolled glaucoma. Of 606 eyes that did not have glaucoma before cataract extraction and Copeland lens implant, many had transient postoperative pressure rise. Twenty-six (4.3%) developed prolonged pressure elevation. Nineteen patients were maintained on long-term medical therapy. The other seven were patients with iritis and glaucoma who had the implanted lens removed, including one who later had glaucoma surgery and one whose eye was later enucleated.
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PMID:Effect of the intraocular lens on intraocular pressure. 94 71

Nine cases are presented, six of them in detail, which suggest that there is a high risk of bullous keratopathy developing when the lens is removed for the treatment of acute glaucoma due to an intumescent cataract. In some cases the keratopathy is due to detachment of Descemet's membrane from the cornea. Acute glaucoma due to an intumescent cataract should be treated medically or by peripheral iridectomy. The lens should be removed only after the intraocular pressure has been normal and the cornea free of edema for at least 6 weeks.
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PMID:Bullous keratopathy following lens extraction in eyes with acute glaucoma due to intumescent cataract. 95 74

A new anaesthesia, through Chlormethiazol i.v. is described, which is especially used in cataract (lens) operations. There is no excitation during induction and the depth of anaesthesia (stage) depends on dosage-time ratio. Recovery is calm without undesirable side-effects. The intraocular pressure is significantly diminished during anaesthesia.
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PMID:[Distraneurin (Chlormethiazol) as an anaesthetic for high-risk cases in ophthalmology (author's transl)]. 96 64


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