Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0085584 (
encephalopathy
)
18,178
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1146
MRI
1083
She
635
Mol
358
CSF
314
cytokine
216
axonal
215
albumin
166
prothrombin
156
insulin
151
MELAS
143
tRNA
138
GABA
127
ATP
126
X-linked
122
prion
114
Rett syndrome
113
IL-6
112
chronic renal failure
106
tumor necrosis factor
96
SCN1A
96
glial fibrillary acidic protein
93
cytochrome c oxidase
88
caspase-3
86
TNF
86
interferon
81
serum albumin
77
lipopolysaccharide
75
CD4
72
endoplasmic reticulum
71
tau protein
70
hemoglobin
68
interleukin-6
67
prion protein
66
gut
66
PrP
63
CDKL5
63
amyloid precursor protein
62
CA1
59
vasopressin
58
Pol
58
SARS
56
TDP-43
55
KCNQ2
53
MRS
53
sodium channel
53
neuroserpin
53
N-acetylaspartate
52
superoxide dismutase
50
NMDA receptor
46
creatine kinase
45
calcineurin
45
scratch
43
alkaline phosphatase
43
ETHE1
43
erythropoietin
42
olfactory
42
STXBP1
42
ATPase
41
aspartate aminotransferase
41
MECP2
41
myelin basic protein
41
IL-10
40
thyroid peroxidase
40
Gen
39
fibrinogen
39
TNF-alpha
38
SCN8A
38
GSH
38
nitric oxide synthase
37
HBA
37
peroxidase
35
neuron-specific enolase
35
lactate dehydrogenase
35
chemokine
35
ACTH
35
C-reactive protein
33
glutamic acid decarboxylase
33
lymphoid
33
MERRF
32
alanine aminotransferase
32
NMR
32
voltage-gated sodium channel
32
IFN
32
brain-derived neurotrophic factor
31
asymmetrical
31
glutamate receptor
31
IL-8
30
CO2
30
collagen
30
glutathione peroxidase
30
reserved
29
catalase
29
voltage-gated potassium channel
29
vascular endothelial growth factor
29
FDG
28
beta-endorphin
28
enolase
28
tyrosine hydroxylase
28
AST
28
cytochrome
28
glycoprotein
28
glucagon
27
renin
26
pyruvate dehydrogenase complex
26
HLA
26
pyruvate dehydrogenase
26
LDH
26
Bcl-2
25
transferrin
25
NADH
25
inducible nitric oxide synthase
25
mTOR
25
MIM
24
ADP
24
thyroglobulin
24
CA3
24
Neuroserpin
24
B12
24
tap
24
PRES
23
adrenocorticotropic hormone
23
glycine decarboxylase
22
DNA-binding protein
22
IL-1
22
TPO
22
arginine vasopressin
22
calcium channel
21
LPS
20
parathyroid hormone
20
somatostatin
20
glutamine synthetase
20
TNF receptor
20
galactosamine
20
acetylcholinesterase
20
KCNT1
19
synuclein
19
PNPO
19
TREX1
19
JAMA
19
DIC
19
growth hormone
19
SLC19A3
18
ADC
18
erythroid
18
ornithine transcarbamylase
18
CD8
18
ARX
18
ROS
18
P300
18
SAMHD1
17
cytochrome c
17
CD19
17
calcineurin inhibitor
17
factor V
17
S100B
17
citrin
17
ubiquitin
17
glucose transporter
17
threonine
17
more...
Disease
encephalopathy
18178
epilepsy
1455
stroke
1212
encephalitis
891
coma
798
hypertension
789
cirrhosis
757
dementia
726
lactic acidosis
670
hepatic encephalopathy
632
status epilepticus
503
Alzheimer's disease
490
ischemia
477
sepsis
466
Posterior
463
liver disease
458
sepsis
444
confusion
442
cognitive impairment
428
portal hypertension
414
cancer
394
fits
389
mitochondrial myopathy
380
HIV
362
diabetes
358
influenza
342
renal failure
334
Hashimoto's thyroiditis
327
developmental delay
326
cerebral palsy
323
depression
298
AIDS
269
virus infection
264
West
253
immunodeficiency
245
hypoglycemia
242
brain atrophy
237
leukoencephalopathy
229
tumor
229
brain edema
224
varices
222
hepatitis
218
multiple sclerosis
217
meningitis
213
myopathy
211
esophageal varices
211
coagulopathy
208
psychosis
208
mental retardation
205
peripheral neuropathy
204
MELAS
203
vasculitis
202
mental retardation
200
neuropathy
199
delirium
193
pneumonia
191
Reye's syndrome
191
eclampsia
172
blindness
171
Leigh syndrome
170
chronic liver disease
169
neurological disease
168
anemia
167
hemiparesis
162
cardiomyopathy
158
encephalomyelitis
156
polyneuropathy
154
infectious diseases
154
parkinsonism
150
mitochondrial disease
149
brain dysfunction
146
renal disease
145
MELAS
143
Creutzfeldt-Jakob disease
142
systemic lupus erythematosus
138
respiratory failure
135
preeclampsia
133
Parkinson's disease
131
hydrocephalus
131
chronic renal failure
129
hallucinations
128
Rett syndrome
128
Lennox-Gastaut syndrome
127
malnutrition
125
retinopathy
122
thrombocytopenia
121
vascular disease
120
autism
118
subarachnoid hemorrhage
114
scrapie
113
Acute liver failure
113
myelopathy
110
deafness
107
hepatocellular carcinoma
107
Lennox-Gastaut syndrome
107
lymphoma
106
herpes simplex
105
pertussis
104
metabolic disorder
104
acute renal failure
104
Syndrome
103
cerebral ischemia
103
heart failure
102
aphasia
102
rash
101
disseminated intravascular coagulation
97
leukemia
97
prematurity
95
cytomegalovirus
95
acute lymphoblastic leukemia
94
hepatitis B
93
migraine
93
myelitis
92
dengue
92
Binswanger
90
meningoencephalitis
90
hypertensive encephalopathy
89
optic atrophy
88
alcoholism
88
cerebral infarction
85
viral hepatitis
85
disorientation
84
uremia
83
thiamine deficiency
83
hyperglycemia
82
hypothyroidism
81
malaria
79
sensorineural hearing loss
79
Wernicke's encephalopathy
79
measles
78
autoimmune disease
78
spongiform encephalopathy
77
schizophrenia
77
dehydration
77
alcoholic cirrhosis
76
atherosclerosis
75
hyperbilirubinemia
74
movement disorder
74
tetraplegia
71
rare disease
71
SARS
70
Ohtahara syndrome
69
Infection
69
gastroenteritis
68
amyotrophic lateral sclerosis
67
hepatorenal syndrome
67
neonatal asphyxia
64
nystagmus
64
hepatitis C
64
lymphadenopathy
64
pancreatitis
63
dysplasia
61
carcinoma
61
neuroblastoma
60
myoclonus epilepsy
60
lupus
59
renal insufficiency
59
tuberculosis
59
aseptic meningitis
59
failure to thrive
58
more...
Symptom
seizures
3228
headache
800
hypothermia
594
ataxia
436
vomiting
337
hypotonia
292
myoclonus
283
weakness
255
diarrhea
197
tremor
181
dystonia
173
lethargy
158
sleepiness
151
nausea
133
anesthesia
129
abdominal pain
123
pain
120
dysarthria
109
fatigue
102
spasticity
98
cerebellar ataxia
98
ophthalmoplegia
95
respiratory distress
91
hemiplegia
88
agitation
83
dizziness
79
consciousness disturbance
75
hepatomegaly
59
collapse
58
asterixis
56
chorea
54
cough
53
memory loss
53
anorexia
48
splenomegaly
46
myalgia
45
insomnia
44
constipation
41
tonic-clonic seizure
41
Ill
38
dyspnea
38
paresthesia
37
paresis
37
hypertonia
37
neurological disability
36
paraparesis
35
nausea and vomiting
34
blurred vision
33
analgesia
31
pallor
31
vertigo
30
hepatosplenomegaly
29
functional recovery
26
tachypnea
25
spasm
25
apathy
24
syncope
24
oliguria
23
bradykinesia
22
partial seizure
22
cyanosis
21
erythema
20
catatonia
20
colic
18
hypercapnia
18
asthenia
17
anosmia
15
hyperoxia
15
clonus
15
chills
14
hypersomnia
14
ataxic gait
14
back pain
14
arthralgia
14
ketonuria
13
tinnitus
13
hypocapnia
13
discomfort
12
twitching
12
discomfort
12
tonic seizure
12
polydipsia
12
intestinal bleeding
12
thinning
12
polyuria
11
starvation
11
photophobia
11
muscle cramps
11
personality change
11
abnormal gait
11
cachexia
11
numbness
11
sore throat
10
angina
9
loss of taste
9
chest pain
9
hyperemesis gravidarum
9
Neurologic symptoms
9
epigastric pain
8
forgetfulness
8
clumsiness
8
shortness of breath
8
flushing
7
neck stiffness
7
stridor
7
neck pain
7
visual hallucination
7
athetosis
7
exhaustion
7
meningism
7
enuresis
7
bone pain
6
Involuntary Movement
6
livedo
6
hypoproteinemia
6
incoordination
6
tense
6
fasciculation
6
fever of unknown origin
6
Wind
5
Anoxia
5
Induced hypothermia
5
lightheadedness
5
muscle stiffness
5
emaciation
5
decreased appetite
4
facial droop
4
stigma
4
ENT
4
hemoptysis
4
rigors
4
low back pain
4
muscle rigidity
4
neuralgia
4
wheezing
4
abdominal discomfort
3
adipsia
3
auditory hallucination
3
periorbital edema
3
astasia
3
Decreased activity
3
metamorphopsia
3
excessive sweating
3
drooling
3
dental pain
3
dark urine
3
hunger
3
hyperemesis
3
Sedation
3
blepharospasm
3
pedal edema
3
Spastic
3
intention tremor
3
acute stress
3
regurgitation
3
rhinorrhea
3
rales
2
generalized rash
2
giddiness
2
giddiness
2
more...
Drug
CSF
317
Portal
52
lysine
41
Dial
30
Cardiovasc
30
Vitamin B
28
NADH
24
Tacrolimus
22
Dermatol
20
Phenytoin
19
ROS
18
Monit
18
ampicillin
16
pyridoxal phosphate
16
vitamin E
16
niacin
15
NH3
15
Methylene blue
15
ROC
14
Leaf
14
AZT
13
Albumin
13
AZT
13
caffeine
12
IL-2
12
Methylprednisolone
11
Nephron
11
ascorbate
10
Salicylate
10
CFS
10
Nephron
9
Frontal
9
lactose
8
CTX
8
PTH
8
citric acid
8
Acyclovir
8
Rifaximin
8
nitroglycerin
7
Sodium valproate
7
Oseltamivir
7
Serum albumin
7
Spectrum
7
Magnesium sulfate
7
Gabapentin
6
Propofol
6
Oxaliplatin
6
IFN-gamma
6
Gel
6
Ganciclovir
6
CPR
6
G-CSF
6
Pyridoxal phosphate
6
Ethanol
6
Prednisolone
6
Lanthanum carbonate
6
ABC
6
Fluorescein
6
Mectizan
5
TTC
5
Clonidine
5
Fluorescein
5
Rituximab
5
Histamine
5
THF
5
CAM
4
OTC
4
Theophylline
4
MAP
4
Glucagon
4
Mel B
4
Parkin
4
Parkin
4
DMAP
4
BH4
4
OTC
4
ENT
4
Ranitidine
4
Piracetam
4
Vitamin B12
4
Kenyan
3
Nitric Oxide
3
L-tyrosine
3
Alanine
3
Glutathione
3
Omeprazole
3
Fragment
3
Bevacizumab
3
Calcium hopantenate
3
CTX
3
DPA
3
Stiripentol
3
Rufinamide
3
Bumetanide
3
NAG
3
Valproic Acid
3
Leucovorin
3
EE2
3
Sodium benzoate
3
Metrizamide
3
IL-1ra
3
EPA
3
MDS
3
MRC
3
MOF
3
Terlipressin
2
Arsenic trioxide
2
Aprepitant
2
Vinorelbine
2
Imatinib
2
Desferal
2
DDAVP
2
DDAVP
2
TAT
2
ZnCl2
2
Growth hormone
2
GHRP
2
Indomethacin
2
Etoposide
2
LYMErix
2
ALA
2
CVA
2
TAC
2
Growth hormone
2
Terlipressin
2
Prednisone
2
Ipilimumab
2
Indocyanine green
2
Piperacillin
2
Ringer's solution
2
VCR
2
CTX
2
uPA
2
Cerezyme
2
p75
2
Sucralfate
2
ZnCl2
2
Isoniazid
2
Activin
2
Taxol
2
Fludarabine
2
Asparaginase
2
Sorafenib
2
Anakinra
2
Bezafibrate
2
Peppermint oil
2
Gleevec
2
Sevelamer
2
PFA
2
Asthma
2
Meconium
2
Spectrum
2
Phentolamine
2
Pregabalin
2
Galactose
2
Thyroglobulin
2
Sinemet
2
Everolimus
2
Iopromide
2
Pertussis vaccine
2
more...
Enzyme
complex I
90
thyroid peroxidase
72
aspartate aminotransferase
71
caspase-3
66
alanine aminotransferase
65
creatine kinase
61
superoxide dismutase
58
pyruvate dehydrogenase
50
ATPase
49
calcineurin
48
peroxidase
47
cytochrome oxidase
46
alkaline phosphatase
43
succinate dehydrogenase
43
lactate dehydrogenase
41
catalase
40
mitogen-activated protein kinase
30
glutathione peroxidase
30
reverse transcriptase
29
AST
28
enolase
28
acetylcholinesterase
28
acyl-CoA dehydrogenase
27
renin
26
pyruvate dehydrogenase
25
pyruvate dehydrogenase
25
ERK
24
tyrosine hydroxylase
22
tissue plasminogen activator
22
protein kinase
21
asparaginase
21
NO synthase
21
gamma-glutamyl transpeptidase
20
glutamine synthetase
20
CPT
18
alpha-ketoglutarate dehydrogenase
17
focal adhesion kinase
17
CPR
17
proteasome
16
cholinesterase
16
ATP synthase
16
sulfur dioxygenase
16
urease
16
urease
16
ACE
15
diaphorase
15
glycine decarboxylase
14
trypsin
14
ornithine transcarbamylase
13
monoamine oxidase
13
glutaryl-CoA dehydrogenase
13
transketolase
12
protein kinase C
12
argininosuccinate synthetase
12
luciferase
11
AMP-activated protein kinase
11
acyl-CoA dehydrogenase
11
diaphorase
10
arginase
10
lipase
10
pyruvate carboxylase
10
APC
10
thromboplastin
10
citrate synthase
10
phenylalanyl-tRNA synthetase
9
plasmin
9
glutamate dehydrogenase
9
glutamate dehydrogenase
9
alcohol dehydrogenase
9
glutamate dehydrogenase
9
sulfite oxidase
9
sulfite oxidase
9
transcriptase
8
thymidine phosphorylase
8
adenylate cyclase
8
neuraminidase
8
angiotensin-converting enzyme 2
8
caspase-1
8
ceruloplasmin
8
argininosuccinate lyase
8
thrombin
8
biotinidase
8
RNA polymerase
7
dihydropyrimidine dehydrogenase
7
choline acetyltransferase
7
endonuclease
7
phosphodiesterase
7
dihydropyrimidine dehydrogenase
7
acid phosphatase
7
glutaminase
7
AMPK
7
glutamate decarboxylase
7
GSK
7
DNA polymerase
7
AMPK
7
NADPH oxidase
6
glutathione S-transferase
6
NADPH-diaphorase
6
Alternating
6
MIP
6
P-glycoprotein
6
porphobilinogen deaminase
6
CPT
6
fumarase
6
CPT
6
adenylosuccinate lyase
6
caspase-9
6
RNase
6
aldehyde dehydrogenase
6
RNase
6
phospholipase C
6
NADH dehydrogenase
5
ADH
5
urokinase-type plasminogen activator
5
ACS
5
GABA transaminase
5
NADPH oxidase
5
PARP
5
BMT
5
phosphatidylinositol 3-kinase
5
aldehyde dehydrogenase
5
collagenase
5
NOS
5
BAL
5
sulfatase
5
arginyl-tRNA synthetase
5
cathepsin D
5
pantothenate kinase
5
CNPase
5
proteinase K
5
CEP
4
Protein 2
4
3-hydroxyacyl-CoA dehydrogenase
4
aldehyde dehydrogenase
4
glucocerebrosidase
4
NQO1
4
carbonic anhydrase
4
aldehyde dehydrogenase
4
succinic semialdehyde dehydrogenase
4
hexokinase
4
thymidine kinase
4
phospholipase A2
4
branched-chain alpha-keto acid dehydrogenase
4
isocitrate dehydrogenase
4
arylsulfatase A
4
methylenetetrahydrofolate reductase
4
dihydropteridine reductase
4
neutrophil elastase
4
caspase-8
4
propionyl-CoA carboxylase
4
aldehyde dehydrogenase
4
adenosine deaminase
4
adenosine deaminase
4
isocitrate dehydrogenase
4
T-protein
4
glutathione reductase
4
CYP3A4
4
methylenetetrahydrofolate reductase
4
PDE
4
glyoxalase II
3
more...
Compound
Clin
1446
Dec
1165
DNA
611
ammonia
570
oxygen
438
sodium
401
glucose
395
water
394
urea
259
His
246
calcium
235
glutamate
232
creatinine
199
leucine
187
aluminum
162
nitrogen
150
CO2
150
phosphate
147
glutamine
139
GABA
130
GABA
127
ATP
126
potassium
125
iron
113
arginine
107
nitric oxide
94
Valproic acid
88
TNF
86
ammonium
76
NH2
75
gamma-aminobutyric acid
75
tyrosine
72
methionine
70
hydrogen
67
galactose
64
ethanol
63
Phe
63
tryptophan
60
acetate
60
tryptophan
58
Neuronal
57
lysine
57
N-acetylaspartate
57
tryptophan
57
tryptophan
57
zinc
56
sulfate
56
Ile
55
valine
51
alanine
49
isoleucine
49
phosphorus
49
isoleucine
48
copper
47
salt
47
N-acetylcysteine
46
L-carnitine
46
NMDA
44
Lead
44
Cereb
42
GSH
40
manganese
40
GSH
40
ornithine
39
ornithine
39
ornithine
39
ornithine
39
ornithine
39
Ifosfamide
38
ACTH
38
cysteine
37
serine
37
Gly
34
Methotrexate
34
Valproic acid
34
Cardiol
33
coenzyme Q10
33
phosphocreatine
33
Thiamine
30
Dial
30
FK506
29
carbonate
29
NIDA
28
Lactate
27
ADP
27
noradrenaline
27
threonine
26
mercury
26
CoA
26
H2S
25
TBI
25
ANA
24
NADH
24
ANA
24
ADP
24
Thyroid
24
ADP
24
2-oxoglutarate
24
nicotinamide
23
hydroxyglutarate
23
vitamin D
22
iodine
22
DPH
22
folinic acid
21
hydroxyindoleacetic acid
21
Luminal
20
AMPA
20
homocysteine
20
Cyclosporine
20
Pyridoxine
20
nitrate
20
Bismuth
19
Glutamate
19
aldosterone
19
AZT
19
hydroxide
19
fluorine
19
Asp
19
5-FU
19
NAD
18
Lactulose
18
APAP
18
dUTP
18
DIC
18
L-DOPA
18
bromide
18
ubiquinone
17
Methylene blue
17
silver
17
proline
17
A 3
17
Optimal
16
toluene
16
Isoproterenol
16
Coenzyme Q10
16
cyanide
16
H2S
15
TSH
15
uridine
15
Sodium
15
STZ
15
molybdenum
15
Cefepime
15
octanoic acid
14
octanoic acid
14
octanoic acid
14
NAD
14
Insulin
14
octanoic acid
14
octanoic acid
14
methanol
14
pyrimidine
14
salicylic acid
14
pyrimidine
14
aspartic acid
13
caffeine
13
sodium chloride
13
PEG
13
EDTA
12
acetic acid
12
more...