Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper reviews the available evidence concerning the side effects of atypical antipsychotics, including weight gain, type II diabetes mellitus, hyperlipidemia, QTc interval prolongation, myocarditis, sexual side effects, extrapyramidal side effects and cataract. Some recommendations about how to prevent and manage these side effects are also provided. It is concluded that atypical antipsychotics do not represent a homogeneous class, and that differences in side effects should be taken into account by clinicians when choosing an antipsychotic for an individual patient.
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PMID:Side effects of atypical antipsychotics: a brief overview. 1845 71

This research evaluated the anatomic pathology of rats fed diets containing ground beef which had been treated with aqueous chlorine. The anatomic pathology of 240 rats fed 92 d with diets containing ground beef treated with 0, 50, 200 or 600 ppm chlorine was carried out according to National Institutes of Health bioassay pathology procedures. The major rat tissues were evaluated and the incidence of histopathological conditions was recorded. The inclusion of chlorine-treated meat in the diet was not associated with any increase in incidence of neoplastic lesions, inflammatory lesions or degenerative changes. However, all male rats fed the meat diet both with or without chlorine exhibited mild to moderate hepatic fatty metamorphosis. In all likelihood, the fatty livers were due to the high fat content of the diet (about 35%). The adrenal glands of the control and treated males exhibited fatty metamorphosis. This effect is not explained by diet because even the male rats on the commercial rat feed had fatty adrenal glands. Other histopathologic conditions such as focal hepatitis, triaditis, focal myocarditis, focal lymphocytic infiltration, chronic murine pneumonia, chronic tracheitis, focal acute gastritis, dacryoadenitis, cataract, hyperplastic hepatic nodule or ultimobranchial cysts, when found were not associated with any treatment or sex group. The treatment of ground beef with aqueous chlorine before incorporation into a diet fed rats for 92 d exhibited no apparent effect on the anatomic pathology of rats.
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PMID:Subacute Study of Rats Fed Ground Beef Treated with Aqueous Chlorine - Anatomic Pathology. 3096 86