Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085693 (acute appendicitis)
 3,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A histologic examination was made of all appendices delivered to the Dept. of Pathology, Sundby Hospital, Copenhagen, in 1980-87, to ascertain the incidence of Enterobius vermicularis (pinworm) and the possible relation to acute appendicitis. Altogether 2267 appendices were examined, and E. vermicularis was identified in 4.1%. The highest incidence occurred in the 6- to 15-year age group. Infestation was more frequent in female than in male appendices, with the ratio of 1 male to 1.8 females, except in the 11- to 15-year age group, in which the ratio was 1. There was a highly significant difference in the incidence of E. vermicularis in normal appendices and in inflamed appendices, which may indicate that 1) the presence of E. vermicularis in the appendix can give the symptoms of acute appendicitis, or 2) E. vermicularis leaves or does not enter an inflamed appendix.
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PMID:Appendicitis and Enterobius vermicularis. 185 57

The role of Enterobius vermicularis in appendicitis has been disputed. The aims of this retrospective study were to determine the prevalence of E. vermicularis in surgically removed appendices and to relate this to the age and sex of the patient, the time of the year, the presence of symptoms and the histological findings. The study included all appendices received in this laboratory during the 5 year period from 1984 through to 1988. There were 1867 appendices during this period of which 1108 were acutely inflamed and 759 were not inflamed (although 149 of these showed other pathological changes). The mean age distribution of all patients was 22.8 years. Enterobius vermicularis was identified in 63 appendices (3.4%). Infestation was more frequent in female (4.6%) than in male (1.9%) patients. The peak age was 12.8 years in females and 12.1 years in males. Of 63 patients who had E. vermicularis, 98% presented with symptoms of acute or recurrent appendicitis, yet 40 had no histological evidence of appendicitis or mucosal invasion by the parasite and only four had other possible explanations for abdominal pain. In an analysis of the subgroup of 147 patients who had incidental appendectomy at the time of laparotomy for other reasons, only one had E. vermicularis. It is concluded that E. vermicularis occurs more frequently in uninflamed appendices. It may be a cause of symptoms resembling acute appendicitis although the mechanism for this does not involve mucosal invasion by the parasite.
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PMID:Enterobius vermicularis: a possible cause of symptoms resembling appendicitis. 794 67