Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085580 (essential hypertension)
 14,686 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
adrenergic, beta-3-, receptor 11.1
lethal giant larvae homolog 2 (Drosophila) 11.1
hypertension associated protein 11.1
cholesteryl ester transfer protein, plasma 11.1
EHT 11.1
transmembrane protein 183A 10.1
C5orf23 10.1
CD164L2 10.1
Kelch-like protein 3 10.1
C4orf22 10.1
chloride channel Kb 9.8
FAM78B 9.5
Amyloid protein A 9.5
KIAA0789 9.5
alpha-adducin 9.2
OE-3 9.1
VAV3 protein 9.1
RENBP 9.1
ADD2 9.0
dermcidin isoform 2 8.8
PRKWNK4 8.8
Sodium/hydrogen exchanger 8.8
G-protein beta-3 subunit 8.8
GNB3 8.5
GOSR1 8.5
ATP1A1 protein 8.5
LRRC10 8.5
SCNN1D 8.5
ARHGAP28 8.5
adducin 1 8.3
CaM-KIIN 8.3
NHA2 8.3
RENIN 8.2
TRIC-A 8.2
NAIP protein 8.1
Kv6.3 8.1
NOX5 protein 8.1
SLC24A3 8.1
NHSL1 8.1
STK39 8.0
ADD3 8.0
renin binding protein 7.9
OE-2 7.9
HSD11 7.9
nuclear interaction partner of ALK 7.9
SMTN 7.9
aldehyde dehydrogenase 2 family 7.9
ADD1 7.9
SCNN1B 7.8
endoplasmic reticulum aminopeptidase 2 7.8
MBS85 7.8
SLC9A2 7.8
GS27 7.8
urinary kallikrein 7.7
renalase 7.6
GRK4 7.6
sorting nexin 5 7.5
AT1 receptor-associated protein 7.5
RASGEF1B 7.5
TGFBRAP1 7.5
UTS2 7.5
leucine aminopeptidase 3 7.5
prominin-2 7.5
LLGL2 7.5
NDUFC2 7.4
renin 7.3
aldosterone synthase 7.3
GPR83 7.3
GTF2IRD2 7.3
SLC6A18 7.3
PRA 7.2
ATP2B1 7.2
DBP 7.2
UAGT 7.2
SCN7A 7.2
CYP11B2 7.2
SBP 7.1
STX4 7.1
Salusin-beta 7.1
GOSR2 7.1
more...
Disease
Compensated cirrhosis 11.1
Labile essential hypertension 11.1
essential hypertension 11.1
Peripheral and visceral atherosclerosis 11.1
Transient hypertension of pregnancy 11.1
Carotid arteriosclerosis 11.1
Hypertensive renal failure 11.1
NIDDM3 10.1
NIDDM4 10.1
Renal parenchymal disease 10.1
adrenal hypertension 9.4
high renin hypertension 9.1
secondary hypertension 9.1
borderline hypertension 8.9
Alimentary obesity 8.8
Rebound hypertension 8.5
Renal vascular disease 8.5
Aase syndrome 8.5
white coat hypertension 8.4
benign hypertension 8.3
Liddle's syndrome 8.3
Chronic lower respiratory diseases 8.3
Glucocorticoid-suppressible hyperaldosteronism 8.3
aldosteronism 8.2
genetic hypertension 8.2
Gordon's syndrome 8.1
Bilateral renal artery stenosis 8.1
uncomplicated hypertension 8.0
renal hypertension 8.0
Aortic valve prolapse 7.9
Rheumatic valvular disease 7.9
Secondary hyperaldosteronism 7.9
Nephroangiosclerosis 7.9
Hypertensive emergency 7.8
nephrosclerosis 7.7
cardiophobia 7.6
NIDDM2 7.6
metabolic syndrome X 7.6
Serum potassium increased 7.5
malignant hypertension 7.5
Renovascular hypertension 7.5
Transient hypertension 7.4
neurocirculatory asthenia 7.4
neurogenic hypertension 7.4
late onset disorder 7.4
hypertensive retinopathy 7.4
Ectopic hamartomatous thymoma 7.3
renin-dependent hypertension 7.2
juxtaglomerular cell hyperplasia 7.2
NIDDM1 7.2
hypertensive nephropathy 7.1
Anaphylactoid reaction 7.1
IHG 7.1
PHA2 7.1
renal artery obstruction 7.1
ventricular hypertrophy 7.1
renal artery stenosis 7.0
familial hyperlipoproteinemia 7.0
Garre 6.9
Hypocalciuria 6.9
microalbuminuria 6.9
hypertensive heart disease 6.9
Non-dipping 6.8
Chronic pyelonephritis 6.8
systolic hypertension 6.8
new onset angina 6.7
Renal artery thrombosis 6.7
Atherosclerotic renal artery stenosis 6.7
FVR 6.7
diastolic hypertension 6.6
Goldblatt 6.6
Prehypertension 6.6
hypertension 6.5
hypertension in pregnancy 6.4
Transient myocardial ischemia 6.4
absent-mindedness 6.4
Maternal diabetes mellitus 6.4
Bright's disease 6.4
Orthostatic intolerance 6.4
adrenal adenoma 6.3
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Symptom
Epigastric discomfort 10.1
cardiovascular disability 7.3
High weight 6.8
vasovagal attacks 6.4
cardialgia 6.4
Multiple symptoms 6.3
stuffy nose 6.2
loss of taste 5.5
epigastric distress 5.5
pedal edema 5.3
lassitude 4.9
nocturnal polyuria 4.9
dizziness 4.9
exertional angina 4.7
peau d'orange 4.6
non-productive cough 4.5
bradypnea 4.4
rales 4.3
localized edema 4.3
cardiovascular impairment 4.3
asthenia 4.2
astasia 4.2
flushing 4.1
angina 3.8
No adverse effect 3.8
stomach pain 3.7
hypalgesia 3.6
alexithymia 3.5
giddiness 3.4
overweight 3.4
giddiness 3.4
muscle cramps 3.3
Stiffness 3.1
cough 3.1
lightheadedness 3.1
ketonuria 3.0
nasal congestion 2.9
headache 2.9
persistent cough 2.8
tingling 2.8
leg edema 2.7
urinary frequency 2.5
dystonia 2.4
consciousness disturbance 2.4
snoring 2.4
hot flushes 2.4
livedo 2.3
sleepiness 2.2
syncope 2.1
hot flashes 2.0
vertigo 2.0
spasm 1.9
fatigue 1.9
neuralgia 1.9
night sweats 1.9
constipation 1.8
Fluctuation 1.8
atypical chest pain 1.8
Depressive symptoms 1.7
forgetfulness 1.7
hyperoxia 1.5
chronic back pain 1.5
polyuria 1.5
torticollis 1.4
rigors 1.4
nausea 1.4
general problem 1.3
insomnia 1.3
clubbing 1.3
chest pain 1.3
oliguria 1.2
acute stress 1.2
neurological disability 1.2
hypersomnia 1.1
skin irritation 1.0
polydipsia 1.0
Ill 1.0
hypoproteinemia 0.9
dental pain 0.8
muscle stiffness 0.8
more...
Drug
Indenolol hydrochloride 11.1
Amlodipine maleate 11.1
Arotinolol hydrochloride 11.1
Paraaminohippurate 10.1
Mefruside 10.1
Lemildipine 10.1
Delapril hydrochloride 10.1
Clopamide 9.7
Tiamenidine 9.5
Tiodazosin 9.1
Accupril 9.1
Tripamide 9.1
Fenquizone 9.1
Pratosartan 8.8
Imidapril hydrochloride 8.8
Micardis 8.6
Guanadrel 8.5
Masoprocol 8.5
Aranidipine 8.5
Cilazapril 8.4
Trandate 8.4
Bendrofluazide 8.3
Accupro 8.3
Selectol 8.3
Masoprocol 8.3
Avapro 8.3
Darodipine 8.3
Cadralazine 8.2
Baypress 8.2
Indapamide 8.1
Hytrin 8.1
Estulic 8.1
Aldomet 8.0
Xipamide 8.0
Trandate 8.0
Dibenzyline 8.0
Alacepril 8.0
Isradipine 7.9
Cilnidipine 7.9
Manidipine hydrochloride 7.9
Losartan potassium 7.8
Hydrochlorothiazide 7.8
Sectral 7.8
Hytrin 7.8
Lofexidine 7.7
Trimepranol 7.7
Enalapril maleate 7.7
Lacidipine 7.7
Visken 7.7
Methacholine chloride 7.6
Minipress 7.6
Dyazide 7.6
Lacidipine 7.6
Indoramin 7.5
Chlorothiazide 7.5
Lercanidipine 7.5
Piretanide 7.4
Atenolol 7.4
Nebivolol 7.3
Indapamide 7.3
Cicletanine 7.3
Norvasc 7.3
Longgu 7.3
Felodipine 7.3
Perindopril 7.2
Potassium canrenoate 7.2
Arundic acid 7.2
Sectral 7.2
Concor 7.2
Olmesartan Medoxomil 7.2
Benidipine hydrochloride 7.2
Valsartan 7.1
Captopril 7.1
Metolazone 7.1
Olmesartan 7.1
Ramipril 7.1
Nadolol 7.0
Quinaprilat 7.0
Torasemide 7.0
Olmesartan medoxomil 7.0
more...
Enzyme
PGE2-9-ketoreductase 7.7
renin 7.3
PRA 7.1
ACE 6.2
AGT 6.0
kallikrein 6.0
MT 1 5.9
tissue kallikrein 5.4
prostacyclin synthase 5.3
11beta-hydroxysteroid dehydrogenase 5.3
CPA2 5.2
Delta6-desaturase 5.1
aminopeptidase B 4.9
GRK5 4.9
EC 4.4.1.5 4.8
PST 4.5
20beta-hydroxysteroid dehydrogenase 4.4
CPN 4.3
oxytocinase 4.2
GTI 4.2
PHT 4.1
angiotensin-converting enzyme 2 4.1
SRR 4.0
dopamine beta-hydroxylase 4.0
aminopeptidase A 3.9
prostasin 3.9
endothelin-converting enzyme 3.8
betaine-homocysteine methyltransferase 3.8
calcium pump 3.7
oxidosqualene cyclase 3.6
dCMP deaminase 3.6
methylenetetrahydrofolate reductase 3.6
MAP 3.6
methylenetetrahydrofolate reductase 3.6
alanine aminopeptidase 3.6
thromboxane synthase 3.5
Lod 3.5
methionine synthase reductase 3.4
argininosuccinate lyase 3.4
p-nitrophenylphosphatase 3.4
beta-secretase 3.3
chymase 3.3
SCP 3.3
branched-chain aminotransferase 3.2
HSD 3.2
eEF2 kinase 3.2
PPH 3.2
SST 3.1
prostaglandin synthetase 3.0
PAH 3.0
PAT 2.9
fumarylacetoacetate hydrolase 2.9
ATPase 2.9
cholesterol acyltransferase 2.9
dimethylarginine dimethylaminohydrolase 2.8
phenylethanolamine N-methyltransferase 2.8
nicotinamide phosphoribosyltransferase 2.5
tissue plasminogen activator 2.5
branched-chain alpha-keto acid dehydrogenase 2.5
nitrilase 2.4
phospholipase A1 2.4
NO synthase 2.4
arylsulfatase 2.4
CD10 2.4
paraoxonase 2.3
12-lipoxygenase 2.3
choline kinase 2.3
proton-translocating ATPase 2.3
NPL 2.2
LPL 2.2
NADPH oxidase 2.1
paraoxonase 2.1
SPT 2.0
lipoprotein lipase 2.0
NADPH oxidase 2.0
meprin 2.0
1-hydroxylase 1.9
CD13 1.9
xanthine dehydrogenase 1.8
lysyl oxidase 1.8
more...
Compound
C10H12O2 8.8
Enalkiren 8.8
C10H12O2 8.8
Ro 42-5892 8.8
18-Oxocortisol 8.8
Guanadrel 8.5
Moexipril 8.4
Navidrex 8.4
Acebutolol 8.4
Candesartan cilexetil 8.2
Doxazosin 8.2
Chlorthalidone 8.1
Debrisoquin sulfate 8.1
18-Hydroxycortisol 8.1
Eprosartan 8.1
Canrenone 8.1
Terazosin 8.0
Minipress 8.0
Guanfacine 8.0
Etozolin 7.9
C10H14N2O 7.9
Dibenzyline 7.9
Hydrochlorothiazide 7.9
Enalapril 7.7
Bisoprolol 7.7
Metanephrine 7.6
Tienilic acid 7.6
Labetalol 7.6
Dihydralazine 7.6
Glycylproline 7.5
Quinapril 7.5
Fosinopril 7.5
Bendroflumethiazide 7.4
Perindopril 7.3
Benazepril 7.3
Nitrendipine 7.3
HC 3 7.3
Quinacrine mustard 7.3
LPR 7.2
Moxonidine 7.2
Ketanserin 7.2
Penbutolol 7.1
Eplerenone 7.1
Thiazide 7.1
Amlodipine 7.0
Epanolol 7.0
DBP 7.0
aldosterone 7.0
Urapidil 6.9
4 PA 6.9
Telmisartan 6.9
Hippuran 6.9
DBP 6.8
Betaxolol 6.8
Nicardipine 6.8
Carteolol 6.7
Nisoldipine 6.7
Rilmenidine 6.6
Normetanephrine 6.6
2,3-dinor-thromboxane 6.5
Carvedilol 6.5
methyl decanoate 6.5
Pindolol 6.5
Debrisoquine 6.4
Ritodrine hydrochloride 6.4
Metoprolol 6.4
Spironolactone 6.3
Triamterene 6.3
Metoprolol 6.3
Candesartan 6.3
Losartan 6.2
Guanabenz 6.2
Diltiazem 6.1
Diltiazem 6.1
Nifedipine 6.1
Irbesartan 6.0
Fenoldopam 5.9
Gallopamil 5.9
Bretylium tosylate 5.9
4-hydroxydebrisoquine 5.9
more...