Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0085631 (
agitation
)
12,064
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effects of local infusion of a 16 mM K+ solution or of a nociceptive stress on the release of somatostatin (
SRIF
) from the hypothalamus was measured in unanesthetized male rats implanted with a push-pull cannula in the median eminence. Although the baseline secretion rate of
SRIF
was increased in animals displaying
agitation
as a result of handling stress, both treatments induced fast doubling of
SRIF
release lasting for 15-30 min. Neither an equimolar Na+ infusion into the median eminence nor a similar K+ infusion into the 3rd ventricle had any affect on this release. The possible role of
SRIF
release in the mechanism of growth hormone inhibition following nociceptive stress is discussed.
...
PMID:In vivo release of somatostatin from rat median eminence after local K+ infusion or delivery of nociceptive stress. 614 8
