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Query: UMLS:C0085580 (essential hypertension)
 14,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Patients with association of peptic ulcer and essential hypertension were found to form a heterogeneous group. Examination of this patients' group made it possible to distinguish certain clinical variants of such an association. Patients who first developed essential hypertension and then peptic ulcer were established to have a severe pattern of essential hypertension, unmarked and little symptomatic clinical picture of peptic ulcer, to be characterized by proneness to the complicated disease course. These features together with vascular lesions identified in the gastric submucosal layer, running their course as hypertonic microangiopathies permit attribution of the indicated ulcerations to the group of symptomatic gastroduodenal ulcers. In cases of association of peptic ulcer and essential hypertension, hemiton that suppresses the processes of gastric secretion was found to be the drug of choice.
Mater Med Pol
PMID:Analysis of association of peptic ulcer and essential hypertension from the standpoint of the problem of concomitant pathology. A possible role of vascular factor in the genesis of ulcer formation. 130 77

The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension. No significant differences in the secretion of the hormones studied, as compared to the patients with the normal arterial blood pressure, were found. After nifedipine treatment no significant changes in the secretion of aldosterone, cortisol and growth hormone were observed despite a significant fall in the arterial blood pressure while there was a moderate stimulatory effect on renin secretion. The results obtained indicate that nifedipine has only small effect on the hormonal system of patients with essential hypertension.
Endokrynol Pol 1991
PMID:[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. 136 91

In 134 patients with essential hypertension 24-hour blood pressure ambulatory monitoring (ABPM) as well as traditional blood pressure measurements (casual BP) were performed. Maximal and mean whole-day systolic and diastolic blood pressure values in ABPM were compared with casual BP (using test t). The casual BP was also compared with mean systolic and diastolic blood pressure values calculated separately in three eight-hours periods of day. Maximal BP values in ABPM were significantly higher and mean significantly lower than casual BP values. Blood pressure registered during work hours was closest to casual BP values. Blood pressure in the evening was similar to whole-day blood pressure mean. The results indicate, that automatic blood pressure monitoring performed in this period of day has the greatest diagnostic value because it could be free from "white coat hypertension" syndrome.
Kardiol Pol 1992 Sep
PMID:[Primary arterial hypertension. 24-hour recording or casual blood pressure measurement?]. 147 68

Insulinemia in patients with essential hypertension and normal glucose tolerance was assessed. The study involved 25 patients divided into subgroups according body weight and 9 of control subjects. It was found, that hyperinsulinemia seen in hypertensive patients seems to be associated with obesity. Moreover, hyperinsulinemia does not depend primarily on hypersecretion of insulin but may reflect resistance to insulin and ab normal metabolism in the liver.
Pol Tyg Lek
PMID:[Insulin and C-peptide levels in patients with idiopathic arterial hypertension]. 148 31

We evaluated the effect of captopril treatment on left ventricular mass (LVM) and function in sustained mild-to-moderate primary hypertension. In 16 men aged 34.5 +/- 6.4 yrs. M-mode echo and pulsed wave Doppler recordings were obtained prior to and after 2 months captopril treatment (50-150 mg daily). No significant changes in heart rate, systolic blood pressure, ejection fraction, fractional shortening, cardiac output, LVM and Doppler-derived indices of mitral inflow were observed. Diastolic blood pressure measured during examination fell from 102.2 +/- 13.3 to 90.3 +/- 9 mmHg (p less than 0.026). No consistent correlations between catecholamines and indexes of left ventricular function were found. Two-month captopril therapy in mild-to-moderate hypertension results in diastolic blood pressure lowering with no effect on LVM or left ventricular function.
Kardiol Pol 1992 May
PMID:[Primary arterial hypertension. Treatment with captopril and function of the left heart ventricle, concentration of catecholamine in blood and activity of renin]. 162 7

Adrenaline, noradrenaline and dopamine excretion was investigated in essential hypertension (n = 20), atherosclerotic heart failure (n = 20, NYHA class II and III), chronic angina (n = 10) and in healthy controls, in four time intervals: between 600-1200, 1200-1800, 1800-2400, 2400-600. Fluorimetric method of Anton and Sayre was employed. In patients with essential hypertension the circadian rhythm of adrenaline, noradrenaline and dopamine excretion was maintained but in all time intervals excretion of dopamine was decreased. In individuals with congestive heart failure due to atherosclerosis and in patients with ischemic heart disease, physiological circadian rhythm of adrenaline and noradrenaline excretion was found to be abolished. This was not the case with dopamine excretion which was undisturbed.
Kardiol Pol 1992 Apr
PMID:[Hypertension, heart failure and angina pectoris. Diurnal rhythm of urinary excretion of catecholamines]. 164 Jun 65

An effect of normal and high sodium diet on the rate of sodium outflow rate through lymphocyte cell membranes was evaluated in patients with mild primary hypertension with normal value of Na+ outflow rate index. It was found that high sodium value does not increase the value of this index in patients with mild primary hypertension but it does increase Na+ levels in lymphocytes. However, high sodium diet increases the value of this parameter in patients with mild primary hypertension with normal value of Na+ outflow rate through lymphocyte cell membranes and does not effect sodium level in the lymphocytes. According to the authors, high sodium diet in patients with normal renal function does not affect serum sodium levels.
Pol Tyg Lek
PMID:[Effect of normal and high sodium diet on the sodium outflow rate through lymphocyte cell membrane and lymphocyte sodium level in patients with mild primary hypertension]. 166 11

Sodium outflow rate through lymphocyte cell membranes was investigated in patients with primary hypertension with disturbed and normal sodium transport through these membranes during the treatment with hydrochlorothiazide, propranolol, clonidine or verapamil. It was found that hydrochlorothiazide increases total outflow rate of sodium ions through lymphocyte cell membranes and decreases its concentration in the lymphocytes but does not affect ouabain-dependent sodium outflow rate. It was also noted that verapamil increases total and ouabain-dependent sodium outflow rate through lymphocyte cellular membranes and decreases its lymphocyte levels.
Pol Tyg Lek
PMID:[Effect of selected hypotensive drugs on the rate of sodium outflow through lymphocyte cell membranes and sodium lymphocyte levels in patients with primary hypertension]. 166 12

A comparative studies on the effect of propranolol and acebutolol on blood pressure, cardiac function, blood serum lipids and lipoproteins were carried out in 48 patients with the primary hypertension double-blind method was applied. Tested drugs were given for 12 weeks. It was found, that both drugs are potent and comparable hypotensive agents normalizing blood pressure in the majority of treated patients. No significant difference in the effect on heart rate and adverse reactions has been noted. Acebutolol did not change lipid metabolism parameters whereas propranolol slightly but statistically significantly increased serum triglycerides.
Pol Tyg Lek
PMID:[Comparative studies on the effects of propranolol and acebutolol on blood pressure, serum lipids and lipoproteins in patients with primary hypertension]. 166 22

Plasma protein C and serine protease inhibitors together with some other hemostasis parameters have been determined in 60 patients with essential hypertension. Significant decrease in protein C and alpha 2-antiplasmin levels, increased fibrinogen, fibrinopeptide A, WF: Ag, plasminogen, and prolongation of euglobulin fibrinolysis time have been observed. Results indicate hypercoagulability and fibrinolysis defect in hypertensive patients.
Pol Tyg Lek
PMID:[Protein C and plasma serine protease inhibitors in patients with essential hypertension]. 166 85


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