Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085584 (encephalopathy)
 18,178 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An 18-years-old girl suddenly became comatose and afterwards presented stlpor, complex hyperkinesias and aphonia lasting 15-20 days. The clinical picture was that of an acute encephalopathy which was found to be due to typhoid fever. Follow-up showed severe permanent memory impairment and some degree of mental deterioration, but no longer evidence of basal ganglia signs.
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PMID:[Typhoid encefalopathy followed by permanent memory defects (author's transl)]. 123 6

Bilateral vocal cord paralysis and absent laryngeal sensation are previously unrecognized sequelae for Reye's syndrome, a severe acute encephalopathy in children. Four patients were seen at varying periods ranging from 2 weeks to 5 years after their diagnosis of an episode of severe Reye's syndrome over a 20-year period at the Children's Hospital of Los Angeles (Calif). All of the patients had bilateral true vocal cord paralysis with absent laryngeal sensitivity that was documented at endoscopy. As many as 50% of survivors of severe Reye's syndrome have breathy voices or aphonia. It is suggested that some of these children may have vocal cord dysfunction that is not the result of intubation, and are at risk for aspiration and its dangerous sequelae. A vagal nuclear injury is theorized to explain the sensory motor dysfunction of the larynx in these children.
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PMID:Vocal cord paralysis and superior laryngeal nerve dysfunction in Reye's syndrome. 229 40