Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ghost cell glaucoma (GCG) has recently been described following vitrectomy, cataract extraction, and penetrating or blunt trauma. We describe the occurrence of GCG in a phakic eye with no prior ocular trauma or surgery following vitreous hemorrhage from diabetic retinopathy. We postulate the occurrence of a spontaneous rupture of the anterior hyaloid face which allowed passage of ghost cells into the anterior chamber. A therapeutic vitrectomy was complicated by intraoperative vitreous hemorrhage. Two weeks postvitrectomy, GCG recurred and was successfully controlled by irrigation through an anterior chamber approach. This is the procedure of choice in GCG following vitrectomy and may eliminate the need for a second vitrectomy.
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PMID:Nontraumatic ghost cell glaucoma--a case report. 395 94

Ghost cell glaucoma was described in 1975. The details of this glaucoma as it occurred following vitrectomy and following cataract extraction have been reported. This glaucoma occurred following trauma as well, and this report describes the clinical and pathologic characteristics. Fourteen patients, five with positive anterior chamber aspirate examinations, were studied. All had in common: (1) severe trauma to the eye, either blunt or penetrating, with hyphema and vitreous hemorrhage; (2) gradual clearing of the anterior chamber hemorrhage and conversion of fresh red blood cells to ghost cells in the vitreous cavity; (3) forward passage of ghost cells into the anterior chamber through a traumatic opening in the anterior hyaloid face; and (4) elevation of intraocular pressure caused by these cells approximately two weeks to three months following the trauma. The glaucoma required medical and often surgical therapy. The surgical procedure of choice was anterior chamber irrigation, which was often effective and is advised before proceeding to vitrectomy. The vitreous findings of an enucleated eye with ghost cell glaucoma are presented.
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PMID:Ghost cell glaucoma following trauma. 733 22