Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Target Concepts:
Gene/Protein
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Query: UMLS:C0085693 (
acute appendicitis
)
3,606
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We report a case of neuronal hypertrophy associated with
acute appendicitis
in which significant neuronal fibers and the number of ganglion cells increased in the absence of inflammatory cells. Differential diagnosis from diffuse ganglioneuromatosis by the pathologic findings of resected specimen was difficult. A 33-year-old Japanese female visited our hospital complaining of acute abdominal pain. The patient underwent appendectomy upon the diagnosis of
acute appendicitis
on the day of admission. Postoperative examinations found no neoplastic lesions in other organs or inherited disorders such as
multiple endocrine neoplasia
(
MEN
) type 2b and von Recklinghausen's disease (VRD). The pathologic diagnosis was neuronal hypertrophy of the appendix. Because the clinical outcomes of diffuse ganglioneuromatosis and neuronal hypertrophy of the gastrointestinal tract are quite different, clinical and pathologic examination should be carefully carried out for lesions in which significant proliferation of neuronal components is seen.
...
PMID:A case of diffuse neuronal hypertrophy in acute appendicitis. 2311 55
