Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.
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PMID:Current status of atopic dermatitis in Japan. 2205 99

Artificial iris implantation in a 38-year-old patient with post-traumatic aniridia is reported. The patient was assaulted in May 2013 and suffered a blunt trauma to his left eye. Directly after the assault, he was treated at the local hospital, where the upper eyelid wound and the lacerations of bulbar conjunctiva were sutured. One month later, he underwent a combined procedure of cataract extraction and anterior vitrectomy without the implantation of an intraocular lens. Next, he was hospitalised in our department, where apart from medical treatment of secondary, post-traumatic glaucoma, he was diagnosed with aphakia and almost complete aniridia. Afterhis intraocular pressure normalized, he had an artificial' iris prosthesis and intraocular lens implanted. The surgery was uneventful. The patient was very satisfied with the surgery. He reported a significant symptomatic improvement and resolution of photo-phobia and glare. The aesthetic result was very good. The customized artificial iris may be an effective treatment option in traumatic aniridia. It may improve the quality of life, as it reduces the unwanted optical phenomena occurring in aniridia. Furthermore, it offers excellent aesthetic result.
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PMID:Artificial iris implantation in a male with post-traumatic aniridia - case report. 2971 6