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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Satisfactory visual results are reported in a series of 80 consecutive patients who underwent intracapsular cataract extraction with a four- or three-loop Binkhorst lens replacement. Nearly 50% of patients could see 20/30 or better unaided. However, results in the under 70 age group tend to be marred by macular edema, and in the over 80 age group by corneal edema, the latter occasionally being the result of lens instability because of an atonic pupil.
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PMID:Results after intracapsular extraction: the atonic pupil. 33 33

Macular edema has been observed frequently in man after cataract extraction, but pathogenic mechanisms remain unclear. Seven eyes of four young adult rhesus monkeys underwent lens extraction. The retinas and maculae of these eyes were examined by ophthalmoscopy fundus photography, fluorescein angiography, light and electron microscopy, and the horseradish peroxidase tracer technique. In the macular region, the blood-retinal barrier at the retinal vasculature was disrupted in three of the seven eyes. All three eyes had had vitreous loss during lens extraction. Horseradish peroxidase was observed both intracellularly and extracellularly in the maculae. In contrast, the blood-retinal barrier at both the retinal pigment epithelium and the retinal vasculature of the peripheral retina in most eyes was intact. We conclude that macular edema secondary to lens extraction is due to disruption of the blood-retinal barrier at the levels of the retinal vasculature and the retinal pigment epithelium.
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PMID:Experimental macular edema after lens extraction. 40 67

Fluorescein angiograms were performed in 90 patients the first and sixth week after removal of non-traumatic cataracts by phacoemulsification. The incidence of macular edema was found to be one half that reported in the literature for a comparable group of patients following intracapsular cataract extraction. The difference in incidence of macular edema between the phacoemulsification and the intracapsular groups seems dependent on the presence of the posterior capsule and perhaps the small size of the phacoincision. One of 21 maculas with angiographic evidence of edema developed clinical cystoid macular edema.
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PMID:Incidence of fluorescein angiographic subclinical macular edema following phacoemulsification of senile cataracts. 55 28

Cataracts are an enormous medical, financial, and social burden. At least 300,000 to 400,000 new, visually disabling cataracts occur yearly in the United States, and 5 to 10 million worldwide. Complications of modern surgical techniques alone probably result in at least 7,000 irreversibly blind eyes annulally in the United States, and a potential 100,000 to 200,000 worldwide. These figures must be refined through well-standardized prevalence surveys and careful monitoring of indications and results of surgery. Senile cataracts probably result from many, possibly compound, obscure causes. Race, altitude, dietary habits, and deranged carbohydrate metabolism are some that have been suggested. There is little basis for the common belief that senile cataracts are more prevalent, or mature more rapidly, in diabetics. Carefully conducted case control and long-term studies are needed to assess the importance of each of these factors and to identify additional ones. The rapid increase of intraocular lens implantation raises serious questions of safety and efficacy. Implantation increases the risk of corneal and macular edema, iritis, and reoperation for lens dislocation and membrane formation, while complicating the treatment of retinal detachments and retinovascular disease. They require controlled clinical evaluation.
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PMID:Cataracts as an epidemiologic problem. 84 37

Thirteen years after cataract extraction, a patient complained of diminished visual acuity. In the interim visual acuity was 6/6 (20/20), or 6/7.5 (20/25+2). Fluorescein angiography demonstrated cystoid macular edema. Except for vitreous adherence to the inner surface of the cataract wound, no ocular cause for the macular edema was apparent.
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PMID:Cystoid macular edema occurring 13 years after cataract extraction. 86 51

Follow-up examinations, ranging from four to more than 20 years, were performed on 100 patients with chronic cyclitis whose ages at onset were from 4 to 58 years. Cataracts were found in 42% of eyes and macular disease secondary to macular edema in 28% of eyes. Band keratopathy, glaucoma, retinal detachment, retinoschisis, vitreous hemorrhage, retinal hemorrhage, and vessels leaving the disk margin were also noted. The complications resulting in decreased vision in chronic cyclitis were macular edema in active cases and macular degenerative changes in the late inactive stages. Of all eyes with final visual acuity of 6/12 (20/40) or less, 74% had permanent, late macular changes secondary to earlier cystoid macular edema. Vitreous opacities or cells, or both, caused decreased visual acuity in the early active stages of chronic cyclitis but were not major factors in the ultimate visual prognosis in the late inactive stages. At the final examination, vitreous opacities caused a visual loss in only 9% of the eyes that had visual acuity of 6/12 (20/40) or less. It was difficult to determine whether corticosteroids caused cataract formation and glaucoma.
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PMID:Complications of chronic cyclitis. 94 80

In a prospective study, the incidence of cystoid macular edema for two groups of patients was found at six weeks following surgery. The first group who underwent cataract extraction had a 50 per cent incidence. The second group who underwent elective glaucoma surgery had no patient with cystoid macular endema. At six weeks, 16 per cent of those patients who had originally developed cystoid edema, had a visual acuity of 6/12 or less, with no other cause for the poor visual result. The two major differences between these two groups of patients were the actual cataract extraction, and the presence of postoperative vitreous inflammation. No factors were noted to cause persistence of the aphakic macular edema although the technique of cataract extraction and vascular disease were implicated.
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PMID:Aphakic macular edema: incidence and pathogenesis. 111 Jan 41

Six months after cataract extraction, a 71-year-old man had cystoid macular edema confirmed by fluorescein angiography. Microscopic examination revealed cystoid spaces in the outer plexiform and outer nuclear layer of the neurosensory retina. Chronic inflammatory cells were scattered throughout the ciliary body. Inflammatory cells were also present in a section of iris that had an adherent strand of vitreous leading to the pars plana. Comparison of these findings with other related clinical entities supported the hypothesis that ciliary body inflammation may play a significant role in postcataract extraction macular edema.
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PMID:Pathogenesis of aphakic macular edema. 115 56

A 69-year-old man with bilateral open-angle glaucoma and nonfiltering iridencleisis scars underwent combined cataract extraction and glaucoma filtering operations in each eye. Later, he again required intensive medical therapy including topically applied echothiophate iodide, epinephrine, and acetazolamide to control his glaucoma. Topical instillation of epinephrine repeatedly resulted in reversible cystoid macular edema in each eye. The macular changes were documented by fluorescein angiography. The clinical and angiographic features of the macular edema in this patient did not differ from cystoid macular edema seen in other ocular conditions.
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PMID:Cystoid macular edema associated with topically applied epinephrine in aphakic eyes. 116 85

A follow-up of 120 pseudophakic eyes of 85 patients that underwent surgery for senile cataract showed a definite superiority of extracapsular surgery over intracapsular surgery as far as the longterm fate of the retina concerns. Comparable series have been chosen. Retinal detachment did not occur in extracapsular eyes that never had posterior capsulotomy, and occurred most often after intracapsular surgery. Signs of previous or existing maculopathy were searched for with the usual tests (funduscopy, visual acuity, Amsler test) and moreover with Haidinger's brushes test. The macula turned out to have least suffered after extracapsular surgery without capsulotomy and most after intracapsular surgery. Haidinger's brushes test is a valuable tool for the detection of postoperative macular edema.
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PMID:Retinal accidents in pseudophakia--intracapsular vs extracapsular surgery. 127 31


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