Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085632 (apathy)
 4,089 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CLUAP1 10.9
BEC1 9.9
Kv12.2 9.3
DC15 9.1
RAPGEF3 9.0
MRGPRD 8.9
YWHAQ 8.7
NPI 8.6
SHAP 8.5
LBX1 8.4
EXOC2 8.4
TSEN54 8.2
SCN9A 8.2
hSyn 8.1
IkappaB kinase complex-associated protein 8.0
cAMP-GEFII 7.8
CYP46 7.7
PRND 7.5
PRP-3 7.5
D3nf 7.4
DAOA 7.4
EIF2B5 7.3
FTD 7.3
EHMT1 7.3
STN 7.3
Nav1.3 7.3
DBS 7.2
GDS 7.2
MAPK6 7.1
mutS homolog 2 7.0
CBX8 6.9
Pgp1 6.9
LARS 6.9
Nav1.7 6.9
SLC5A1 6.9
Hos 6.9
DCTN1 6.9
CLTC 6.8
MDB 6.8
dynactin subunit 6.8
SCA17 6.7
SIX5 6.6
MCP-3 6.6
epsilon-sarcoglycan 6.6
ADAS 6.6
OFC 6.5
SKT 6.5
COXI 6.4
CHMP2B 6.4
GRN 6.4
SANS 6.4
C9orf72 6.4
PDHA1 6.4
CADASIL 6.4
chromosome 9 open reading frame 72 6.3
IL-1R2 6.3
VAPB 6.3
RagA 6.3
TE2 6.2
Dynactin 6.1
p92 6.1
HLA-Cw 6.1
CHRFAM7A 6.0
TAC1 6.0
SAPS 6.0
INCA 6.0
Complement C3 6.0
Jon 5.9
ARTEMIS 5.9
YWHAE 5.9
HDS 5.9
MOR-1 5.9
TRKA 5.8
mGlu3 5.8
alpha synuclein 5.8
Cholinesterase 5.8
PGRP 5.8
CUL3 5.8
CBX3 5.7
TDP-43 5.7
AES 5.7
G72 5.7
toll-like receptor 3 5.6
GABA-B receptor 5.6
Hu antigen R 5.6
MICE 5.6
M3 muscarinic receptor 5.5
P250 5.5
RORC 5.5
CHRNA7 5.4
MBNL1 5.4
MTG 5.3
ADL 5.3
Dopamine transporter 5.3
mGlu2 5.3
noradrenaline transporter 5.3
RAI 5.3
CAPE 5.2
T1R2 5.2
preprodynorphin 5.2
DCI 5.2
p150Glued 5.1
EMP 5.1
P210 5.1
DIVA 5.1
dysbindin 5.1
YWHAZ 5.0
voltage-gated sodium channel 5.0
P95 5.0
GTS 5.0
HRD 5.0
IFNAR 5.0
FCE 4.9
LPD 4.9
with Parkinsonism 4.9
MNS 4.9
panhypopituitarism 4.9
STG 4.8
DMPK 4.8
5-HT2C 4.8
SCA2 4.8
RDP 4.8
CS3 4.7
GTA 4.7
TPH1 4.7
B*15 4.7
EAD 4.7
propionyl-CoA carboxylase 4.7
Prion protein 4.7
FIM 4.7
Catechol-O-methyltransferase 4.6
NMS 4.6
RPR 4.6
CSF1R 4.6
Sho 4.6
TARDBP 4.6
DEM 4.6
HEX 4.6
ADN 4.6
HIP 4.6
FLU 4.6
NPC2 4.6
BAG 4.5
RDC 4.5
progranulin 4.5
DM1 4.5
T1R3 4.5
Tumor suppressor 4.5
BOP 4.5
transcobalamin II 4.4
NSP 4.4
4B) 4.4
FOG 4.4
GIP 4.4
D3R 4.4
MDS 4.4
putative function 4.4
interferon receptor 4.4
GRB2 4.4
muted 4.3
more...
Disease
pathological emotionality 12.9
Disorders of psychological development 12.9
Anosodiaphoria 11.9
Apathetic thyrotoxicosis 11.9
BDSD 11.9
witzelsucht 11.3
abulia 11.0
Frontal lobe degeneration 10.9
HMN7B 10.9
moria 10.3
Akinetic mutism 10.2
Poverty of speech 9.9
Fuchs' syndrome 9.9
Deluded 9.9
Infantile botulism 9.8
Periodic catatonia 9.8
BPSD 9.7
blunted affect 9.7
Fungal meningitis 9.6
panmyelophthisis 9.6
Uremic encephalopathy 9.5
Dementia in Parkinson's disease 9.5
Cortical laminar necrosis 9.3
SYNDROMES 9.2
mild memory disturbance 9.2
psychosomatic reaction 9.1
Pullorum disease 9.1
nihilistic delusion 9.0
temper tantrum 9.0
frontal lobe syndrome 9.0
Kleine-Levin syndrome 8.9
Fetal asphyxia 8.8
hypersexuality 8.7
Sleep attacks 8.7
quarrelsomeness 8.7
anosognosia 8.6
Stereotypic behavior 8.5
transcortical aphasia 8.5
onychogryphosis 8.5
simple schizophrenia 8.4
Abnormal behavior 8.4
Chronic depression 8.4
Frontal lobe 8.4
Performance anxiety 8.4
disinhibition 8.4
chronic organic brain syndrome 8.3
Congenital myotonic dystrophy 8.3
flat affect 8.3
impulse control disorder 8.3
Behavioral problems 8.3
sexual difficulty 8.3
sex addiction 8.3
Frontotemporal dementia 8.2
alcoholic encephalopathy 8.2
anhedonia 8.2
arteriosclerotic dementia 8.1
Lack of interest 8.1
sea sickness 8.0
Superior sagittal sinus thrombosis 8.0
Ehrlichia canis infection 8.0
hyperlysinemia 7.9
Frohlich 7.9
EPV 7.9
polioencephalitis 7.8
hallucinosis 7.8
depressive psychosis 7.8
delusions 7.8
derealization 7.7
amnesic syndrome 7.7
mutism 7.7
hallucinations 7.6
psychogenic amnesia 7.6
Hashitoxicosis 7.6
racing thoughts 7.6
pressured speech 7.5
Progressive Aphasia 7.5
GISA 7.5
solvent abuse 7.5
Kluver-Bucy syndrome 7.5
coenurosis 7.3
Limbic encephalitis 7.3
dysphoria 7.2
reactive depression 7.2
Corticobasal degeneration 7.2
T3 toxicosis 7.2
Substance dependence 7.1
battered child syndrome 7.1
specific developmental disorders 7.1
Prosopagnosia 7.1
delusions of persecution 7.0
nervous disorder 7.0
echolalia 7.0
despondency 7.0
psychoactive substance use disorders 7.0
psycho-organic syndrome 7.0
Refeeding syndrome 7.0
Neuroborreliosis 6.9
sexual sadism 6.9
chronic brain syndrome 6.9
Canine babesiosis 6.9
FTLD 6.9
Pick's disease 6.9
hepatosis 6.8
Severe depression 6.8
Severe malnutrition 6.8
sexual deviance 6.8
Laminitis 6.8
pathological gambling 6.8
nostalgia 6.8
acalculia 6.8
cognitive disorder 6.7
frigidity 6.7
paranoia 6.7
Narcissism 6.6
exhibitionism 6.6
SCA17 6.6
perception disorder 6.6
behavior disorder 6.6
psychasthenia 6.6
progressive supranuclear palsy 6.6
Pituitary gland 6.6
Pituitary gland 6.6
Pituitary gland 6.6
megalocytosis 6.6
neurobehavioral problems 6.5
glucose-galactose malabsorption 6.5
OFC 6.5
corneal degeneration 6.5
perseveration 6.5
Echinococcus granulosus infection 6.5
AIDS dementia complex 6.5
hypomania 6.5
Dementia with Lewy bodies 6.5
apraxia 6.5
agnosia 6.4
hypochondriasis 6.4
CADASIL 6.4
disorientation 6.4
obsessional personality 6.4
Brown tumor 6.4
fugue 6.4
VRSA 6.4
gambling problem 6.3
Fahr's disease 6.3
dementia 6.3
pseudobulbar palsy 6.3
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 6.3
Marchiafava-Bignami disease 6.3
encephalomyelopathy 6.3
anterograde amnesia 6.3
obsession 6.3
affective psychosis 6.3
akinesia 6.2
Cranial nerves 6.2
Cranial nerves 6.2
grandiosity 6.2
Acute mountain sickness 6.2
dysthymia 6.1
hereditary sensory neuropathy 6.1
paraphilia 6.1
more...
Symptom
apathy 12.9
dribbling saliva 12.9
amimia 11.0
clammy skin 9.1
Behavioral symptoms 8.9
personality change 8.6
Psychiatric symptoms 8.2
Positive and Negative Symptoms 7.9
hyperosmia 7.8
not coping 7.7
hypersomnia 7.7
motor symptom 7.6
Psychotic Symptoms 7.6
visual hallucination 7.6
carpopedal spasm 7.4
Hemiballism 7.3
bewilderment 7.1
agitation 7.0
prostration 7.0
staggering gait 6.8
bradykinesia 6.5
frequent urination 6.5
male puberty 6.5
auditory hallucination 6.5
adipsia 6.4
lassitude 6.4
Extrapyramidal symptoms 6.3
emaciation 6.2
localized edema 6.2
elevated mood 6.2
catatonia 6.1
drooling 6.1
meningism 6.1
forgetfulness 6.1
hopelessness 6.1
loss of taste 6.0
chorea 5.9
alexithymia 5.9
hyperesthesia 5.9
Decreased activity 5.9
memory loss 5.9
Signs and Symptoms 5.8
anorexia 5.8
lethargy 5.6
physical exhaustion 5.6
Deafferentation 5.5
sleepiness 5.5
hypalgesia 5.5
ataxic gait 5.4
impaired motor coordination 5.3
aphagia 5.3
Depressive symptoms 5.3
giddiness 5.3
giddiness 5.3
Opposition 5.2
hypertonia 5.2
blackout 5.1
decreased appetite 5.1
dysarthria 5.0
anal pain 5.0
polydipsia 5.0
aphonia 5.0
pallor 4.9
incoordination 4.9
asthenia 4.9
tremor 4.8
nasal discharge 4.8
hyperemesis gravidarum 4.8
consciousness disturbance 4.8
excessive sweating 4.8
ataxia 4.7
hypotonia 4.7
insomnia 4.6
No adverse effect 4.6
torticollis 4.6
fatigue 4.5
paresis 4.5
intention tremor 4.5
muscle rigidity 4.4
Poor sleep 4.4
clonus 4.4
constipation 4.4
anosmia 4.4
polyuria 4.3
dystonia 4.3
myoclonus 4.2
Sedation 4.1
loss of balance 4.1
stigma 4.1
tenesmus 4.0
tachypnea 3.9
weakness 3.9
eds 3.9
clumsiness 3.8
mental fatigue 3.7
Gastrointestinal symptoms 3.7
dysuria 3.7
hot flushes 3.6
cachexia 3.6
fasciculation 3.6
asynergy 3.6
vomiting 3.6
limb pain 3.5
cyanosis 3.4
photophobia 3.3
despair 3.3
dizziness 3.3
enuresis 3.2
paresthesia 3.2
hepatomegaly 3.2
livedo 3.2
epigastric pain 3.2
clubbing 3.1
diarrhea 3.0
dysesthesia 3.0
nausea 3.0
dry skin 2.9
twitching 2.9
blepharospasm 2.9
bone pain 2.9
fever of unknown origin 2.9
colic 2.9
Hudson 2.9
splenomegaly 2.8
discomfort 2.8
dyspnea 2.8
abnormal gait 2.8
hypoproteinemia 2.8
night sweats 2.7
dental pain 2.7
muscle stiffness 2.7
discomfort 2.6
Mills 2.6
headache 2.6
tingling 2.6
neck pain 2.6
tonic-clonic seizure 2.6
hemiplegia 2.5
exhaustion 2.5
bitter taste 2.5
physical appearance 2.3
thinning 2.3
menopausal symptoms 2.3
respiratory distress 2.3
ophthalmoplegia 2.2
functional recovery 2.2
pain 2.2
seizures 2.2
cerebellar ataxia 2.1
oliguria 2.1
Ill 2.1
hunger 2.0
hypothermia 2.0
acute pain 2.0
leg pain 1.9
blurred vision 1.9
tinnitus 1.8
hepatosplenomegaly 1.8
stridor 1.7
wheezing 1.7
more...
Drug
Bifemelane hydrochloride 9.9
Solganal 9.8
Clopenthixol 9.3
Percocet 8.9
Darvon 8.7
Foscavir 8.5
Equipoise 8.5
Istradefylline 8.2
Reminyl 8.0
Frontal 7.9
Exelon 7.8
FML 7.6
Exelon 7.6
Anidulafungin 7.5
DDF 7.3
DBS 7.2
PAPM/BP 7.0
Folic Acid 6.9
Dextropropoxyphene 6.9
Temocillin 6.9
Keppra 6.9
Malarone 6.9
Caspofungin 6.5
Seroquel 6.4
AMK 6.4
Miglustat 6.3
Crixivan 6.2
Crixivan 6.2
Perphenazine 6.2
Madopar 6.1
Crixivan 6.1
Modafinil 5.9
Tianeptine 5.6
Monosodium glutamate 5.6
Carbidopa 5.6
Ritalin 5.5
Colistin 5.5
Posaconazole 5.4
Donepezil 5.4
Pramipexole 5.2
Pramipexole 5.2
Atovaquone 5.1
Glucantime 5.1
Miltefosine 5.0
Prozac 5.0
Isradipine 4.9
Spectrum 4.9
Geranium 4.9
Ceftazidime 4.8
Mezlocillin 4.8
IPD 4.7
Apomorphine 4.7
Vitamin B12 4.6
Duloxetine 4.6
Mirtazapine 4.6
DM1 4.6
Piracetam 4.5
Flunitrazepam 4.4
MDS 4.4
Trimethoprim-sulfamethoxazole 4.4
Zonisamide 4.3
MDM 4.2
AZT 4.2
ddI 4.1
Ketoconazole 3.9
AZT 3.9
Sinemet 3.9
TES 3.8
Meropenem 3.7
PPA 3.7
CFT 3.7
Metrizamide 3.7
Sulpiride 3.7
Vitamin B 3.6
Meropenem 3.6
Fluconazole 3.6
Depo-Provera 3.6
Honey 3.6
Domperidone 3.5
Trib 3.5
Triad 3.5
Camp 3.4
OTC 3.4
Prednisolone 3.4
Norplant 3.3
Atenolol 3.2
DFP 3.1
ampicillin 3.1
PFA 2.9
OTC 2.9
Dakar 2.9
Doxycycline 2.8
Lactose 2.8
Horizon 2.7
PCP 2.7
DPA 2.6
CTC 2.6
ZnCl2 2.6
ZnCl2 2.6
Alliance 2.5
Portal 2.5
IPM 2.4
MgSO4 2.3
Bayer 2.3
VCR 2.3
Triclosan 2.3
TAC 2.3
Acacia 2.3
CSF 2.2
Gelatin 2.2
Norplant 2.1
Check 2.0
Estrogens 1.8
CDP 1.7
L-tyrosine 1.7
Clonidine 1.7
pyridoxal phosphate 1.6
ROC 1.6
G-CSF 1.6
ETA 1.5
Alanine 1.5
Vitamin A 1.4
ADM 1.3
Ethanol 1.3
MRC 1.2
niacin 1.0
Spectrum 0.9
ABC 0.8
citric acid 0.7
CTX 0.6
FAD 0.5
Histamine 0.5
CTX 0.5
CTX 0.4
EPA 0.1
caffeine 0.1
Leaf 0.1
ascorbate 0.0
MAP -0.0
lactose -0.1
ENT -0.1
nitroglycerin -0.2
Dial -0.4
Monit -0.6
Nephron -0.6
Gel -0.9
vitamin E -1.2
Nephron -1.2
ROS -1.3
NADH -1.5
Asthma -1.7
lysine -2.9
Dermatol -3.5
Cardiovasc -3.7
Enzyme
DFPase 6.9
splicing endonuclease 6.6
DAP II 6.1
PWD 5.9
jararhagin 5.6
CYP46A1 5.5
propionyl-CoA carboxylase 4.5
propionyl-CoA carboxylase 4.5
TMT 4.3
cholinesterase 4.3
BIS 4.0
glucosylceramide synthase 4.0
SPT 3.9
acetylcholinesterase 3.8
CDR 3.6
argininosuccinate synthetase 3.5
GCA 3.5
DAT 3.4
FAST 3.4
SPT 3.1
Rex 3.1
ADH 2.8
21-hydroxylase 2.7
beta-lactamase 2.7
PCP 2.6
transketolase 2.6
ceruloplasmin 2.2
ornithine transcarbamylase 2.2
tryptophan hydroxylase 2.1
AST 1.9
thioredoxin reductase 1.7
aspartate aminotransferase 1.5
ricin 1.3
topoisomerase 1.2
alanine aminotransferase 1.2
GSK 1.2
hexosaminidase 1.1
monoamine oxidase 1.1
ACE 1.1
MDR 0.8
cytochrome oxidase 0.8
P-glycoprotein 0.8
topoisomerase 0.8
hyaluronidase 0.8
alcohol dehydrogenase 0.7
laccase 0.7
creatine kinase 0.7
IKK 0.7
adenosine deaminase 0.6
adenosine deaminase 0.6
pyruvate kinase 0.6
hyaluronidase 0.3
caspase-1 0.3
ATP synthase 0.1
lysozyme 0.1
NOS 0.1
lactate dehydrogenase 0.1
MAP 0.1
alkaline phosphatase -0.0
DNA polymerase -0.1
gamma-glutamyl transpeptidase -0.2
glutathione reductase -0.3
tissue plasminogen activator -0.5
thromboplastin -0.8
protein kinase -0.8
focal adhesion kinase -0.9
renin -1.2
phospholipase C -1.2
adenylate cyclase -1.3
glutathione peroxidase -1.5
glutathione S-transferase -1.5
ERK -1.6
catalase -1.8
proteasome -1.9
superoxide dismutase -1.9
reverse transcriptase -2.0
peroxidase -2.1
RNA polymerase -2.2
trypsin -2.4
ATPase -3.1
ACS -3.3
Compound
Hydroquinidine 10.9
Halopemide 9.9
Trichothecin 9.5
Ethyl gallate 9.2
Catharine 9.2
Clopenthixol 9.0
Fludrocortisone acetate 8.9
Sodium cyclamate 8.8
Aurothioglucose 8.3
Melarsoprol 7.6
Mipafox 7.5
DDF 7.3
Rivastigmine 7.2
DBS 7.2
DMPD 7.2
PDQ 7.0
Nalorphine 6.9
Cyanocobalamin 6.9
CLTC 6.9
Bromazepam 6.8
Cefdinir 6.7
Diphenyl diselenide 6.6
Azlocillin 6.4
Oltipraz 6.1
Mezlocillin 6.1
Usnic acid 5.9
Methylphenidate 5.8
Felbamate 5.8
Ritalin 5.7
Trovafloxacin 5.7
Cefpirome 5.6
Fusidic acid 5.5
Enoxacin 5.4
SHA 5.4
C56 5.4
Aztreonam 5.4
Fosfomycin 5.4
Cefixime 5.4
Dansyl 5.4
Sanguinarine 5.4
Oxcarbazepine 5.3
Zonisamide 5.3
Benznidazole 5.3
Benznidazole 5.3
Benznidazole 5.3
Cefoxitin 5.2
NDS 5.2
Heroin 5.2
Foscarnet 5.1
Plumbagin 5.1
DCI 5.1
galanthamine 5.1
Venlafaxine 5.1
Geigy 5.1
Sertraline 5.0
Mesna 5.0
Eugenol 5.0
Soman 5.0
Amantadine 5.0
Eugenol 5.0
Amantadine 5.0
Saccharin 4.9
Moxalactam 4.9
Novobiocin 4.9
Amantadine 4.9
Mirtazapine 4.9
Ceftazidime 4.9
HMS 4.8
Selegiline 4.8
IPD 4.7
Levofloxacin 4.7
PZC 4.7
Memantine 4.7
Spiperone 4.7
Terbinafine 4.6
Alprazolam 4.6
Alba 4.6
Amitriptyline 4.6
Amantadine 4.6
TDP 4.6
Clozapine 4.5
5-FC 4.5
BOP 4.5
Vigabatrin 4.4
CoM 4.4
PAE 4.3
Linezolid 4.3
AIR 4.3
TES 4.2
XTT 4.2
MIC 4.2
TAR 4.2
DSM 4.2
Rifampicin 4.2
Poly(I:C) 4.2
CDT 4.2
Clonazepam 4.1
Zolpidem 4.1
EOS 4.1
Citalopram 4.1
Leucovorin 4.0
BAS 4.0
SPM 4.0
PSP 4.0
Quetiapine 4.0
Levetiracetam 4.0
Ketoconazole 3.9
Gossypol 3.9
Gossypol 3.9
Ifosfamide 3.9
Sulfamethoxazole 3.9
Tigecycline 3.9
Aripiprazole 3.9
Amphetamine 3.9
Amphetamine 3.8
Dopamine 3.8
Tobramycin 3.8
A 71 3.8
carbamyl phosphate 3.8
Bupropion 3.8
Polymyxin B 3.7
Vancomycin 3.7
Risperidone 3.7
Daptomycin 3.6
Neomycin 3.6
Gentamicin 3.6
AZT 3.6
PPA 3.5
Propionate 3.5
Tramadol 3.5
PPA 3.5
Streptomycin 3.5
Praziquantel 3.5
Cocaine 3.5
DAT 3.4
Ciprofloxacin 3.4
Prednisolone 3.4
5-HIAA 3.4
Tetrodotoxin 3.4
MBC 3.4
Amikacin 3.4
Voriconazole 3.4
MBC 3.4
Triclosan 3.3
Ketamine 3.3
hydroxyindoleacetic acid 3.3
3TC 3.3
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 3.3
Azole 3.3
SAH 3.3
LCR 3.3
Methamphetamine 3.2
Amphotericin B 3.2
LSD 3.2
4-methylphenyl 3.1
Olanzapine 3.1
MSG 3.1
Cbl 3.1
CCNU 3.1
Pima 3.1
more...