Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085580 (essential hypertension)
 14,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Spontaneously hypertensive rats (SHR), salt-resistant (SRR), salt-sensitive (SSR), and Sprague-Dawley DOC-salt nephrectomized rats were tested by evaluation of tritiated norepinephrine uptake and blood pressure with diets containing various amounts of sodium. Only Sprague-Dawley rats who had been both nephrectomized and given DOC on a high salt diet (8%) illustrated the elevated tritium excretion similar to that observed in human subjects with essential hypertension.
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PMID:Urinary tritium excretion following intravenous 3H-norepinephrine administration in hypertensive rats. 741 43