Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0085580 (essential hypertension)
14,686 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein renin 2687 insulin 915 angiotensin II 847 Sep 816 albumin 313 ACE 278 calcium channel 276 Mol 255 Ang II 251 SBP 229 DBP 228 ATPase 212 HDL 193 angiotensinogen 184 atrial natriuretic peptide 166 kallikrein 145 Pol 137 chronic renal failure 132 angiotensin II receptor 131 bradykinin 116 urinary kallikrein 114 vasopressin 112 PRA 104 Mal 104 atrial natriuretic factor 103 EHT 99 angiotensin receptor 97 endothelin-1 97 beta 1 95 mineralocorticoid receptor 91 collagen 89 Renin 88 fibrinogen 87 AT1 83 nitric oxide synthase 82 C-reactive protein 82 sodium pump 81 parathyroid hormone 76 Angiotensin-converting enzyme 70 ACTH 67 ATP 62 natriuretic peptide 62 hemoglobin 59 aldosterone synthase 55 Cor 54 prolactin 52 GFR 49 beta-endorphin 48 leptin 47 CYP11B2 46 beta-thromboglobulin 46 ANOVA 43 endothelial nitric oxide synthase 43 MAP 42 proximal tubule 41 plasminogen activator inhibitor-1 41 ADP 40 AMP 40 thrombin 40 arginine vasopressin 39 ANP 39 vascular endothelium 37 cytokine 36 alpha-adducin 34 superoxide dismutase 34 sodium channel 34 CRP 34 adiponectin 34 ET-1 33 calcitonin 33 angiotensin I-converting enzyme 32 HSD2 31 AT1R 31 glucagon 30 AMN 30 MRI 30 Endothelin-1 29 tumor necrosis factor 28 GNB3 28 cyclooxygenase 27 more...

Disease essential hypertension 14686 hypertension 7254 diabetes 799 ventricular hypertrophy 690 stroke 645 obesity 562 renal disease 464 aldosteronism 434 cardiovascular disease 426 atherosclerosis 412 heart failure 347 secondary hypertension 294 myocardial infarction 272 renal failure 237 congestive heart failure 236 hyperinsulinemia 224 microalbuminuria 222 type 2 diabetes 213 proteinuria 204 SEM 203 coronary heart disease 203 coronary artery disease 175 myocardial ischemia 171 renal artery stenosis 167 chronic renal failure 155 Conn 154 metabolic syndrome 153 preeclampsia 149 pheochromocytoma 141 cold 134 borderline hypertension 132 diabetic nephropathy 125 glucose intolerance 124 depression 115 psychological stress 114 hyperlipidemia 111 adenoma 108 renal hypertension 104 dyslipidemia 101 renal insufficiency 98 ischemia 88 genetic hypertension 85 vascular disease 85 systolic hypertension 84 ATM 83 malignant hypertension 83 nephrosclerosis 82 renal impairment 82 white coat hypertension 73 acute myocardial infarction 69 hyperuricemia 69 sympathomimetic 69 hypercholesterolemia 68 heart disease 65 tumor 63 cancer 60 Cushing's syndrome 53 cardiovascular risk factor 51 hyperglycemia 48 chronic glomerulonephritis 47 cardiomyopathy 46 hypertrophic cardiomyopathy 45 asthma 45 hypertensive heart disease 44 glomerulonephritis 43 pyelonephritis 42 rash 41 arteriosclerosis 40 glomerulosclerosis 40 pulmonary hypertension 40 retinopathy 39 uncomplicated hypertension 35 xerostomia 35 plaque 35 obstructive sleep apnea 34 adrenal hyperplasia 33 type 1 diabetes 33 eclampsia 31 Liddle's syndrome 30 AMN 30 more...

Symptom headache 193 angina 137 overweight 130 dizziness 130 cough 93 fatigue 90 pain 56 flushing 52 anesthesia 34 nausea 28 sleepiness 28 diarrhea 23 asthenia 22 dystonia 21 weakness 20 chest pain 19 syncope 18 constipation 17 discomfort 16 discomfort 16 vomiting 15 spasm 13 vertigo 13 insomnia 12 dyspnea 12 seizures 10 Ill 10 abdominal pain 9 alexithymia 9 exhaustion 9 exertional angina 9 loss of taste 8 collapse 8 snoring 7 anorexia 7 tremor 7 erythema 7 hyperoxia 7 rales 6 acute stress 5 agitation 5 arthralgia 5 myalgia 5 tingling 4 pedal edema 4 shortness of breath 4 nasal congestion 4 Stiffness 4 polyuria 4 muscle cramps 4 regurgitation 4 hypothermia 4 lassitude 4 stuffy nose 3 numbness 3 non-productive cough 3 low back pain 3 tinnitus 3 urinary frequency 3 dysarthria 3 hypercapnia 3 nausea and vomiting 3 ataxia 3 stomach pain 3 hot flushes 3 Depressive symptoms 3 back pain 3 neuralgia 3 Wind 2 livedo 2 lightheadedness 2 persistent cough 2 wheezing 2 night sweats 2 cachexia 2 nocturnal polyuria 2 polydipsia 2 cardialgia 2 oliguria 2 paresis 2 more...

Drug Cardiovasc 711 Captopril 144 Nephron 94 Angiotensin II 71 Atenolol 64 Nephron 56 Clonidine 54 MAP 44 nitroglycerin 44 Hydrochlorothiazide 40 Ouabain 37 Monit 31 ascorbate 31 Valsartan 30 Isradipine 29 Ramipril 27 Indapamide 26 Felodipine 26 Dial 25 Indapamide 24 Cilazapril 22 Perindopril 22 Nebivolol 20 caffeine 18 lysine 17 PTH 16 vitamin E 15 Olmesartan 13 Amiloride 13 Indomethacin 13 Amiloride 13 Coral 12 ETA 12 Chlorothiazide 11 Lacidipine 11 Aliskiren 11 ROC 11 Cilnidipine 10 Nadolol 10 Lacidipine 10 ICI 9 Methyldopa 9 Timolol 9 Diurnal 8 Inderal 8 NADH 7 Isoptin 7 Albumin 7 Dermatol 7 NAG 7 Trandolapril 6 Bosentan 6 Triclosan 6 Bosentan 6 Cicletanine 6 Gel 6 Torasemide 6 Losartan potassium 6 Fenoldopam 5 Enalapril maleate 5 CaCl2 5 ROS 5 CaCl2 5 CaCl2 5 Vitamin E 5 Lercanidipine 5 Indoramin 5 Olmesartan medoxomil 5 HCH 5 Timolol maleate 4 EPA 4 Dibenzyline 4 Micardis 4 Piretanide 4 Reserpine 4 Timoptol 4 Nitric Oxide 4 Alprenolol 4 citric acid 4 APM 4 more...

Enzyme renin 2687 ACE 619 ATPase 226 kallikrein 173 PRA 104 superoxide dismutase 43 MAP 42 NO synthase 39 thrombin 38 protein kinase C 38 tissue plasminogen activator 30 catalase 24 phospholipase C 24 CD10 24 tissue kallikrein 24 11beta-hydroxysteroid dehydrogenase 23 adenylate cyclase 23 AGT 23 NADPH oxidase 22 protein kinase 21 trypsin 20 mitogen-activated protein kinase 19 NADPH oxidase 19 ERK 17 PAH 16 luciferase 16 HSD 15 GRK5 15 lipoprotein lipase 13 methylenetetrahydrofolate reductase 12 tyrosine hydroxylase 12 glutathione peroxidase 12 methylenetetrahydrofolate reductase 12 phosphodiesterase 11 monoamine oxidase 10 dopamine beta-hydroxylase 10 guanylate cyclase 10 alkaline phosphatase 10 NOS 10 aspartate aminotransferase 10 PST 9 lactate dehydrogenase 9 peroxidase 9 xanthine oxidase 8 angiotensin-converting enzyme 2 8 alanine aminotransferase 8 phospholipase A2 7 gamma-glutamyl transpeptidase 7 prostacyclin synthase 7 cholesterol acyltransferase 7 endonuclease 7 focal adhesion kinase 7 prostaglandin synthetase 7 chymase 6 CAD 6 CAD 6 CAD 6 calcium pump 6 glucose-6-phosphate dehydrogenase 6 APC 6 lysozyme 6 CD13 6 acetylcholinesterase 6 proteasome 5 PGE2-9-ketoreductase 5 ceruloplasmin 5 plasmin 5 thromboplastin 5 creatine kinase 5 reverse transcriptase 4 transcriptase 4 alanine aminopeptidase 4 paraoxonase 4 glutathione S-transferase 4 succinate dehydrogenase 4 ACS 4 paraoxonase 4 calcineurin 4 RNA polymerase 4 beta-secretase 4 more...

Compound Clin 2515 sodium 2355 aldosterone 1439 calcium 1231 Dec 1188 salt 870 potassium 827 glucose 767 Cardiol 573 creatinine 545 noradrenaline 476 water 343 acetate 331 nitric oxide 296 oxygen 264 DBP 228 DBP 228 DNA 207 Insulin 189 Angiotensin II 144 arginine 142 Sodium 126 Ang II 99 Nifedipine 95 prostacyclin 92 urea 92 Salt 90 Enalapril 86 PGE2 71 Hydrochlorothiazide 70 ACTH 68 phosphate 67 sodium chloride 67 Propranolol 65 ATP 62 Propranolol 61 nitrogen 59 cGMP 56 ADP 55 mercury 52 Adrenal 51 Ketanserin 51 Losartan 50 Verapamil 50 Dopamine 46 MAP 43 Mg2+ 42 Verapamil 42 AMP 41 ADP 40 Diltiazem 40 ADP 40 Diltiazem 40 LPR 39 Doxazosin 39 Amlodipine 38 Ouabain 38 5-HT 38 homocysteine 37 Norepinephrine 37 sulfate 35 Labetalol 35 cAMP 33 EDTA 33 EDTA 33 methionine 32 Nitrendipine 32 Nicardipine 31 Prazosin 31 hydrogen 30 CO2 30 nitrate 30 Metoprolol 30 Carvedilol 30 phosphorus 29 Metoprolol 29 vitamin D 29 Telmisartan 27 tyrosine 27 threonine 27 more...

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