Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085631 (agitation)
 12,064 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In an international comparative study the symptomatology of depressive patients from psychiatric services in Addis Ababa, Ethiopia (N = 52) and in Mannheim, Federal Republic of Germany (N = 136) was investigated with the WHO Schedule for Standardized Assessment of Depressive Disorders (WHO/SADD). Controlled for differences in the sex-, age- and diagnostic-distribution of the two samples, depressive patients in Addis Ababa showed significantly more somatic symptoms, hypochondrias, psychomotor restlessness and delusions of reference and persecution, but markedly less feelings of guilt. Nevertheless, the same core of symptomatology was found to build in both samples the first and most important factor of 17, mainly psychological complaints. Only "feelings of guilt" did not belong to this core in Addis Ababa. In contrast to what is often believed to be the case in African patients, the more frequently expressed somatic complaints came in addition to, but did not replace the core-psychological symptomatology. The investigators stress the importance of a separate analysis of the frequencies of symptoms and of dimensions these symptoms build.
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PMID:[Culture specific or universal depressive diseases? Comparison of depressive symptoms of WHO/SADD (Standardized Assessment of Depressive Disorders) in Mannheim, West Germany and Addis Abeba, Ethiopia]. 244 31

We report a patient who experienced atypical symptoms in the course of electroconvulsive therapy (ECT). During ECT treatment patient experienced psychotic symptoms which should be differentiated with prolonged delirium and nonconvulsive status epilepticus. 46-year-old female was referred to hospital with a diagnosis of major depressive disorder with no psychotic features in the course of recurrent depression. Despite several changes of pharmacological treatment no improvement was achieved, therefore it was decided to initiate ECT. Physical and neurological examination revealed no deviations from the norm. The results of other tests (CT and EEG) were normal. 4 bilateral, bitemporal ECT procedures were performed. The course of each procedure was typical, the same doses of anesthetic medication and pulse dose was administered throughout all of the procedures. The duration of seizure was 32-40 s. Despite this mental symptoms observed during the course of the treatment differed from known to the authors from both their own experience and from literature. Delusions of reference, persecution, agitation, oneiric delusions and olfactory hallucinations which appeared after the 4th ECT session maintained for 14 days and resolved after treatment with olanzapine. To the best of our knowledge, this is the first report on delusions of reference and persecution, oneiric delusions and olfactory hallucinations associated with the course of ECT.
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PMID:Psychotic symptoms as a complication of electroconvulsive therapy - a case report. 2845 92