Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085693 (acute appendicitis)
 3,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fifty patients with a presumptive diagnosis of acute appendicitis based on usual Western medicine criteria (e.g., McBurney point tenderness, increase WBC, history of nausea, etc.) were examined prospectively for tenderness of the Lanwei acupoint, just prior to the administration of general anesthesia, to evaluate this well known 'Appendix' point as a useful aid to diagnosing appendicitis. The presence or absence of tenderness was statistically not a good indicator of appendicitis.
Pain 1988 Apr
PMID:The lack of importance of Lanwei point in the diagnosis of acute appendicitis. 338 May 55

This retrospective study was conducted into 1.506 patients who had been admitted to the author's hospital for suspicion of acute appendicitis, between 1971 and 1979. Indications for appendectomy were handled with generosity, and primary laparotomy was applied to 44.2 per cent of all cases. Perforated appendicitis was of low incidence, accounting for only three per cent, while no acute inflammatory lesions were recordable at all from 36 per cent of removed appendices. Follow-up checks were made on all patients who had not been operated on, in the first place, not later than five years from first diagnosis. Only 15 per cent of these patients had to be eventually appendectomised. For them distribution of histological diagnoses was similar to that of patients with surgery as primary approach. Recurrence of pain was reported by one third of patients without surgery. However, only 14.9 per cent of them saw a doctor on their problem, and only 3.7 per cent had to be rehospitalised. Primary wait-and-see attitude caused no further increase in the incidence of perforated appendicitis.
 ...
PMID:[Indications for appendectomy. A retrospective analysis]. 344 43

An evaluation was made of the histological material obtained from all 1529 appendices removed during the last 5 years at Southmead Hospital, Bristol, in order to elucidate possible relationships between the incidence of Enterobius vermicularis and the origin of inflammation in the appendix. In total, 1419 appendices were removed as cases of clinical appendicitis and 110 in the course of another surgical procedure. E. vermicularis was identified in 2.7 per cent of patients with clinical appendicitis and was most commonly seen in appendices with either chronic inflammation or where the appendix was histologically normal. E. vermicularis was rarely associated with histological changes of acute appendicitis. No cases of E. vermicularis infestation occurred in appendices removed during the course of other surgical procedures. The results suggest that, although E. vermicularis may have a causal role in appendicular pain and chronic inflammation, it is rarely related to acute appendicitis.
 ...
PMID:Role of Enterobius vermicularis in the aetiology of appendicitis. 365 83

776 patients seen in our emergency ward with abdominal pain for less than one week duration were prospectively analysed. In 49% of these patients no cause was found and 19% had acute appendicitis. Among 180 appendectomized patients, 147 (82%) had acute appendicitis whereas 33 (18%) had no inflammation of the appendix. Clinical presentation with a pain duration of less than 36 hours, steady abdominal pain, guarding in the right iliac fossa and a white cell count above 12,000/mm3 (12 g/l) were the best criteria for prediction of acute appendicitis versus a normal appendix. Perforated appendicitis was found in 18% of the patients with acute appendicitis but in only one patient for whom appendectomy had been deferred on the grounds of atypical presentation. Thus, in most cases, the perforation was preexistent to admission. We therefore recommended a 24-48-hour observation period for patients with uncertain diagnosis. Rates of normal appendices and perforated appendices of about 20% seem to be difficult to improve upon.
 ...
PMID:[A prospective study of 776 cases of acute non-traumatic abdominal pain. Acute appendicitis and its diagnosis]. 367 66

The emergency physician is frequently frustrated by the symptom of recurrent abdominal pain. This complaint is particularly troubling when the patient localizes the pain to the right lower quadrant. On an isolated visit, acute appendicitis is the condition which demands primary consideration, because of both its frequency and the consequences of failure to make a prompt diagnosis. When right lower quadrant abdominal pain is recognized as being recurrent, the emergency department physician must consider a broader range of diagnostic possibilities. This illustrative case presents one unusual element of the differential diagnosis of this symptom.
 ...
PMID:Eosinophilic granuloma of the appendix. 384 39

We conducted a retrospective study of 305 patients hospitalized with abdominal pain suggestive of acute appendicitis. Signs, symptoms, and laboratory findings were analyzed for specificity, sensitivity, predictive value, and joint probability. The total joint probability, the sum of a true-positive and a true-negative result, was chosen as a diagnostic weight indicative of the accuracy of the test. Eight predictive factors were found to be useful in making the diagnosis of acute appendicitis. Their importance, according to their diagnostic weight, was determined as follows: localized tenderness in the right lower quadrant, leukocytosis, migration of pain, shift to the left, temperature elevation, nausea-vomiting, anorexia-acetone, and direct rebound pain. Based on this weight, we devised a practical diagnostic score that may help in interpreting the confusing picture of acute appendicitis.
 ...
PMID:A practical score for the early diagnosis of acute appendicitis. 184 49

In order to determine whether any clinical or laboratory findings were helpful in differentiating acute appendicitis (AP) from acute pelvic inflammatory disease (PID), this retrospective study was undertaken. Records of all female patients 12 to 50 years of age, undergoing laparotomy with a preoperative diagnosis of AP over the past 15 years, were reviewed and pertinent data recorded. In comparing AP (n = 106) with PID (n = 39), longer duration of symptoms, relationship of onset of pain to the menstrual cycle, and frequent requests for gynecological consultation distinguished the PID from the AP cases. Although complete reliance cannot be placed on any clinical or laboratory finding in differentiating AP from PID, the final satisfactory outcome justifies laparotomy when the diagnosis cannot be established by other means.
 ...
PMID:Appendicitis versus pelvic inflammatory disease. A diagnostic dilemma. 398 88

The data on 80 cases of ovarian dysgerminoma are presented. The average age of patients was 19.1. In 9 out of 18 menstruation--free patients dysgerminoma was associated with genital infantilism and intersexuality. Pain was the most frequent symptom (70%). In 82%, correct diagnosis was established during primary examination. Among the most frequent misdiagnoses were acute appendicitis or pregnancy. Stage I tumor was established in nearly 70%. Unilateral involvement was registered in 83.5% of cases. Metastatic spread was limited to peritoneal cavity in 19.2%, paraaortic lymph nodes were involved in 16.4%. Five-year survival rate was 71.4%. Such characteristics of tumor process as stage and size of neoplasm proved to be of the highest prognostic value. The choice of a treatment modality was found to produce an insignificant effect on the results of therapy.
 ...
PMID:[Clinical picture and treatment of ovarian dysgerminoma patients]. 399 62

Abdominal pain and fever after an uncomplicated elective abortion usually point to incomplete abortion and endometritis. We treated a woman for acute suppurative appendicitis one week after such an abortion. When fever, nausea, vomiting and pain are not relieved by the standard doses of medication, acute appendicitis must be added to the usual gynecologic differential diagnoses.
 ...
PMID:Ruptured appendix after elective abortion. A case report. 622 52

After immunohistochemical staining appendices without active inflammation but producing symptoms of appendicitis (N = 24) were compared with a control group of appendices removed incidental to another procedure (N = 26). Staining for neurone specific enolase (NSE) showed more instances of nerve 'hyperplasia' in the control group than in the appendices generating pain refuting the concept of neuroappendicopathy based on quantitative nerve changes. Serotonin staining identified subepithelial neuroendocrine cells (SNC) in 85 per cent of the specimens. All cases showed serotonin immunoreactive enterochromaffin cells (EC). Staining for serotonin was significantly decreased in the SNC in the painful group. There were no significant differences between the two groups in staining intensity of SNC and EC for substance P (SP). Vasoactive intestinal polypeptide (VIP) was not seen in the SNC and EC and there were no differences in nerve fibre staining for VIP. Serotonin is a neurotransmitter as well as mediator of inflammation. It is suggested that reduced staining for serotonin in painful appendices reflects discharge of stores which could be instrumental in inducing the pain in these cases. Continued serotonin release may then lead to acute appendicitis.
 ...
PMID:Serotonin and its possible role in the painful non-inflamed appendix. 637


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>