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Query: UMLS:C0085693 (acute appendicitis)
 3,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Necrotizing fasciitis, although rare, is one of the more serious, life-threatening complications of missed acute appendicitis. Patients who are predisposed to developing necrotizing fasciitis, regardless of the cause, are typically immunocompromised. We present a case of a 49-year-old immunocompetent female whose diagnosis of acute appendicitis was missed and who subsequently developed necrotizing fasciitis of the abdominal wall and flank. She recovered 1 month after admission due to aggressive surgical and medical therapy.
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PMID:Necrotizing fasciitis due to appendicitis. 1053 May 43

Necrotizing fasciitis (FN) is a deep infection of the subcutaneous tissue and fascia, resulting in its progressive destruction. Usually it evolves very quickly. The authors present a case to FN abdominal wall, an extremely rare complication of acute appendicitis. A child had surgical removal of the appendix because of gangrenous acute appendicitis, which evolved into severe infection, with pain and inflammatory process of the abdominal wall. After diagnosis, he underwent a surgical debridement of the abdominal wall and drainage of intraperitoneal abscess. Antibiotic therapy, surgical debridement and successive dressings were done and at 22nd day a dermo-epidermal graft was done in a small residual lesion of the abdominal wall. Because the prognosis is closely related to time to correct diagnosis and initiation of appropriate therapy, it's extremely important that this diagnosis is considered.
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PMID:[Necrotizing fasciitis post-acute appendicitis]. 2285 99

Acute appendicitis is one of the most common causes of acute abdominal pain. Accurate diagnosis is often hindered due to various presentations that differ from the typical signs of appendicitis, especially the position of the appendix. A delay in diagnosis or treatment may result in increased risks of complications, such as perforation, which is associated with increased morbidity and mortality rates. Necrotizing fasciitis caused by perforated appendicitis is extremely rare. We herein report a case of 50-year-old man presenting with an appendiceal abscess in local hospital. After ten days of conservative treatment with intravenous antibiotics, the patient complained about pain and swelling of the right lower limb and computed tomography (CT) demonstrated a perforated appendix and gas and fluid collection extending from his retroperitoneal cavity to the subcutaneous layer of his right loin and right lower limb. He was transferred to our hospital and was diagnosed with necrotizing fasciitis caused by perforated appendicitis. Emergency surgery including surgical debridement and appendectomy was performed. However, the patient died of severe sepsis and multiple organ failure two days after the operation. This case represents an unusual complication of a common disease and we should bear in mind that retroperitoneal inflammation and/or abscesses may cause necrotizing fasciitis through lumbar triangles.
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PMID:Necrotizing fasciitis caused by perforated appendicitis: a case report. 2604 63