Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0085580 (
essential hypertension
)
14,686
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cholesteryl ester transfer protein, plasma
11.1
lethal giant larvae homolog 2 (Drosophila)
11.1
adrenergic, beta-3-, receptor
11.1
EHT
11.1
hypertension associated protein
11.1
C5orf23
10.1
Kelch-like protein 3
10.1
C4orf22
10.1
CD164L2
10.1
transmembrane protein 183A
10.1
chloride channel Kb
9.8
FAM78B
9.5
Amyloid protein A
9.5
KIAA0789
9.5
alpha-adducin
9.2
RENBP
9.1
VAV3 protein
9.1
OE-3
9.1
ADD2
9.0
G-protein beta-3 subunit
8.8
dermcidin isoform 2
8.8
PRKWNK4
8.8
Sodium/hydrogen exchanger
8.8
GNB3
8.5
SCNN1D
8.5
GOSR1
8.5
LRRC10
8.5
ATP1A1 protein
8.5
ARHGAP28
8.5
CaM-KIIN
8.3
adducin 1
8.3
NHA2
8.3
RENIN
8.2
TRIC-A
8.2
NHSL1
8.1
SLC24A3
8.1
Kv6.3
8.1
NOX5 protein
8.1
NAIP protein
8.1
STK39
8.0
more...
Disease
Compensated cirrhosis
11.1
Peripheral and visceral atherosclerosis
11.1
Labile essential hypertension
11.1
Carotid arteriosclerosis
11.1
Hypertensive renal failure
11.1
Transient hypertension of pregnancy
11.1
essential hypertension
11.1
NIDDM4
10.1
Renal parenchymal disease
10.1
NIDDM3
10.1
adrenal hypertension
9.4
high renin hypertension
9.1
secondary hypertension
9.1
borderline hypertension
8.9
Alimentary obesity
8.8
Rebound hypertension
8.5
Aase syndrome
8.5
Renal vascular disease
8.5
white coat hypertension
8.4
benign hypertension
8.3
Liddle's syndrome
8.3
Chronic lower respiratory diseases
8.3
Glucocorticoid-suppressible hyperaldosteronism
8.3
aldosteronism
8.2
genetic hypertension
8.2
Gordon's syndrome
8.1
Bilateral renal artery stenosis
8.1
uncomplicated hypertension
8.0
renal hypertension
8.0
Rheumatic valvular disease
7.9
Nephroangiosclerosis
7.9
Aortic valve prolapse
7.9
Secondary hyperaldosteronism
7.9
Hypertensive emergency
7.8
nephrosclerosis
7.7
cardiophobia
7.6
NIDDM2
7.6
metabolic syndrome X
7.6
Serum potassium increased
7.5
malignant hypertension
7.5
more...
Symptom
Epigastric discomfort
10.1
cardiovascular disability
7.3
High weight
6.8
vasovagal attacks
6.4
cardialgia
6.4
Multiple symptoms
6.3
stuffy nose
6.2
loss of taste
5.5
epigastric distress
5.5
pedal edema
5.3
lassitude
4.9
nocturnal polyuria
4.9
dizziness
4.9
exertional angina
4.7
peau d'orange
4.6
non-productive cough
4.5
bradypnea
4.4
rales
4.3
localized edema
4.3
cardiovascular impairment
4.3
asthenia
4.2
astasia
4.2
flushing
4.1
angina
3.8
No adverse effect
3.8
stomach pain
3.7
hypalgesia
3.6
alexithymia
3.5
giddiness
3.4
overweight
3.4
giddiness
3.4
muscle cramps
3.3
Stiffness
3.1
cough
3.1
lightheadedness
3.1
ketonuria
3.0
nasal congestion
2.9
headache
2.9
persistent cough
2.8
tingling
2.8
more...
Drug
Amlodipine maleate
11.1
Arotinolol hydrochloride
11.1
Indenolol hydrochloride
11.1
Delapril hydrochloride
10.1
Paraaminohippurate
10.1
Lemildipine
10.1
Mefruside
10.1
Clopamide
9.7
Tiamenidine
9.5
Tiodazosin
9.1
Tripamide
9.1
Fenquizone
9.1
Accupril
9.1
Imidapril hydrochloride
8.8
Pratosartan
8.8
Micardis
8.6
Aranidipine
8.5
Masoprocol
8.5
Guanadrel
8.5
Cilazapril
8.4
Trandate
8.4
Masoprocol
8.3
Avapro
8.3
Bendrofluazide
8.3
Selectol
8.3
Accupro
8.3
Darodipine
8.3
Cadralazine
8.2
Baypress
8.2
Indapamide
8.1
Hytrin
8.1
Estulic
8.1
Xipamide
8.0
Trandate
8.0
Aldomet
8.0
Dibenzyline
8.0
Alacepril
8.0
Isradipine
7.9
Cilnidipine
7.9
Manidipine hydrochloride
7.9
more...
Enzyme
PGE2-9-ketoreductase
7.7
renin
7.3
PRA
7.1
ACE
6.2
AGT
6.0
kallikrein
6.0
MT 1
5.9
tissue kallikrein
5.4
prostacyclin synthase
5.3
11beta-hydroxysteroid dehydrogenase
5.3
CPA2
5.2
Delta6-desaturase
5.1
aminopeptidase B
4.9
GRK5
4.9
EC 4.4.1.5
4.8
PST
4.5
20beta-hydroxysteroid dehydrogenase
4.4
CPN
4.3
oxytocinase
4.2
GTI
4.2
PHT
4.1
angiotensin-converting enzyme 2
4.1
SRR
4.0
dopamine beta-hydroxylase
4.0
aminopeptidase A
3.9
prostasin
3.9
endothelin-converting enzyme
3.8
betaine-homocysteine methyltransferase
3.8
calcium pump
3.7
dCMP deaminase
3.6
oxidosqualene cyclase
3.6
methylenetetrahydrofolate reductase
3.6
MAP
3.6
methylenetetrahydrofolate reductase
3.6
alanine aminopeptidase
3.6
thromboxane synthase
3.5
Lod
3.5
methionine synthase reductase
3.4
argininosuccinate lyase
3.4
p-nitrophenylphosphatase
3.4
more...
Compound
18-Oxocortisol
8.8
Ro 42-5892
8.8
C10H12O2
8.8
C10H12O2
8.8
Enalkiren
8.8
Guanadrel
8.5
Moexipril
8.4
Navidrex
8.4
Acebutolol
8.4
Candesartan cilexetil
8.2
Doxazosin
8.2
Chlorthalidone
8.1
Debrisoquin sulfate
8.1
Eprosartan
8.1
18-Hydroxycortisol
8.1
Canrenone
8.1
Terazosin
8.0
Minipress
8.0
Guanfacine
8.0
Etozolin
7.9
Dibenzyline
7.9
C10H14N2O
7.9
Hydrochlorothiazide
7.9
Enalapril
7.7
Bisoprolol
7.7
Tienilic acid
7.6
Metanephrine
7.6
Labetalol
7.6
Dihydralazine
7.6
Glycylproline
7.5
Quinapril
7.5
Fosinopril
7.5
Bendroflumethiazide
7.4
Perindopril
7.3
Benazepril
7.3
Nitrendipine
7.3
HC 3
7.3
Quinacrine mustard
7.3
LPR
7.2
Moxonidine
7.2
more...