Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0085584 (
encephalopathy
)
18,178
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The objective of this study was to investigate whether changes in Abeta and
ERAB
exist in the brain of diabetic mice, and to observe the effects of APP17 peptide. The numbers of neurons stained by APP17 peptide Abeta1-40 Abeta1-42 Abeta1-16 and
ERAB
antibodies in the brain of diabetic mice was increased compared with normal mice. Staining in APP17 peptide-protected mice was similar to normal mice. We conclude that increased Abeta1-42 and
ERAB
is an important cause of neuronal degeneration in diabetic
encephalopathy
. APP17 peptide retards neuronal degeneration by regulating the metabolism of Abeta.
...
PMID:beta-Amyloid and its binding protein in the hippocampus of diabetic mice: effect of APP17 peptide. 1171 78
