Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study is based on a detailed investigation of 12 cases of Irvine-Gass syndrome which was observed during the examination of 350 patients operated for pathological or senile cataract. The authors have found that: Males were affected more than females. Arteriol hypertension increases the frequency of the disease. The syndrome was found at an increase frequency in cases of nuclear cataract and in case where cataract was extracted by cryo-extraction. The bulge of the vitreous within the anterior chamber (without rupture of the anterior hyaloid membrane) causes a higher frequency of the disease. A similar observation was made when there was an incarceration of the vitreous to the surgical wound. The retreat of the edema was faster when the syndrome appeared earlier than the cataract operation. Whereas the restoration of good visual acuity did not depend upon the time of appearance of the disease. During the fluorescein study the following was observed. The possible participation of the chorio-capillaris layer in the pathogenicity of the disease. The diffusion of the fluorescein diminished with the improvement of the disease. Fluorescein angiography is unquestionably superior to simple ophthalmoscopy or the coloured photograph of the fundus of the eye, because the full extent of the existing damage can be revealed only through this method.
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PMID:[Irvine-Gass syndrome. Statistical and angiographic study]. 13 33

Cystic edema or the macula of Irvine-Gass syndrome, accompanied by a diminution of the central vision, is observed in 5% of the patients who have been recently operated for cataract. Only the fluorescin angiography can confirm the diagnosis with certainty. The inflammatory and vitreous theories explain most satisfactorily the pathogenesis of the condition.
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PMID:[Irvine-Gass-syndrome (author's transl)]. 91 99

In ten of 18 eyes from nine patients with Werner's syndrome, cataract surgery was complicated by wound dehiscence and its consequences: peripheral anterior synechiae (4), secondary epiretinal gliosis (4), cystoid macular edema (3) in the framework of Hruby-Irvine-Gass syndrome, unplanned filtering bleb (2), and post-operative anterior ischemic optic neuropathy (1). Additionally, corneal endothelial decompensation occurred in eight eyes. In view of the fibroblasts' reduced growth potential, we suggest small surgical incisions, extracapsular cataract surgery using phacoemulsification, intraocular irrigation solutions protecting corneal endothelium, nonabsorbable single knot sutures not removed before 1 year after surgery, and no local or systemic use of cortisone.
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PMID:Ophthalmological aspects in patients with Werner's syndrome. 264 84

Twenty-nine consecutive patients with vitreous incarceration in the wound after cataract surgery and cystoid macular edema (Irvine-Gass syndrome) were treated with Nd:YAG laser anterior vitreolysis. Fifty-five percent (55%) achieved two or more lines of stable visual improvement; 17% improved but with fluctuating levels of vision and persistent edema; 28% failed to improve, half of them because of coexisting ocular pathology. Visual improvement was achieved an average of 3.5 months after treatment. Persistent macular edema was associated with several types of anterior chamber intraocular lenses.
J Cataract Refract Surg 1989 May
PMID:Neodymium:YAG laser anterior vitreolysis for Irvine-Gass cystoid macular edema. 281 Jan 2

In ten of 18 eyes from nine patients with Werner's syndrome cataract surgery was complicated by wound dehiscence and its consequences: peripheral anterior synechiae (4X), secondary epiretinal gliosis (4X), cystoid macular edema (3X) in the framework of Hruby-Irvine-Gass syndrome, unplanned filtering bleb (2X), and postoperative anterior ischemic optic neuropathy (1X). Additionally, corneal endothelial decompensation occurred in eight eyes. In view of the fibroblasts' reduced growth potential, we suggest small surgical incisions, extracapsular cataract surgery using phacoemulsification, intraocular irrigation solutions protecting corneal endothelium, nonabsorbable single knot sutures not removed before 1 year after surgery, and no local or systemic use of cortisone.
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PMID:Ophthalmic surgical complications in Werner's syndrome: report on 18 eyes of nine patients. 343 6

Between 1973 and 1980 349 intraocular lenses were implanted after intracapsular and 470 after extracapsular cataract operation. The results and complications are evaluated: following intracapsular lens extraction a 4-loop Binkhorst lens (iris clip lens) was inserted in all cases. Following extracapsular cataract operation a 2-loop Binkhorst lens (iridocapsular lens) was implanted in 194, a 4-loop lens in 276 cases. The two complications occurring most frequently were an Irvine-Gass syndrome in 10% following intracapsular, and a disturbing secondary cataract necessitating a discision in 19% after extracapsular lens extraction. A dislocation-decentration of the pseudophakos was observed in some cases after extracapsular cataract operation. It is therefore recommended that the extracapsular be preferred to the intracapsular cataract extraction, that a 4-loop lens be implanted, secured by a transiridectomy suture, but that the haptic part of the intraocular lens should not be inserted in the capsular bag. It is of paramount importance, especially in young pseudophakic patients, to prescribe carefully an additional optical correction, preferably progressive glasses.
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PMID:[Extracapsular cataract extraction combined with the implantation of an intraocular lens (author's transl)]. 724 37

In a series of 1,000 consecutive intracapsular cataract extractions, the most important peroperative complications were rupture of the capsule in 6.5% of the cases and vitreous loss in 3.0%. The most important immediate postoperative complications were delay in wound closure in 2.7% of the cases, iritis in 2.9%, ocular hypertension in 3.4%, and some other complications. The late complications were an Irvine-Gass syndrome in 2.8% of the cases, an epithelial downgrowth in the anterior chamber in 0.6%, and a retinal detachment in 2%. alpha-Chymotrypsin often causes a temporary ocular hypertension (in at least 25.2% of the cases). The functional results are very good, when there is no pre-existing ocular pathology: in 90% of the cases the vision was 7/10 or more.
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PMID:Complications in 1,000 consecutive intracapsular cataract extractions. 745 24

Cataract removal with implantation of an intraocular lens (IOL) was performed in 66 cases of Fuchs' heterochromic cyclitis. After an average postoperative follow-up of 40 months (6 months to 10 years, 81.6% of cases obtained visual acuity superior or equal to 5/10 (16.6% with a final visual acuity of 10/10). Thirty cases were analysed, 27 had satisfactory binocular vision. Two complications explained this limited visual performance: vitreal disorders observed in 45.5% of cases were responsible for visual acuity inferior or equal to 5/10 in 23% of cases, glaucoma observed in 12.1% of cases (3 cases were secondary to cataract surgery), 25% of these patients with glaucoma lost all visual acuity and 62.5% had a high intraocular pression uncontrolled by surgery (5 cases). Other risk factors were less important: loss of transparency of intraocular lens caused by precipitates observed in one case, Irvine-Gass syndrome and retinal detachment observed in one case. The restoration of satisfactory binocular vision justifies the risks of intraocular lens implantation in cases of Fuchs' heterochromic cyclitis.
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PMID:[Functional results of cataract surgery with implantation in Fuchs' heterochromic cyclitis]. 833 Dec 53