Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085631 (agitation)
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Human Gene/Protein
AE01 9.8
Dopamine receptor D3 9.4
ubiquitin-specific protease 21 8.8
PROSAP2 8.8
HIP3 8.8
BTBD9 8.6
SBK1 8.6
WBSCR17 8.4
Leukocyte Ig-like receptor 8.2
sal-like 4 8.2
ILT5 8.0
ADCYAP1 7.6
ALDC 7.6
NPI 7.5
glycine dehydrogenase 7.5
human leukocyte antigen B 7.4
PIPP 7.3
CL20 7.2
LADD 7.2
PDC2 7.1
KTN1 7.0
17-beta-hydroxysteroid dehydrogenase 6.9
PPSH 6.9
TDU 6.8
contactin-associated protein 2 6.8
HES3 6.8
sec23 6.8
CT9 6.7
L-glutaminase 6.6
26RFa 6.5
GPR103 6.5
ABC-C 6.5
PRN 6.4
GPR87 6.4
Kell protein 6.4
COM1 6.3
GABRA6 6.3
MPPA 6.2
TLL 6.2
Tur 6.2
APLP 6.2
CYP46 6.2
p17 protein 6.2
thyroid hormone receptor-associated protein 6.1
LILRA3 6.1
aspartyl aminopeptidase 6.1
DPP3 6.1
PG8 6.1
dopamine receptor D3 6.0
testes-specific protease 50 6.0
CGI 6.0
PRND 5.9
DCIP 5.9
PUM 5.9
acid-sensing ion channel 2 5.9
KFS 5.9
NPSR1 5.9
POM121 5.8
PAK3 5.8
Glutaredoxin-1 5.8
McLeod syndrome 5.8
GPR8 5.8
KAC 5.7
QRFP 5.7
Cholinesterase 5.7
OTR 5.7
HSL1 5.7
MRPP2 5.6
DVB 5.6
T49 5.6
SmF 5.6
CYB 5.6
voltage gated potassium channel 5.6
PS20 5.5
SSADH 5.5
DOD 5.4
B28 5.4
STY 5.4
MLC-2a 5.3
TESS 5.3
more...
Disease
Intermittent confusion 11.4
Auditory and visual hallucinations 10.8
Sundowning 10.7
Postictal delirium 10.4
BDSD 10.4
Butting 10.4
Pseudoparkinsonism 10.4
Agitated Depression 10.0
Acute mania 10.0
pressured speech 9.8
CBRS 9.8
Psychiatric emergencies 9.7
Acute confusional migraine 9.6
Semi-starvation 9.4
racing thoughts 9.4
DRRS 9.4
Frontal lobe degeneration 9.4
Other mental disorders 9.0
Drug-Induced Akathisia 9.0
Psychotic behavior 9.0
rapid reinstatement 9.0
Akathisia 9.0
Masked depression 8.9
chronic chorea 8.8
Episodic cluster headache 8.8
occupational and social impairment 8.8
Drug-induced delirium 8.8
Prepuce 8.8
organic personality syndrome 8.7
Alzheimer's disease with early onset 8.6
Hyperthymic 8.6
Drug-induced hyperkalemia 8.4
Deluded 8.4
Hoigne's syndrome 8.4
Periodic catatonia 8.2
disturbed concentration 8.2
BPSD 8.1
suicidal impulses 8.1
Acute psychosis 8.0
Hypertensive urgency 8.0
Frontal lobe epilepsy 8.0
emotional outburst 8.0
loosening of associations 8.0
delirium 7.9
Difficulty falling asleep 7.9
delusions of persecution 7.8
Negativism 7.8
Psychogenic polydipsia 7.7
KFS 7.7
Pubertal gynecomastia 7.6
paranoid reaction 7.6
hallucinations 7.5
Impulsive aggression 7.5
mixed bipolar disorder 7.5
Lucio phenomenon 7.5
Water intoxication 7.4
Foville syndrome 7.4
Iron deficiency without anemia 7.3
tangentiality 7.3
perceptual disturbance 7.3
Behavioral problems 7.3
compulsive neurosis 7.2
PCP abuse 7.2
extrapyramidal disorder 7.2
delusions of reference 7.2
disorientation 7.2
Sleep attacks 7.1
chronic paranoid schizophrenia 7.1
Small Intestine 7.1
delusions 7.1
alcohol withdrawal syndrome 7.1
Opioid Withdrawal 7.0
Isolated ACTH deficiency 7.0
Cognitive deterioration 7.0
restless legs syndrome 7.0
5-alpha reductase deficiency 7.0
involutional melancholia 7.0
anxiety attack 6.9
oxyuriasis 6.8
Mobitz type II atrioventricular block 6.8
more...
Symptom
agitation 11.4
Nocturnal agitation 11.4
Restlessness and agitation 11.4
Motor restlessness 9.4
clammy skin 8.6
Inspiratory stridor 8.6
Behavioral symptoms 8.3
decreased skin turgor 8.2
Sedation 8.2
upset stomach 8.1
Jitteriness 8.0
Morning headache 8.0
amimia 7.5
disturbed speech 7.4
Flaccid paralysis 7.2
Mental status changes 7.1
waxy flexibility 7.1
Thoracic pain 7.0
apathy 7.0
Respiratory abnormalities 7.0
Bladder distention 7.0
muscular incoordination 6.8
unable to sleep 6.8
dyslalia 6.8
Rebound insomnia 6.8
Extrapyramidal symptoms 6.8
insomnia 6.8
catatonia 6.7
Trembling 6.7
cold sweats 6.6
Hemicrania 6.5
Postoperative vomiting 6.5
Acute dyspnea 6.4
abdominal rigidity 6.4
excessive sweating 6.3
PAIN 6.3
hyperosmia 6.2
elevated mood 6.2
Psychiatric symptoms 6.2
personality change 6.1
clonus 6.0
Psychotic Symptoms 6.0
tachypnea 6.0
muscle rigidity 5.9
sleepiness 5.9
retching 5.8
feeling depressed 5.8
epigastric distress 5.8
Hemiballism 5.8
visual hallucination 5.8
sighing 5.8
growing pains 5.8
Positive and Negative Symptoms 5.7
hypersomnia 5.7
Central pain 5.7
micropsia 5.7
Beau's lines 5.6
prostration 5.6
Severe diarrhea 5.6
lassitude 5.5
frequent urination 5.5
Infantile colic 5.5
tremor 5.5
Gasping 5.5
jaw pain 5.4
GI irritation 5.4
Organ failure 5.4
lightheadedness 5.4
lethargy 5.3
Grimace 5.3
giddiness 5.3
giddiness 5.3
loss of equilibrium 5.2
staggering gait 5.2
tonic seizure 5.2
myoclonus 5.2
decreased appetite 5.2
drooling 5.1
dizziness 5.1
skin pain 5.1
more...
Drug
Crisnatol mesylate 11.4
Guancydine 10.4
Trimeprazine tartrate 9.8
Asiasarum root 9.8
Buprenorphine hydrochloride 9.6
Dextromethorphan hydrobromide 9.4
Revex 9.4
Disipal 9.4
Geodon 9.2
Sodium tetradecyl 9.0
Geodon 8.9
Clopenthixol 8.8
Lacrisert 8.8
Disipal 8.6
Serzone 8.6
Pipamperone 8.5
Propoxyphene napsylate 8.4
Olanzapine pamoate 8.4
Repetin 8.2
Angelica dahurica root 8.2
Domoic Acid 8.2
Myvacet 8.2
Risperdal Consta 8.2
Polysorbate 20 8.1
Magnesium phosphate 8.1
Tranxene 8.1
Ultiva 8.0
Ziprasidone hydrochloride 8.0
Bromperidol 7.9
Parecoxib sodium 7.9
Torecan 7.8
Ipecac syrup 7.8
Iletin II 7.8
Torecan 7.8
Ultane 7.8
Valpromide 7.8
Cnidii rhizoma 7.7
Precedex 7.7
Talwin 7.7
Baypress 7.5
Zuclopenthixol 7.5
Versed 7.4
Vivalan 7.4
Diethylpropion 7.3
Tranxene 7.3
Buspar 7.3
Platelet concentrate 7.3
Chlorpheniramine maleate 7.2
Dexmedetomidine hydrochloride 7.1
Valpromide 7.1
Parnate 7.1
Naltrexone hydrochloride 7.1
Sulthiame 7.1
Zotepine 7.0
Scutellaria root 7.0
Talwin 7.0
Gonadorelin 6.9
Paxil 6.9
Oxyphenbutazone 6.8
Oxyphenbutazone 6.7
Fluspirilene 6.7
Catapres 6.7
Nubain 6.7
Buspar 6.7
Nabilone 6.7
Moclobemide 6.7
Zaltoprofen 6.6
Corn starch 6.5
Tulobuterol 6.5
Paliperidone palmitate 6.5
RSM 6.5
Topamax 6.5
Lofexidine 6.4
dibasic calcium phosphate 6.4
Mirtazapine 6.4
Wheat starch 6.4
Concerta 6.3
Ludiomil 6.2
Cremophor RH40 6.2
Hypromellose 6.2
more...
Enzyme
tetrahydroprotoberberine cis-N-methyltransferase 10.4
protopine 6-hydroxylase 9.8
glycine dehydrogenase 7.7
glycine dehydrogenase 7.7
alpha-amino acid ester hydrolase 7.4
glycine dehydrogenase 7.0
linoleate diol synthase 6.9
DszB 6.7
inulinase 6.6
inulinase 6.5
1,3-propanediol dehydrogenase 6.5
tannase 6.3
benzaldehyde lyase 6.2
aspartyl aminopeptidase 6.1
lignin peroxidase 5.7
pyranose oxidase 5.4
manganese peroxidase 5.4
acetoacetate decarboxylase 5.3
PWD 5.3
azoreductase 5.2
TSO 5.1
benzoylformate decarboxylase 5.0
gluconate dehydrogenase 4.9
tyrosine phenol-lyase 4.9
acetolactate decarboxylase 4.7
stem bromelain 4.6
chlorophyllase 4.6
alpha-N-acetylglucosaminidase 4.5
DSR 4.5
versatile peroxidase 4.5
laccase 4.4
xylitol dehydrogenase 4.3
catechol oxidase 4.3
xylanase 4.3
dihydropyrimidinase 4.2
xylitol dehydrogenase 4.2
xylanase 4.2
cellulase 4.2
PNL 4.0
carbonyl reductase 3.9
CYP46A1 3.9
PDO 3.9
clotting enzyme 3.9
cellobiohydrolase 3.8
lipase 3.8
BIS 3.8
asparaginase 3.8
monoamine oxidase 3.7
nitrilase 3.7
beta-xylosidase 3.7
pectinase 3.7
cholinesterase 3.7
aspartase 3.6
feruloyl esterase 3.6
argininosuccinate synthetase 3.5
glucoamylase 3.5
DAT 3.4
SOR 3.4
CPL 3.3
glycine decarboxylase 3.2
fumarylacetoacetate hydrolase 3.2
succinic semialdehyde dehydrogenase 3.1
pectate lyase 3.1
acylase 3.1
penicillin acylase 3.1
beta-glucosidase 3.1
acetolactate synthase 3.1
porphobilinogen deaminase 3.1
disulfide reductase 3.0
chitosanase 2.9
cholesterol oxidase 2.9
acetylcholinesterase 2.9
pullulanase 2.9
isoamylase 2.8
glutaminase 2.8
apyrase 2.8
catechol O-methyltransferase 2.8
dextranase 2.7
prolyl endopeptidase 2.7
transaldolase 2.7
more...
Compound
Propyl oleate 11.4
Shale oils 11.4
2-Amino-5-phosphopentanoic acid 10.4
Elamol 10.4
3-bromobenzoic acid 9.8
3-bromobenzoic acid 9.8
Lavendamycin 9.8
Sultopride 9.7
Picrocrocin 9.4
Fluanisone 9.4
C16H32O2 9.4
2-iodopyridine 9.0
Selfotel 9.0
Loxapine 8.9
cinnamyl butyrate 8.8
Tegin 8.8
terephthaloyl dichloride 8.6
Clopenthixol 8.5
Acid Violet 17 8.4
Cresol Red 8.4
Chlorpromazine sulphoxide 8.4
Tetraethylenepentamine 8.2
Bromophos 8.2
C.I. Pigment Red 3 8.2
5-decyne 8.0
Galactonate 7.9
Diethylpropion 7.9
C9H9NO2 7.9
Torecan 7.8
4-iodobenzoic acid 7.8
Butanal 7.7
Orange OT 7.7
1-chloropyrene 7.7
Thiothixene 7.5
p-Synephrine 7.5
Cyclobenzaprine 7.5
Ziprasidone 7.4
Cefotaxime sodium 7.4
Lorazepam 7.3
Levomepromazine 7.3
1,3-dimethylcyclohexane 7.3
Metaxalone 7.3
1,3-dimethylcyclohexane 7.3
Trimeprazine 7.3
Valerenic acid 7.3
Trazodone 7.2
Molindone 7.2
1-bromohexadecane 7.2
Dihydrotachysterol 7.1
Trimethyltin chloride 7.0
Orphenadrine 7.0
Santonin 7.0
Ethyl oleate 7.0
butyl butyrate 7.0
1-benzothiophene 6.9
1,6-dichlorohexane 6.9
Gonadorelin 6.9
Terrein 6.9
Dexmedetomidine 6.9
methyl laurate 6.9
Ciprofloxacin hydrochloride 6.8
C2H4O2 6.8
1,2,3-trimethylbenzene 6.8
Prochlorperazine 6.8
Dicyclomine 6.8
1-benzylpiperazine 6.8
Methyl red 6.7
Nefazodone 6.7
Aripiprazole 6.7
Mescaline 6.7
Mirtazapine 6.6
Quetiapine 6.6
Olanzapine 6.6
Dezocine 6.6
3-hydroxypropanoic acid 6.6
Bupropion hydrochloride 6.6
Doxylamine 6.5
ethyl laurate 6.5
FK463 6.5
Phosphate ion 6.5
more...