Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085693 (acute appendicitis)
 3,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A clinical study of 22 cases of ovarian hemorrhage suggests that intraabdominal hemorrhage of 100 ml and above should be surgically treated. The study also found polycystic tendency and increased peripheral blood white blood cell count. 13 cases which were pathologically treated were diagnosed to be corpus luteum hemorrhage. Out of 26 cases with ovarian hemorrhage seen at Almeida Hospital in Oita, Japan, between 1976 and 1987, 4 cases were eliminated from the study because of pregnancy. No significant difference was found in terms of number of pregnancies or number of child births. 19 of 22 cases belonged to the age group 20-34. Hemorrhage occurred in 9 cases during the premenstrual period, from the 22nd day to the 28th day. It occurred after induced abortion in 5 cases. All 22 women complained of lower abdominal pain. 15 were diagnosed to have puncture of Douglas pouch. In 16 out 22 cases hemorrhage occurred in the left ovary. This is due to the fact what many with right side abdominal pain had already been operated elsewhere because of suspected appendicitis. No fever over 38 degrees celsius was found, but 8 cases had a slight temperature. 5 of 22 cases showed a peripheral blood white blood cell count over 10,000. This combination of two factors proved to be not so reliable in distinguishing between acute appendicitis and ovarian hemorrhage. 9 out of 11 cases which were diagnosed to have intraabdominal hemorrhage of 100 ml and above were still hemorrhaging at the time of operation. Therefore, hemorrhage of 100 ml, not 200 ml and above as in the past, should be surgically treated.
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PMID:[Idiopathic ovarian hemorrhage]. 336 Nov 83

BACKGROUND Paracoccidioidomycosis is an endemic mycosis in Central and South America caused by the thermally dimorphic fungus Paracoccidioides brasiliensis. Despite its self-limited course and usually asymptomatic infection, some patients may present with a systemic illness mimicking multiple conditions and thus question the general state of their immune system. CASE REPORT A 28-year-old male presented to the hospital with fever, dry cough, and non-pruritic rash with no characteristic distribution for the past 10 days. Past medical history revealed that the patient had worked as a farmer three years ago, had abused cocaine paste over the same period, and also had in the last month presented to the hospital for acute appendicitis. Initial laboratory tests revealed hypereosinophilia greater than 10,000 eosinophils/mL. Infection of P. brasiliensis was confirmed by lymph node, skin, and colonoscopy biopsies. After treatment with itraconazole, the patient's eosinophil count returned to normal and his symptoms resolved. CONCLUSIONS Paracoccidioidomycosis may present as a systemic illness with only marked eosinophilia on initial diagnostic tests. Furthermore, in our patient's case, the high degree of eosinophilia may have contributed towards the patient's appendicitis in the weeks preceding the subacute infection. It is possible that the patient's history of working at a farm and abusing cocaine paste may have contributed to the initial colonization by the fungus.
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PMID:Hypereosinophilia Secondary to Disseminated Paracoccidioidomycosis. 2904 30