Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085584 (encephalopathy)
18,178 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1146
MRI 1083
She 635
Mol 358
CSF 314
cytokine 216
axonal 215
albumin 166
prothrombin 156
insulin 151
MELAS 143
tRNA 138
GABA 127
ATP 126
X-linked 122
prion 114
Rett syndrome 113
IL-6 112
chronic renal failure 106
tumor necrosis factor 96
SCN1A 96
glial fibrillary acidic protein 93
cytochrome c oxidase 88
caspase-3 86
TNF 86
interferon 81
serum albumin 77
lipopolysaccharide 75
CD4 72
endoplasmic reticulum 71
tau protein 70
hemoglobin 68
interleukin-6 67
prion protein 66
gut 66
PrP 63
CDKL5 63
amyloid precursor protein 62
CA1 59
vasopressin 58
Pol 58
SARS 56
TDP-43 55
KCNQ2 53
MRS 53
sodium channel 53
neuroserpin 53
N-acetylaspartate 52
superoxide dismutase 50
NMDA receptor 46
creatine kinase 45
calcineurin 45
scratch 43
alkaline phosphatase 43
ETHE1 43
erythropoietin 42
olfactory 42
STXBP1 42
ATPase 41
aspartate aminotransferase 41
MECP2 41
myelin basic protein 41
IL-10 40
thyroid peroxidase 40
Gen 39
fibrinogen 39
TNF-alpha 38
SCN8A 38
GSH 38
nitric oxide synthase 37
HBA 37
peroxidase 35
neuron-specific enolase 35
lactate dehydrogenase 35
chemokine 35
ACTH 35
C-reactive protein 33
glutamic acid decarboxylase 33
lymphoid 33
MERRF 32
alanine aminotransferase 32
NMR 32
voltage-gated sodium channel 32
IFN 32
brain-derived neurotrophic factor 31
asymmetrical 31
glutamate receptor 31
IL-8 30
CO2 30
collagen 30
glutathione peroxidase 30
reserved 29
catalase 29
voltage-gated potassium channel 29
vascular endothelial growth factor 29
FDG 28
beta-endorphin 28
enolase 28
tyrosine hydroxylase 28
AST 28
cytochrome 28
glycoprotein 28
glucagon 27
renin 26
pyruvate dehydrogenase complex 26
HLA 26
pyruvate dehydrogenase 26
LDH 26
Bcl-2 25
transferrin 25
NADH 25
inducible nitric oxide synthase 25
mTOR 25
MIM 24
ADP 24
thyroglobulin 24
CA3 24
Neuroserpin 24
B12 24
tap 24
PRES 23
adrenocorticotropic hormone 23
glycine decarboxylase 22
DNA-binding protein 22
IL-1 22
TPO 22
arginine vasopressin 22
calcium channel 21
LPS 20
parathyroid hormone 20
somatostatin 20
glutamine synthetase 20
TNF receptor 20
galactosamine 20
acetylcholinesterase 20
KCNT1 19
synuclein 19
PNPO 19
TREX1 19
JAMA 19
DIC 19
growth hormone 19
SLC19A3 18
ADC 18
erythroid 18
ornithine transcarbamylase 18
CD8 18
ARX 18
ROS 18
P300 18
SAMHD1 17
cytochrome c 17
CD19 17
calcineurin inhibitor 17
factor V 17
S100B 17
citrin 17
ubiquitin 17
glucose transporter 17
threonine 17
more...
Disease
encephalopathy 18178
epilepsy 1455
stroke 1212
encephalitis 891
coma 798
hypertension 789
cirrhosis 757
dementia 726
lactic acidosis 670
hepatic encephalopathy 632
status epilepticus 503
Alzheimer's disease 490
ischemia 477
sepsis 466
Posterior 463
liver disease 458
sepsis 444
confusion 442
cognitive impairment 428
portal hypertension 414
cancer 394
fits 389
mitochondrial myopathy 380
HIV 362
diabetes 358
influenza 342
renal failure 334
Hashimoto's thyroiditis 327
developmental delay 326
cerebral palsy 323
depression 298
AIDS 269
virus infection 264
West 253
immunodeficiency 245
hypoglycemia 242
brain atrophy 237
leukoencephalopathy 229
tumor 229
brain edema 224
varices 222
hepatitis 218
multiple sclerosis 217
meningitis 213
myopathy 211
esophageal varices 211
coagulopathy 208
psychosis 208
mental retardation 205
peripheral neuropathy 204
MELAS 203
vasculitis 202
mental retardation 200
neuropathy 199
delirium 193
pneumonia 191
Reye's syndrome 191
eclampsia 172
blindness 171
Leigh syndrome 170
chronic liver disease 169
neurological disease 168
anemia 167
hemiparesis 162
cardiomyopathy 158
encephalomyelitis 156
polyneuropathy 154
infectious diseases 154
parkinsonism 150
mitochondrial disease 149
brain dysfunction 146
renal disease 145
MELAS 143
Creutzfeldt-Jakob disease 142
systemic lupus erythematosus 138
respiratory failure 135
preeclampsia 133
Parkinson's disease 131
hydrocephalus 131
chronic renal failure 129
hallucinations 128
Rett syndrome 128
Lennox-Gastaut syndrome 127
malnutrition 125
retinopathy 122
thrombocytopenia 121
vascular disease 120
autism 118
subarachnoid hemorrhage 114
scrapie 113
Acute liver failure 113
myelopathy 110
deafness 107
hepatocellular carcinoma 107
Lennox-Gastaut syndrome 107
lymphoma 106
herpes simplex 105
pertussis 104
metabolic disorder 104
acute renal failure 104
Syndrome 103
cerebral ischemia 103
heart failure 102
aphasia 102
rash 101
disseminated intravascular coagulation 97
leukemia 97
prematurity 95
cytomegalovirus 95
acute lymphoblastic leukemia 94
hepatitis B 93
migraine 93
myelitis 92
dengue 92
Binswanger 90
meningoencephalitis 90
hypertensive encephalopathy 89
optic atrophy 88
alcoholism 88
cerebral infarction 85
viral hepatitis 85
disorientation 84
uremia 83
thiamine deficiency 83
hyperglycemia 82
hypothyroidism 81
malaria 79
sensorineural hearing loss 79
Wernicke's encephalopathy 79
measles 78
autoimmune disease 78
spongiform encephalopathy 77
schizophrenia 77
dehydration 77
alcoholic cirrhosis 76
atherosclerosis 75
hyperbilirubinemia 74
movement disorder 74
tetraplegia 71
rare disease 71
SARS 70
Ohtahara syndrome 69
Infection 69
gastroenteritis 68
amyotrophic lateral sclerosis 67
hepatorenal syndrome 67
neonatal asphyxia 64
nystagmus 64
hepatitis C 64
lymphadenopathy 64
pancreatitis 63
dysplasia 61
carcinoma 61
neuroblastoma 60
myoclonus epilepsy 60
lupus 59
renal insufficiency 59
tuberculosis 59
aseptic meningitis 59
failure to thrive 58
more...
Symptom
seizures 3228
headache 800
hypothermia 594
ataxia 436
vomiting 337
hypotonia 292
myoclonus 283
weakness 255
diarrhea 197
tremor 181
dystonia 173
lethargy 158
sleepiness 151
nausea 133
anesthesia 129
abdominal pain 123
pain 120
dysarthria 109
fatigue 102
spasticity 98
cerebellar ataxia 98
ophthalmoplegia 95
respiratory distress 91
hemiplegia 88
agitation 83
dizziness 79
consciousness disturbance 75
hepatomegaly 59
collapse 58
asterixis 56
chorea 54
cough 53
memory loss 53
anorexia 48
splenomegaly 46
myalgia 45
insomnia 44
constipation 41
tonic-clonic seizure 41
Ill 38
dyspnea 38
paresthesia 37
paresis 37
hypertonia 37
neurological disability 36
paraparesis 35
nausea and vomiting 34
blurred vision 33
analgesia 31
pallor 31
vertigo 30
hepatosplenomegaly 29
functional recovery 26
tachypnea 25
spasm 25
apathy 24
syncope 24
oliguria 23
bradykinesia 22
partial seizure 22
cyanosis 21
erythema 20
catatonia 20
colic 18
hypercapnia 18
asthenia 17
anosmia 15
hyperoxia 15
clonus 15
chills 14
hypersomnia 14
ataxic gait 14
back pain 14
arthralgia 14
ketonuria 13
tinnitus 13
hypocapnia 13
discomfort 12
twitching 12
discomfort 12
tonic seizure 12
polydipsia 12
intestinal bleeding 12
thinning 12
polyuria 11
starvation 11
photophobia 11
muscle cramps 11
personality change 11
abnormal gait 11
cachexia 11
numbness 11
sore throat 10
angina 9
loss of taste 9
chest pain 9
hyperemesis gravidarum 9
Neurologic symptoms 9
epigastric pain 8
forgetfulness 8
clumsiness 8
shortness of breath 8
flushing 7
neck stiffness 7
stridor 7
neck pain 7
visual hallucination 7
athetosis 7
exhaustion 7
meningism 7
enuresis 7
bone pain 6
Involuntary Movement 6
livedo 6
hypoproteinemia 6
incoordination 6
tense 6
fasciculation 6
fever of unknown origin 6
Wind 5
Anoxia 5
Induced hypothermia 5
lightheadedness 5
muscle stiffness 5
emaciation 5
decreased appetite 4
facial droop 4
stigma 4
ENT 4
hemoptysis 4
rigors 4
low back pain 4
muscle rigidity 4
neuralgia 4
wheezing 4
abdominal discomfort 3
adipsia 3
auditory hallucination 3
periorbital edema 3
astasia 3
Decreased activity 3
metamorphopsia 3
excessive sweating 3
drooling 3
dental pain 3
dark urine 3
hunger 3
hyperemesis 3
Sedation 3
blepharospasm 3
pedal edema 3
Spastic 3
intention tremor 3
acute stress 3
regurgitation 3
rhinorrhea 3
rales 2
generalized rash 2
giddiness 2
giddiness 2
more...
Drug
CSF 317
Portal 52
lysine 41
Dial 30
Cardiovasc 30
Vitamin B 28
NADH 24
Tacrolimus 22
Dermatol 20
Phenytoin 19
ROS 18
Monit 18
ampicillin 16
pyridoxal phosphate 16
vitamin E 16
niacin 15
NH3 15
Methylene blue 15
ROC 14
Leaf 14
AZT 13
Albumin 13
AZT 13
caffeine 12
IL-2 12
Methylprednisolone 11
Nephron 11
ascorbate 10
Salicylate 10
CFS 10
Nephron 9
Frontal 9
lactose 8
CTX 8
PTH 8
citric acid 8
Acyclovir 8
Rifaximin 8
nitroglycerin 7
Sodium valproate 7
Oseltamivir 7
Serum albumin 7
Spectrum 7
Magnesium sulfate 7
Gabapentin 6
Propofol 6
Oxaliplatin 6
IFN-gamma 6
Gel 6
Ganciclovir 6
CPR 6
G-CSF 6
Pyridoxal phosphate 6
Ethanol 6
Prednisolone 6
Lanthanum carbonate 6
ABC 6
Fluorescein 6
Mectizan 5
TTC 5
Clonidine 5
Fluorescein 5
Rituximab 5
Histamine 5
THF 5
CAM 4
OTC 4
Theophylline 4
MAP 4
Glucagon 4
Mel B 4
Parkin 4
Parkin 4
DMAP 4
BH4 4
OTC 4
ENT 4
Ranitidine 4
Piracetam 4
Vitamin B12 4
Kenyan 3
Nitric Oxide 3
L-tyrosine 3
Alanine 3
Glutathione 3
Omeprazole 3
Fragment 3
Bevacizumab 3
Calcium hopantenate 3
CTX 3
DPA 3
Stiripentol 3
Rufinamide 3
Bumetanide 3
NAG 3
Valproic Acid 3
Leucovorin 3
EE2 3
Sodium benzoate 3
Metrizamide 3
IL-1ra 3
EPA 3
MDS 3
MRC 3
MOF 3
Terlipressin 2
Arsenic trioxide 2
Aprepitant 2
Vinorelbine 2
Imatinib 2
Desferal 2
DDAVP 2
DDAVP 2
TAT 2
ZnCl2 2
Growth hormone 2
GHRP 2
Indomethacin 2
Etoposide 2
LYMErix 2
ALA 2
CVA 2
TAC 2
Growth hormone 2
Terlipressin 2
Prednisone 2
Ipilimumab 2
Indocyanine green 2
Piperacillin 2
Ringer's solution 2
VCR 2
CTX 2
uPA 2
Cerezyme 2
p75 2
Sucralfate 2
ZnCl2 2
Isoniazid 2
Activin 2
Taxol 2
Fludarabine 2
Asparaginase 2
Sorafenib 2
Anakinra 2
Bezafibrate 2
Peppermint oil 2
Gleevec 2
Sevelamer 2
PFA 2
Asthma 2
Meconium 2
Spectrum 2
Phentolamine 2
Pregabalin 2
Galactose 2
Thyroglobulin 2
Sinemet 2
Everolimus 2
Iopromide 2
Pertussis vaccine 2
more...
Enzyme
complex I 90
thyroid peroxidase 72
aspartate aminotransferase 71
caspase-3 66
alanine aminotransferase 65
creatine kinase 61
superoxide dismutase 58
pyruvate dehydrogenase 50
ATPase 49
calcineurin 48
peroxidase 47
cytochrome oxidase 46
alkaline phosphatase 43
succinate dehydrogenase 43
lactate dehydrogenase 41
catalase 40
mitogen-activated protein kinase 30
glutathione peroxidase 30
reverse transcriptase 29
AST 28
enolase 28
acetylcholinesterase 28
acyl-CoA dehydrogenase 27
renin 26
pyruvate dehydrogenase 25
pyruvate dehydrogenase 25
ERK 24
tyrosine hydroxylase 22
tissue plasminogen activator 22
protein kinase 21
asparaginase 21
NO synthase 21
gamma-glutamyl transpeptidase 20
glutamine synthetase 20
CPT 18
alpha-ketoglutarate dehydrogenase 17
focal adhesion kinase 17
CPR 17
proteasome 16
cholinesterase 16
ATP synthase 16
sulfur dioxygenase 16
urease 16
urease 16
ACE 15
diaphorase 15
glycine decarboxylase 14
trypsin 14
ornithine transcarbamylase 13
monoamine oxidase 13
glutaryl-CoA dehydrogenase 13
transketolase 12
protein kinase C 12
argininosuccinate synthetase 12
luciferase 11
AMP-activated protein kinase 11
acyl-CoA dehydrogenase 11
diaphorase 10
arginase 10
lipase 10
pyruvate carboxylase 10
APC 10
thromboplastin 10
citrate synthase 10
phenylalanyl-tRNA synthetase 9
plasmin 9
glutamate dehydrogenase 9
glutamate dehydrogenase 9
alcohol dehydrogenase 9
glutamate dehydrogenase 9
sulfite oxidase 9
sulfite oxidase 9
transcriptase 8
thymidine phosphorylase 8
adenylate cyclase 8
neuraminidase 8
angiotensin-converting enzyme 2 8
caspase-1 8
ceruloplasmin 8
argininosuccinate lyase 8
thrombin 8
biotinidase 8
RNA polymerase 7
dihydropyrimidine dehydrogenase 7
choline acetyltransferase 7
endonuclease 7
phosphodiesterase 7
dihydropyrimidine dehydrogenase 7
acid phosphatase 7
glutaminase 7
AMPK 7
glutamate decarboxylase 7
GSK 7
DNA polymerase 7
AMPK 7
NADPH oxidase 6
glutathione S-transferase 6
NADPH-diaphorase 6
Alternating 6
MIP 6
P-glycoprotein 6
porphobilinogen deaminase 6
CPT 6
fumarase 6
CPT 6
adenylosuccinate lyase 6
caspase-9 6
RNase 6
aldehyde dehydrogenase 6
RNase 6
phospholipase C 6
NADH dehydrogenase 5
ADH 5
urokinase-type plasminogen activator 5
ACS 5
GABA transaminase 5
NADPH oxidase 5
PARP 5
BMT 5
phosphatidylinositol 3-kinase 5
aldehyde dehydrogenase 5
collagenase 5
NOS 5
BAL 5
sulfatase 5
arginyl-tRNA synthetase 5
cathepsin D 5
pantothenate kinase 5
CNPase 5
proteinase K 5
CEP 4
Protein 2 4
3-hydroxyacyl-CoA dehydrogenase 4
aldehyde dehydrogenase 4
glucocerebrosidase 4
NQO1 4
carbonic anhydrase 4
aldehyde dehydrogenase 4
succinic semialdehyde dehydrogenase 4
hexokinase 4
thymidine kinase 4
phospholipase A2 4
branched-chain alpha-keto acid dehydrogenase 4
isocitrate dehydrogenase 4
arylsulfatase A 4
methylenetetrahydrofolate reductase 4
dihydropteridine reductase 4
neutrophil elastase 4
caspase-8 4
propionyl-CoA carboxylase 4
aldehyde dehydrogenase 4
adenosine deaminase 4
adenosine deaminase 4
isocitrate dehydrogenase 4
T-protein 4
glutathione reductase 4
CYP3A4 4
methylenetetrahydrofolate reductase 4
PDE 4
glyoxalase II 3
more...
Compound
Clin 1446
Dec 1165
DNA 611
ammonia 570
oxygen 438
sodium 401
glucose 395
water 394
urea 259
His 246
calcium 235
glutamate 232
creatinine 199
leucine 187
aluminum 162
nitrogen 150
CO2 150
phosphate 147
glutamine 139
GABA 130
GABA 127
ATP 126
potassium 125
iron 113
arginine 107
nitric oxide 94
Valproic acid 88
TNF 86
ammonium 76
NH2 75
gamma-aminobutyric acid 75
tyrosine 72
methionine 70
hydrogen 67
galactose 64
ethanol 63
Phe 63
tryptophan 60
acetate 60
tryptophan 58
Neuronal 57
lysine 57
N-acetylaspartate 57
tryptophan 57
tryptophan 57
zinc 56
sulfate 56
Ile 55
valine 51
alanine 49
isoleucine 49
phosphorus 49
isoleucine 48
copper 47
salt 47
N-acetylcysteine 46
L-carnitine 46
NMDA 44
Lead 44
Cereb 42
GSH 40
manganese 40
GSH 40
ornithine 39
ornithine 39
ornithine 39
ornithine 39
ornithine 39
Ifosfamide 38
ACTH 38
cysteine 37
serine 37
Gly 34
Methotrexate 34
Valproic acid 34
Cardiol 33
coenzyme Q10 33
phosphocreatine 33
Thiamine 30
Dial 30
FK506 29
carbonate 29
NIDA 28
Lactate 27
ADP 27
noradrenaline 27
threonine 26
mercury 26
CoA 26
H2S 25
TBI 25
ANA 24
NADH 24
ANA 24
ADP 24
Thyroid 24
ADP 24
2-oxoglutarate 24
nicotinamide 23
hydroxyglutarate 23
vitamin D 22
iodine 22
DPH 22
folinic acid 21
hydroxyindoleacetic acid 21
Luminal 20
AMPA 20
homocysteine 20
Cyclosporine 20
Pyridoxine 20
nitrate 20
Bismuth 19
Glutamate 19
aldosterone 19
AZT 19
hydroxide 19
fluorine 19
Asp 19
5-FU 19
NAD 18
Lactulose 18
APAP 18
dUTP 18
DIC 18
L-DOPA 18
bromide 18
ubiquinone 17
Methylene blue 17
silver 17
proline 17
A 3 17
Optimal 16
toluene 16
Isoproterenol 16
Coenzyme Q10 16
cyanide 16
H2S 15
TSH 15
uridine 15
Sodium 15
STZ 15
molybdenum 15
Cefepime 15
octanoic acid 14
octanoic acid 14
octanoic acid 14
NAD 14
Insulin 14
octanoic acid 14
octanoic acid 14
methanol 14
pyrimidine 14
salicylic acid 14
pyrimidine 14
aspartic acid 13
caffeine 13
sodium chloride 13
PEG 13
EDTA 12
acetic acid 12
more...