Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085632 (apathy)
 4,089 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CLUAP1 10.9
BEC1 9.9
Kv12.2 9.3
DC15 9.1
RAPGEF3 9.0
MRGPRD 8.9
YWHAQ 8.7
NPI 8.6
SHAP 8.5
LBX1 8.4
EXOC2 8.4
TSEN54 8.2
SCN9A 8.2
hSyn 8.1
IkappaB kinase complex-associated protein 8.0
cAMP-GEFII 7.8
CYP46 7.7
PRND 7.5
PRP-3 7.5
D3nf 7.4
DAOA 7.4
EIF2B5 7.3
FTD 7.3
EHMT1 7.3
STN 7.3
Nav1.3 7.3
DBS 7.2
GDS 7.2
MAPK6 7.1
mutS homolog 2 7.0
CBX8 6.9
LARS 6.9
Pgp1 6.9
Nav1.7 6.9
SLC5A1 6.9
Hos 6.9
DCTN1 6.9
MDB 6.8
CLTC 6.8
dynactin subunit 6.8
SCA17 6.7
SIX5 6.6
MCP-3 6.6
epsilon-sarcoglycan 6.6
ADAS 6.6
OFC 6.5
SKT 6.5
COXI 6.4
CHMP2B 6.4
GRN 6.4
SANS 6.4
C9orf72 6.4
PDHA1 6.4
CADASIL 6.4
chromosome 9 open reading frame 72 6.3
IL-1R2 6.3
VAPB 6.3
RagA 6.3
TE2 6.2
Dynactin 6.1
p92 6.1
HLA-Cw 6.1
CHRFAM7A 6.0
TAC1 6.0
SAPS 6.0
INCA 6.0
Complement C3 6.0
Jon 5.9
ARTEMIS 5.9
YWHAE 5.9
HDS 5.9
MOR-1 5.9
TRKA 5.8
mGlu3 5.8
Cholinesterase 5.8
alpha synuclein 5.8
PGRP 5.8
CUL3 5.8
CBX3 5.7
TDP-43 5.7
more...
Disease
Disorders of psychological development 12.9
pathological emotionality 12.9
Apathetic thyrotoxicosis 11.9
Anosodiaphoria 11.9
BDSD 11.9
witzelsucht 11.3
abulia 11.0
Frontal lobe degeneration 10.9
HMN7B 10.9
moria 10.3
Akinetic mutism 10.2
Fuchs' syndrome 9.9
Deluded 9.9
Poverty of speech 9.9
Periodic catatonia 9.8
Infantile botulism 9.8
BPSD 9.7
blunted affect 9.7
panmyelophthisis 9.6
Fungal meningitis 9.6
Dementia in Parkinson's disease 9.5
Uremic encephalopathy 9.5
Cortical laminar necrosis 9.3
SYNDROMES 9.2
mild memory disturbance 9.2
psychosomatic reaction 9.1
Pullorum disease 9.1
nihilistic delusion 9.0
temper tantrum 9.0
frontal lobe syndrome 9.0
Kleine-Levin syndrome 8.9
Fetal asphyxia 8.8
hypersexuality 8.7
Sleep attacks 8.7
quarrelsomeness 8.7
anosognosia 8.6
Stereotypic behavior 8.5
transcortical aphasia 8.5
onychogryphosis 8.5
simple schizophrenia 8.4
Abnormal behavior 8.4
Frontal lobe 8.4
Performance anxiety 8.4
Chronic depression 8.4
disinhibition 8.4
chronic organic brain syndrome 8.3
Congenital myotonic dystrophy 8.3
flat affect 8.3
impulse control disorder 8.3
Behavioral problems 8.3
sexual difficulty 8.3
sex addiction 8.3
Frontotemporal dementia 8.2
alcoholic encephalopathy 8.2
anhedonia 8.2
arteriosclerotic dementia 8.1
Lack of interest 8.1
Superior sagittal sinus thrombosis 8.0
sea sickness 8.0
Ehrlichia canis infection 8.0
EPV 7.9
Frohlich 7.9
hyperlysinemia 7.9
polioencephalitis 7.8
hallucinosis 7.8
depressive psychosis 7.8
delusions 7.8
derealization 7.7
amnesic syndrome 7.7
mutism 7.7
hallucinations 7.6
psychogenic amnesia 7.6
racing thoughts 7.6
Hashitoxicosis 7.6
pressured speech 7.5
Progressive Aphasia 7.5
Kluver-Bucy syndrome 7.5
GISA 7.5
solvent abuse 7.5
coenurosis 7.3
more...
Symptom
apathy 12.9
dribbling saliva 12.9
amimia 11.0
clammy skin 9.1
Behavioral symptoms 8.9
personality change 8.6
Psychiatric symptoms 8.2
Positive and Negative Symptoms 7.9
hyperosmia 7.8
not coping 7.7
hypersomnia 7.7
motor symptom 7.6
Psychotic Symptoms 7.6
visual hallucination 7.6
carpopedal spasm 7.4
Hemiballism 7.3
bewilderment 7.1
agitation 7.0
prostration 7.0
staggering gait 6.8
bradykinesia 6.5
frequent urination 6.5
male puberty 6.5
auditory hallucination 6.5
adipsia 6.4
lassitude 6.4
Extrapyramidal symptoms 6.3
emaciation 6.2
elevated mood 6.2
localized edema 6.2
catatonia 6.1
drooling 6.1
meningism 6.1
forgetfulness 6.1
hopelessness 6.1
loss of taste 6.0
chorea 5.9
alexithymia 5.9
hyperesthesia 5.9
Decreased activity 5.9
memory loss 5.9
Signs and Symptoms 5.8
anorexia 5.8
lethargy 5.6
physical exhaustion 5.6
Deafferentation 5.5
sleepiness 5.5
hypalgesia 5.5
ataxic gait 5.4
impaired motor coordination 5.3
aphagia 5.3
Depressive symptoms 5.3
giddiness 5.3
giddiness 5.3
Opposition 5.2
hypertonia 5.2
blackout 5.1
decreased appetite 5.1
dysarthria 5.0
anal pain 5.0
polydipsia 5.0
aphonia 5.0
pallor 4.9
incoordination 4.9
asthenia 4.9
tremor 4.8
nasal discharge 4.8
consciousness disturbance 4.8
hyperemesis gravidarum 4.8
excessive sweating 4.8
ataxia 4.7
hypotonia 4.7
insomnia 4.6
No adverse effect 4.6
torticollis 4.6
fatigue 4.5
paresis 4.5
intention tremor 4.5
muscle rigidity 4.4
Poor sleep 4.4
more...
Drug
Bifemelane hydrochloride 9.9
Solganal 9.8
Clopenthixol 9.3
Percocet 8.9
Darvon 8.7
Foscavir 8.5
Equipoise 8.5
Istradefylline 8.2
Reminyl 8.0
Frontal 7.9
Exelon 7.8
FML 7.6
Exelon 7.6
Anidulafungin 7.5
DDF 7.3
DBS 7.2
PAPM/BP 7.0
Folic Acid 6.9
Dextropropoxyphene 6.9
Temocillin 6.9
Keppra 6.9
Malarone 6.9
Caspofungin 6.5
Seroquel 6.4
AMK 6.4
Miglustat 6.3
Crixivan 6.2
Crixivan 6.2
Perphenazine 6.2
Madopar 6.1
Crixivan 6.1
Modafinil 5.9
Tianeptine 5.6
Monosodium glutamate 5.6
Carbidopa 5.6
Ritalin 5.5
Colistin 5.5
Posaconazole 5.4
Donepezil 5.4
Pramipexole 5.2
Pramipexole 5.2
Atovaquone 5.1
Glucantime 5.1
Miltefosine 5.0
Prozac 5.0
Isradipine 4.9
Spectrum 4.9
Geranium 4.9
Ceftazidime 4.8
Mezlocillin 4.8
IPD 4.7
Apomorphine 4.7
Vitamin B12 4.6
Duloxetine 4.6
Mirtazapine 4.6
DM1 4.6
Piracetam 4.5
Flunitrazepam 4.4
MDS 4.4
Trimethoprim-sulfamethoxazole 4.4
Zonisamide 4.3
MDM 4.2
AZT 4.2
ddI 4.1
Ketoconazole 3.9
AZT 3.9
Sinemet 3.9
TES 3.8
Meropenem 3.7
PPA 3.7
CFT 3.7
Metrizamide 3.7
Sulpiride 3.7
Vitamin B 3.6
Meropenem 3.6
Fluconazole 3.6
Depo-Provera 3.6
Honey 3.6
Domperidone 3.5
Trib 3.5
more...
Enzyme
DFPase 6.9
splicing endonuclease 6.6
DAP II 6.1
PWD 5.9
jararhagin 5.6
CYP46A1 5.5
propionyl-CoA carboxylase 4.5
propionyl-CoA carboxylase 4.5
TMT 4.3
cholinesterase 4.3
BIS 4.0
glucosylceramide synthase 4.0
SPT 3.9
acetylcholinesterase 3.8
CDR 3.6
argininosuccinate synthetase 3.5
GCA 3.5
DAT 3.4
FAST 3.4
SPT 3.1
Rex 3.1
ADH 2.8
21-hydroxylase 2.7
beta-lactamase 2.7
PCP 2.6
transketolase 2.6
ceruloplasmin 2.2
ornithine transcarbamylase 2.2
tryptophan hydroxylase 2.1
AST 1.9
thioredoxin reductase 1.7
aspartate aminotransferase 1.5
ricin 1.3
topoisomerase 1.2
alanine aminotransferase 1.2
GSK 1.2
hexosaminidase 1.1
monoamine oxidase 1.1
ACE 1.1
MDR 0.8
cytochrome oxidase 0.8
P-glycoprotein 0.8
topoisomerase 0.8
hyaluronidase 0.8
alcohol dehydrogenase 0.7
laccase 0.7
creatine kinase 0.7
IKK 0.7
adenosine deaminase 0.6
adenosine deaminase 0.6
pyruvate kinase 0.6
hyaluronidase 0.3
caspase-1 0.3
ATP synthase 0.1
lysozyme 0.1
NOS 0.1
lactate dehydrogenase 0.1
MAP 0.1
alkaline phosphatase -0.0
DNA polymerase -0.1
gamma-glutamyl transpeptidase -0.2
glutathione reductase -0.3
tissue plasminogen activator -0.5
thromboplastin -0.8
protein kinase -0.8
focal adhesion kinase -0.9
renin -1.2
phospholipase C -1.2
adenylate cyclase -1.3
glutathione peroxidase -1.5
glutathione S-transferase -1.5
ERK -1.6
catalase -1.8
proteasome -1.9
superoxide dismutase -1.9
reverse transcriptase -2.0
peroxidase -2.1
RNA polymerase -2.2
trypsin -2.4
ATPase -3.1
more...
Compound
Hydroquinidine 10.9
Halopemide 9.9
Trichothecin 9.5
Catharine 9.2
Ethyl gallate 9.2
Clopenthixol 9.0
Fludrocortisone acetate 8.9
Sodium cyclamate 8.8
Aurothioglucose 8.3
Melarsoprol 7.6
Mipafox 7.5
DDF 7.3
Rivastigmine 7.2
DBS 7.2
DMPD 7.2
PDQ 7.0
Nalorphine 6.9
Cyanocobalamin 6.9
CLTC 6.9
Bromazepam 6.8
Cefdinir 6.7
Diphenyl diselenide 6.6
Azlocillin 6.4
Mezlocillin 6.1
Oltipraz 6.1
Usnic acid 5.9
Methylphenidate 5.8
Felbamate 5.8
Ritalin 5.7
Trovafloxacin 5.7
Cefpirome 5.6
Fusidic acid 5.5
Enoxacin 5.4
SHA 5.4
C56 5.4
Aztreonam 5.4
Fosfomycin 5.4
Cefixime 5.4
Dansyl 5.4
Sanguinarine 5.4
Oxcarbazepine 5.3
Zonisamide 5.3
Benznidazole 5.3
Benznidazole 5.3
Benznidazole 5.3
Cefoxitin 5.2
NDS 5.2
Heroin 5.2
Foscarnet 5.1
Plumbagin 5.1
DCI 5.1
galanthamine 5.1
Geigy 5.1
Venlafaxine 5.1
Sertraline 5.0
Mesna 5.0
Eugenol 5.0
Soman 5.0
Amantadine 5.0
Eugenol 5.0
Amantadine 5.0
Saccharin 4.9
Moxalactam 4.9
Novobiocin 4.9
Amantadine 4.9
Mirtazapine 4.9
Ceftazidime 4.9
HMS 4.8
Selegiline 4.8
IPD 4.7
Levofloxacin 4.7
PZC 4.7
Memantine 4.7
Spiperone 4.7
Terbinafine 4.6
Alprazolam 4.6
Alba 4.6
Amitriptyline 4.6
Amantadine 4.6
TDP 4.6
more...