Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We describe the binocular status of four patients, aged 5, 6, 10, and 13 years, who had a unilateral congenital cataract removed in the first few months of life. A contact lens had been fitted in all cases and was worn continuously. The normal eye was occluded for approximately 90% of the waking day until at least the age of 4 years. Two patients developed an esotropia and two an exotropia. Best-corrected visual acuity is 20/40 or better in both the aphakic and the normal eye. The patients' binocular status was assessed with a full eye examination, tests for fusion in free space with prism neutralization, tests for stereopsis, and examination on the Clement Clarke synoptophore. All patients showed simultaneous perception but no real fusion, resulting in diplopia. A vertical bobbing effect was noted at the angle of neutralization similar to that reported by us in cases of central fusion disruption.
J Pediatr Ophthalmol Strabismus
PMID:Unilateral congenital cataract: binocular status after treatment. 270 79

Early detection of visual deficits is of most importance in childhood. To be adequately treated; it requires systematic screening before 18 months of age. Basic tests include objective refraction study (skiascopy), preferential sight test with estimation of visual acuity which is possible after 3 months of age, and, if poor vision, is found, electroretinography evoked visual potentials is performed. Many disorders can be recognized early on and treated (mainly strabismus, congenital cataract or glaucoma). The early correction of refractive disorders results in good visual development and subsequent facility in reading and writing.
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PMID:[Detection of vision disorders in newborn infants and children]. 271 35

Clinical findings, course, treatment, and complications of intermediate uveitis in children is analyzed in a series of 60 patients. While generally a chronic indolent disease, in the pediatric age group acute anterior uveitis is the presenting symptom rather than the milder symptomatology characterized in the adult with a similar syndrome. The etiologic evaluation of these patients was unrewarding. The great majority of patients improved following the use of periocular corticosteroid injections and retinal cryopexy, and immunosuppressive agents were infrequently employed in the management of the disorder. Cataract formation, secondary glaucoma, band keratopathy, vitreous hemorrhage, and papillitis were seen as complications. A treatment algorithm is presented.
J Pediatr Ophthalmol Strabismus
PMID:Pediatric intermediate uveitis. 272 76

Classical galactosemia due to a deficiency of galactose-1-phosphate-uridyl transferase, is an autosomal recessive disorder of galactose metabolism with an incidence in Ireland of one in 30,000 births. It can result in cataract formation through the accumulation of galactitol within the lens. Seventeen children with transferase deficient galactosemia were studied. Early diagnosis followed by a galactose-free diet and tight biochemical control prevented cataract formation in 13 cases after a mean follow-up of 6.3 years. Cataracts did not regress in all patients commenced on diet by 6 weeks but early treatment prevented progression. The ophthalmologist may play an important role in the monitoring of patients with this disease as the recognition of new lens opacities by slit-lamp biomicroscopy may be the most sensitive initial index of inadequate biochemical control.
J Pediatr Ophthalmol Strabismus
PMID:Ophthalmic findings in classical galactosemia--a screened population. 276 Jul 88

Developmental glaucoma, which cannot be controlled by conventional techniques, poses a difficult problem. Twenty-three eyes of 18 patients with developmental glaucoma underwent a two-stage implantation of the double template Molteno valve with follow-up between 12 and 84 months. The final pressure with medication was less than 21 mm Hg in 78% of the cases. These results were obtained in four out of four eyes with primary congenital glaucoma, six out of eight eyes with secondary congenital glaucoma, and eight of 11 eyes in which glaucoma followed surgery for congenital cataract. We feel that two-stage implantation of Molteno valves has a place in the management of difficult developmental glaucomas and is a reasonable early option when glaucoma occurs following surgery for congenital cataract.
J Pediatr Ophthalmol Strabismus
PMID:The use of two-stage Molteno implants in developmental glaucoma. 291 9

A combined needle holder and scissors was designed in two sizes, one for use in muscle surgery and oculoplastic surgery and the other in microsurgery. They have been used with suture sizes 10-0 to 6-0 and needles from 75 to 200 micron in diameter and have been found to be useful in cataract, squint, and oculoplastic surgery.
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PMID:A combined needle holder and scissors. 305 87

We report an 11-month-old infant with cri du chat syndrome and cataracts. The chromosomal abnormality was transmitted via a balanced 5/11 translocation from a phenotypically normal mother. The child underwent bilateral cataract extraction and was fitted with extended wear contact lenses. Congenital cataracts may be associated with cri du chat syndrome.
J Pediatr Ophthalmol Strabismus
PMID:Lensectomy in an infant with cri du chat syndrome and cataracts. 316 27

The presence of cystoid macular edema (CME) after cataract extraction in the pediatric age group could adversely affect rapid visual rehabilitation of the eye by contributing to irreversible amblyopia. Several previous studies, including one by our group, have addressed this problem. Hoyt's observations of CME in ten of 27 eyes undergoing lensectomy-vitrectomy procedures have stirred renewed interest in this topic. The current study includes 12 eyes undergoing lensectomy-vitrectomy procedures, five eyes undergoing manual extracapsular procedures (ECCE) with discission of the posterior capsule, three eyes undergoing ECCE without discission of the posterior capsule, and three eyes undergoing secondary discissions. No CME was found angiographically on postoperative evaluation.
J Pediatr Ophthalmol Strabismus
PMID:Cystoid macular edema in pediatric aphakia. 317 31

Within the last 18 months the authors have measured, in cases of juvenile cataract seen by them, the axial length of the eye and other parameters. As a control group, children from the authors' squint clinic, with various refractive errors, were examined. With the data thus gathered, correlation and regression analyses were performed, postoperative refraction values were calculated, and eye growth in phakic eyes was compared with that in aphakic eyes. Regression formulas were established which enabled the authors to calculate eye length at a given age, to determine the postoperative refraction of their juvenile cataract patients with great accuracy, and, so far, to prove that there is no significant difference between phakic and aphakic eyes as regards growth.
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PMID:[Ultrasound biometry in childhood]. 332 35

Cryoprecipitate and thrombin were used to prevent bleeding and induce permanent conjunctival attachment in ten cases of retinal detachment, 40 cases of extracapsular cataract extraction, and ten cases of strabismus. This method proved to be a good alternative to suturing the conjunctiva in each of the above-mentioned surgical procedures, and appears to result in a better and more comfortable postoperative course.
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PMID:Use of fibrin glue in ocular surgery. 334 59


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