Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case is described in which the rubber cap of a vial containing Brucella abortus vaccine came off accidentally and some of the contents splashed in the eyes of a veterinarian. A uni-ocular keratoconjunctivitis developed. The other eye was similarly affected 1 week later. Brucella tests were negative. Two months later the Br. abortus titre was 1/640 and the Br. melitensis titre 1/320. Systemic treatment with tetracyclines, co-trimoxazole and streptomycin and local treatment with chloramphenicol and atropine had no effect. Two attacks of acute keratoconjunctivitis subsequently occurred within two hours of handling Brucella vaccine. In the right eye a corneal abscess developed, as well as uveitis and cataract. Extracapsular lens extraction was performed. Panophthalmitis followed and the eye was enucleated. The literature is reviewed and the possibility of a Brucella keratoconjunctivitis indistinguishable from viral keratoconjunctivitis is discussed.
 ...
PMID:[Brucella keratoconjunctivitis]. 678 62

Obstructive sleep apnea (OSA) is a disorder characterized by breathing cessation caused by obstruction of the upper airway during sleep. It is associated with multiorgan comorbidities such as obesity, hypertension, heart failure, arrhythmias, diabetes mellitus, and stroke. Patients with OSA have an increased prevalence of ophthalmic disorders such as cataract, glaucoma, central serous retinopathy (detachment of retina, macular hole), eyelid laxity, keratoconus, and nonarteritic anterior ischemic optic neuropathy; and some might require surgery. Given that OSA is associated with a high incidence of perioperative complications and more than 80% of surgical patients with OSA are unrecognized, all surgical patients should be screened for OSA (eg, STOP-Bang questionnaire) with comorbidities identified. Patients suspected or diagnosed with OSA scheduled for ophthalmic surgery should have their comorbid conditions optimized. This article includes a review of the literature and highlights best perioperative anesthesia practices in the management of ophthalmic surgical patients with OSA.
J Cataract Refract Surg 2019 07
PMID:Perioperative considerations and anesthesia management in patients with obstructive sleep apnea undergoing ophthalmic surgery. 3117 89