Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085437 (bacterial meningitis)
 4,038 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
retinoic acid early transcript 1E 12.9
dynactin 4 10.9
EXOC6B 10.4
MYL5 10.4
TM-8 9.8
PRSP 9.4
FAIM3 9.4
Acetyl-CoA hydrolase 9.0
2'5' oligoadenylate synthetase 8.6
H. influenzae 8.6
receptor for advanced glycosylation end products 8.5
FAIM 8.2
chemokine (C-C motif) ligand 3 8.1
ITGAX 8.1
RALBP1 8.1
MSK2 7.9
ARHGAP5 7.9
FAIM2 7.9
lifeguard 7.9
transforming growth factor-beta-activated kinase 1 7.7
FTH 7.7
HLA-B52 7.6
acyloxyacyl hydrolase 7.6
TPO protein 7.6
CARD8 7.6
NG1 7.6
Complement protein 7.5
ELL2 7.4
CD 16 7.3
lactic acid dehydrogenase 7.3
IRAK-2 7.3
LTA4H 7.3
MNX1 7.3
ribosomal protein S20 7.2
Caspase-14 7.1
K100 7.1
CSF 7.1
CSF2 7.1
IQ motif containing GTPase activating protein 1 7.0
PISP 6.9
PRES 6.9
AP50 6.7
Beta-2-microglobulin 6.6
C2 protein 6.5
claudin 5 6.5
CSF1 6.4
CD14 antigen 6.4
CFLAR 6.4
SPN 6.3
heparin binding protein 6.3
TBM 6.2
RLIP76 6.2
white cell 6.2
mannan-binding protein 6.2
TEF-1 6.1
ITGB2 6.1
component D 6.1
CISH 6.0
DRw11 5.9
19A 5.9
HEXB 5.9
TNF-alpha converting enzyme 5.8
renal dipeptidase 5.8
DP3 5.8
PYGM 5.7
PEPT2 5.7
RBM 5.7
Granulocyte-colony stimulating factor 5.6
GBS 5.6
ORF 1 5.6
Decoy receptor 3 5.6
B-5 5.5
stromelysin-3 5.5
P97 5.5
GCH1 5.5
CASP1 5.5
Alpha-1-antitrypsin 5.4
heparin-binding protein 5.4
COL11A1 5.4
GCS 5.3
CXCL6 5.3
junctional adhesion molecule 5.3
DP5 5.3
O-acetyltransferase 5.3
variant 1 5.2
preproET-1 5.2
MMP8 5.2
apoptosis-associated speck-like protein containing a CARD 5.2
mannose binding lectin 5.2
NMB 5.2
L30 5.2
Adenosine deaminase 5.2
ITGA5 5.1
MRP8 5.1
C5a receptor 5.1
IFNAR2 5.1
MSK1 5.1
C5a anaphylatoxin 5.1
HLA-DRB 5.0
factor H 5.0
neurokinin 1 receptor 5.0
serum amyloid A protein 5.0
TIMP-4 5.0
lactotransferrin 5.0
C3G 4.9
Akt3 4.9
Nod1 4.9
IkappaB alpha 4.9
myosin light chain 2 4.9
GADD45B 4.9
IRAK4 4.8
MMP-8 4.8
Glutamic acid decarboxylase 4.8
CD87 4.8
gamma-amino butyric acid 4.8
CAPS 4.8
B55 4.8
CSK 4.8
NLRP1 4.7
DP2 4.7
CRP 4.7
CPZ 4.7
IgA1 4.7
sICAM-1 4.7
Sta 4.7
caspase 6 4.7
heat shock protein 72 4.6
ADH 4.6
PBP 4.6
TNF-a 4.6
NOD2 4.6
C-reactive protein 4.6
a proliferation-inducing ligand 4.6
MBL2 4.6
P45 4.5
S100A7 4.5
NST 4.5
CD66b 4.5
TLR2 4.5
CARD15 4.5
UTI 4.5
TLR1 4.5
DC2 4.4
Par3 4.4
polymeric immunoglobulin receptor 4.4
IL-1 beta 4.4
apoptosis-inducing factor 4.4
UDP-GlcNAc 4.4
beta-2-microglobulin 4.4
B7-H3 4.4
renal amyloidosis 4.3
Protein tyrosine phosphatase 4.3
wich 4.3
CL1 4.3
DAP12 4.3
TACE 4.3
cell division protein 4.3
BOS 4.3
EPM 4.3
brain-derived 4.3
more...
Disease
necrosis; cerebral 12.9
Other bacterial meningitis 12.9
bacterial meningitis 12.9
CMV radiculopathy 12.9
Staphylococcal meningitis 12.5
Sphenoidal sinusitis 11.9
Proteus meningitis 11.9
Recurrent bacterial meningitis 11.7
Suppurative labyrinthitis 11.6
viral meningitis 11.5
Klebsiella meningitis 11.5
Streptococcus pneumoniae meningitis 11.4
Pseudomonas meningitis 11.4
West Nile virus meningoencephalitis 11.4
Staphylococcus aureus meningitis 11.3
Streptococcal meningitis 11.1
Mycobacterium tuberculosis meningitis 11.1
Haemophilus influenzae meningitis 11.1
Neonatal meningitis 11.0
Salmonella meningitis 10.9
Escherichia coli meningitis 10.7
Haemophilus meningitis 10.7
Listeria meningitis 10.6
infectious meningitis 10.5
Anaerobic meningitis 10.4
HIB meningitis 10.4
gray syndrome 10.4
CNS candidiasis 10.4
meningococcal meningitis 10.3
bacterial CNS infection 10.1
Chemical meningitis 9.9
aseptic meningitis 9.7
meningitis 9.6
Fungal meningitis 9.6
Cytomegalovirus encephalitis 9.6
Neuroinfections 9.6
enterovirus meningitis 9.4
Salmonella sepsis 9.3
Cerebral vasculitis 9.2
Intracranial mass 9.1
ventriculitis 9.1
mumps meningitis 9.1
Subdural empyema 9.1
Disseminated strongyloidiasis 9.0
Tonsillar herniation 8.9
Ventriculitis 8.9
infectious encephalitis 8.9
Currarino triad 8.8
Herpes simplex 1 8.8
Neisseria infections 8.8
Meningocele 8.8
Tuberculous meningitis 8.8
petrositis 8.7
Streptococcus suis infection 8.7
ependymitis 8.6
ZD1 8.6
cholangiectasis 8.6
Necrotizing arteritis 8.5
Infections of the central nervous system 8.4
meningococcal infection 8.4
nervous system infection 8.4
Haemophilus 8.3
Viral encephalitis 8.3
Drug-induced immune thrombocytopenia 8.3
Shunt infection 8.3
labyrinthitis 8.2
primary amebic meningoencephalitis 8.2
meningococcemia 8.2
cerebral abscess 8.2
Salmonella enteritis 8.1
brain abscess 8.1
Vanishing bile duct syndrome 8.1
arteriosclerotic dementia 8.1
Enterococcal infections 8.1
Acute mastoiditis 8.0
Mollaret's meningitis 8.0
viral pharyngitis 7.9
Waterhouse-Friderichsen syndrome 7.9
Cerebrospinal fluid rhinorrhea 7.9
leptomeningitis 7.9
Gradenigo's syndrome 7.8
viral CNS infection 7.8
Bacterial sepsis 7.8
La Crosse encephalitis 7.8
Immunoblastic 7.8
Cavernous sinus thrombosis 7.8
meninges 7.8
Duodenal perforation 7.7
Hb SC disease 7.7
Communicating hydrocephalus 7.7
Acinetobacter infection 7.7
antibody deficiency syndrome 7.7
Rathke's cleft cyst 7.6
Haemophilus infections 7.6
Purpura fulminans 7.6
SIADH 7.5
Cortical blindness 7.5
Eosinophilic meningitis 7.5
Renal infarction 7.4
mastoiditis 7.4
HIV encephalitis 7.3
polyradiculitis 7.3
pneumocephalus 7.3
epiglottitis 7.3
febrile convulsions 7.3
cryptococcal meningitis 7.3
meningoencephalitis 7.2
Spinal cord infarction 7.2
Pneumococcal infection 7.2
complement deficiency 7.1
Intestinal pseudo-obstruction 7.1
Adrenal hemorrhage 7.1
Toxoplasma encephalitis 7.0
Carcinoma ex pleomorphic adenoma 7.0
Neuroborreliosis 7.0
Endogenous endophthalmitis 6.9
radiculoneuritis 6.9
encephalomalacia 6.9
Staphylococcus aureus endocarditis 6.9
Tension pneumocephalus 6.9
Hypophysitis 6.8
GBS 6.8
subacute endocarditis 6.8
West Nile encephalitis 6.8
Cranial nerve palsies 6.7
Acute encephalopathy 6.6
leptomeningeal metastases 6.6
Staphylococcus aureus septicemia 6.5
otitis 6.5
Tuberculomas 6.5
ear infection 6.5
Congo hemorrhagic fever 6.5
Klebsiella infection 6.5
functioning pituitary adenoma 6.4
congenital immunodeficiency 6.4
Acquired von Willebrand syndrome 6.4
abulia 6.3
penicillin allergy 6.3
Salmonella bacteremia 6.3
empyema 6.3
Ependymoma 6.3
6th nerve palsy 6.3
streptococcal pharyngitis 6.3
arachnoiditis 6.3
encephalitis 6.3
meningoencephalomyelitis 6.2
strongyloidiasis 6.2
Herpes simplex encephalitis 6.2
Sonne 6.2
bacteremia 6.2
malignant otitis externa 6.2
AIDS dementia complex 6.1
Acute infection 6.1
sensorineural hearing loss 6.1
hydrocephalus 6.1
dental abscess 6.1
congenital deafness 6.0
Spinal epidural abscess 6.0
Neurosarcoidosis 6.0
raised intracranial pressure 6.0
more...
Symptom
Brudzinski's sign 11.8
Bulging fontanelle 11.4
Nuchal rigidity 10.9
Kernig's sign 10.5
neck stiffness 9.6
meningism 9.4
sinus congestion 7.6
consciousness disturbance 7.4
rhinorrhea 6.5
Acute urinary retention 6.0
Signs and Symptoms 5.8
generalized rash 5.8
photophobia 5.6
Neurologic symptoms 5.4
prostration 5.4
impaired motor coordination 5.4
abnormal breathing 5.2
fever of unknown origin 5.1
otalgia 5.0
athetosis 4.9
hyperesthesia 4.9
visual hallucination 4.8
headache 4.7
lethargy 4.6
No adverse effect 4.6
Physical findings 4.6
seizures 4.4
neurological disability 4.1
neck pain 4.0
hemiplegia 4.0
vomiting 4.0
tachypnea 4.0
ataxic gait 3.8
paraparesis 3.8
sore throat 3.8
decreased appetite 3.8
Fluctuation 3.7
rales 3.6
ENT 3.6
ophthalmoplegia 3.6
limb pain 3.6
leg pain 3.5
torticollis 3.3
muscle cramps 3.1
dysesthesia 3.1
nausea 3.0
sleepiness 2.9
myoclonus 2.9
dizziness 2.9
flank pain 2.8
catatonia 2.8
abnormal gait 2.8
stridor 2.8
facial pain 2.8
diarrhea 2.7
dental pain 2.7
back pain 2.7
tingling 2.6
tonic-clonic seizure 2.6
ataxia 2.6
nasal discharge 2.5
chills 2.5
paresis 2.4
hypotonia 2.4
anosmia 2.4
sciatica 2.3
myalgia 2.3
hypocapnia 2.2
abdominal discomfort 2.2
numbness 2.2
hypothermia 2.2
neuralgia 2.2
incoordination 2.2
respiratory distress 2.1
vertigo 2.1
hip pain 2.1
memory loss 2.1
cyanosis 2.1
sneezing 2.0
agitation 2.0
twitching 1.9
apathy 1.9
blurred vision 1.9
spasticity 1.9
cough 1.9
tense 1.9
Ill 1.8
bradykinesia 1.7
nausea and vomiting 1.7
dysuria 1.7
paresthesia 1.7
low back pain 1.7
weakness 1.5
cachexia 1.5
hoarseness 1.4
polyuria 1.4
splenomegaly 1.3
anesthesia 1.1
cerebellar ataxia 1.1
spasm 1.1
dysarthria 1.1
dyspnea 1.0
analgesia 1.0
wheezing 0.7
constipation 0.6
abdominal pain 0.6
shortness of breath 0.6
hepatomegaly 0.4
hemoptysis 0.4
erythema 0.3
anorexia 0.2
arthralgia 0.1
hypercapnia -0.0
regurgitation -0.1
dystonia -0.1
chest pain -0.1
syncope -0.2
distraction -0.2
collapse -0.3
pain -0.4
discomfort -0.5
thinning -0.5
discomfort -0.6
fatigue -0.7
tremor -1.2
Drug
Thalomid 9.8
Amikin 9.4
Amikacin sulfate 8.7
PAPM/BP 8.6
MEPM 8.6
Iron dextran 8.5
Phenoxymethylpenicillin 8.3
CTRX 8.2
Dexamethasone sodium phosphate 8.2
CDZM 7.9
Meropenem 7.9
Garamycin 7.8
Meropenem 7.8
Rocephin 7.8
CZON 7.7
Claforan 7.3
Pantopaque 7.2
Nafcillin 7.0
Temocillin 6.9
Florfenicol 6.8
CSF 6.7
ampicillin 6.7
Ceftazidime 6.6
7-Nitroindazole 6.5
MINO 6.5
Zovirax 6.4
Zinat 6.0
Mezlocillin 5.9
Adenosine deaminase 5.8
CFS 5.6
Daclizumab 5.4
Pefloxacin 5.3
Bactrim 5.3
Augmentin 4.9
Augmentin 4.8
Amoxicillin 4.7
CPZ 4.6
AC2 4.5
CDX 4.5
Acyclovir 4.5
Trimethoprim-sulfamethoxazole 4.4
SBT 4.3
Doyle 4.3
Ofloxacin 4.3
Aminoguanidine 4.2
LCM 4.2
NBT 4.2
LCM 4.2
Hyaluronidase 4.1
OMP 4.1
CVA 4.1
Hyaluronidase 4.0
Adalimumab 3.9
Dakar 3.9
AMC 3.7
Glide 3.6
CCL 3.6
EPI 3.5
IPM 3.4
VCR 3.3
Alliance 3.1
DEX 3.1
Itraconazole 3.0
ENT 2.9
Doxycycline 2.9
ROC 2.8
RFP 2.7
pyridoxal phosphate 2.6
Fluconazole 2.6
Lovastatin 2.6
Gleevec 2.5
Prednisolone 2.4
IFN-beta 2.4
Simvastatin 2.3
CPR 2.2
Activin 2.2
Kenyan 2.2
Bevacizumab 2.2
Check 2.0
Propofol 1.9
NAG 1.9
Glycerol 1.8
Albumin 1.7
Fraction 1.6
Nitric Oxide 1.6
IFN-gamma 1.6
G-CSF 1.6
Alanine 1.5
AZT 1.4
ascorbate 1.0
IL-2 0.9
Portal 0.9
CTX 0.6
Histamine 0.5
CTX 0.5
CTX 0.5
CAM 0.4
Indomethacin 0.3
Spectrum 0.0
THF -0.0
DNase I -0.1
ABC -0.2
nitroglycerin -0.2
Asn -0.6
Gel -0.9
MAP -1.0
lactose -1.1
vitamin E -1.2
ROS -1.3
lysine -1.3
Leaf -1.5
NADH -1.5
Asthma -1.7
Monit -2.2
Dermatol -3.5
Cardiovasc -4.7
Enzyme
IgA1 protease 7.9
carboxypeptidase II 7.7
acyloxyacyl hydrolase 7.6
NAAT 7.5
acetyl-CoA hydrolase 7.1
IgA protease 7.0
lactic acid dehydrogenase 6.4
lactic acid dehydrogenase 6.4
penicillin binding protein 6.2
stromelysin-3 5.9
lactic acid dehydrogenase 5.7
lambda exonuclease 5.3
endo-N 5.1
beta-lactamase 4.8
LuxS 4.7
LTA4 hydrolase 4.7
murein hydrolase 4.7
ADH 4.6
matrix metalloproteinase 9 4.4
TACE 4.3
4-epimerase 4.2
adenosine deaminase 4.1
adenosine deaminase 4.1
indoleamine 2,3-dioxygenase 4.1
MIP 3.9
MMP-3 3.8
GTP cyclohydrolase I 3.6
transpeptidase 3.4
alpha-mannosidase 3.4
sialyltransferase 3.4
sialyltransferase 3.4
sialyltransferase 3.4
phosphoglucose isomerase 3.2
nitrite reductase 3.1
nitrite reductase 3.1
nitrite reductase 3.1
GAS 3.0
lysin 2.9
MMP 2.9
xanthine dehydrogenase 2.7
enolase 2.7
caspase-1 2.6
ceruloplasmin 2.6
alcohol dehydrogenase 2.6
lysozyme 2.5
lactate dehydrogenase 2.4
dipeptidyl peptidase IV 2.2
glutamine synthetase 2.2
aldolase 2.2
AOR 2.2
cytochrome oxidase 2.2
hexosaminidase 2.2
elastase 2.1
PAM 2.1
adenylate kinase 2.0
collagenase 1.8
matrix metalloproteinase 2 1.8
NOS 1.7
caspase-3 1.6
beta-glucuronidase 1.6
BMT 1.6
sialidase 1.5
asparaginase 1.5
myosin light chain kinase 1.5
PARP 1.5
xanthine oxidase 1.5
AST 1.4
creatine kinase 1.3
NO synthase 1.3
granzyme B 1.3
superoxide dismutase 1.2
neuraminidase 1.1
endonuclease 1.1
heme oxygenase 0.9
glutamate dehydrogenase 0.9
glutamate dehydrogenase 0.8
thromboplastin 0.8
glutamate dehydrogenase 0.8
alanine aminotransferase 0.8
hyaluronidase 0.8
CD10 0.7
catalase 0.6
CPR 0.6
aspartate aminotransferase 0.5
ATPase 0.5
phosphoinositide 3-kinase 0.4
hyaluronidase 0.3
CYP3A4 0.3
aldehyde dehydrogenase 0.3
GSK 0.2
caspase-8 0.2
peroxidase 0.1
glutathione peroxidase 0.1
MAP 0.1
carbonic anhydrase 0.1
DNase 0.0
reverse transcriptase -0.0
APC -0.1
succinate dehydrogenase -0.1
pepsin -0.1
mitogen-activated protein kinase -0.1
complex I -0.2
plasmin -0.2
gamma-glutamyl transpeptidase -0.2
transcriptase -0.3
alkaline phosphatase -0.3
proteasome -0.3
NADPH oxidase -0.4
urokinase-type plasminogen activator -0.4
phosphatidylinositol 3-kinase -0.5
NADPH oxidase -0.5
acid phosphatase -0.7
P-glycoprotein -0.8
focal adhesion kinase -0.9
protein kinase C -1.1
DNA polymerase -1.1
MEK -1.2
ACE -1.2
phospholipase C -1.2
phosphodiesterase -1.3
glutathione S-transferase -1.5
ERK -2.0
RNA polymerase -2.1
renin -2.2
luciferase -2.3
ACS -2.3
trypsin -2.4
Compound
T 39 9.9
Chloramphenicol succinate 9.8
Cefotaxime sodium 8.9
4 PA 8.8
Cefotaxime 8.3
Ceftriaxone 8.2
Moxalactam 7.7
Cefuroxime 7.3
Cefoperazone 7.2
Mezlocillin 7.1
Nafcillin 7.0
Ceftizoxime 7.0
Flucloxacillin 7.0
C6H12O6 6.9
Cefpodoxime 6.8
Ceftazidime 6.6
Cefmetazole 6.6
Cefadroxil 6.6
Methacrylic acid 6.6
Cephalothin 6.4
Penicillin 6.2
DAHP 6.1
Palmitoylethanolamide 6.1
Dexamethasone 6.1
SP 1 6.1
Geigy 6.1
Juglone 6.1
Tazobactam 6.0
Fosfomycin 6.0
Penicillin 6.0
M 3 5.8
C 10 5.8
C 10 5.8
BRL 5.8
Rifampicin 5.7
Trovafloxacin 5.7
4-pentenoic acid 5.7
Daptomycin 5.7
MBC 5.6
Cefamandole 5.6
COA 5.6
Rifabutin 5.6
Cefpirome 5.6
MBC 5.6
Cefepime 5.5
Vancomycin 5.5
SHA 5.4
Cefixime 5.4
Sulbactam 5.3
Netilmicin 5.3
NDMA 5.1
Amikacin 5.0
neopterin 4.9
Mannitol 4.9
S 1 4.9
Linezolid 4.9
Sudan I 4.9
Amoxicillin 4.8
Mannitol 4.8
Polymyxin B 4.7
Belt 4.7
Betamethasone 4.6
T 1 4.5
Cefazolin 4.5
Wellcome 4.5
Xanthine 4.5
VPM 4.4
CPZ 4.4
DBM 4.4
Aztreonam 4.4
DBM 4.4
Desmopressin 4.4
TBE 4.3
Sumatriptan 4.3
Lactate 4.3
LCR 4.3
TACE 4.3
Pentoxifylline 4.3
Cefoxitin 4.2
Lorazepam 4.2
Selectin 4.1
DTP 4.1
Imipenem 4.1
3-aminobenzamide 4.1
NBT 4.1
GPT 4.0
Baicalin 4.0
OMP 4.0
Benin 4.0
Acyclovir 3.9
Alum 3.9
Sulfamethoxazole 3.9
Lactic acid 3.9
TEC 3.9
B17 3.9
CAM 3.9
Tobramycin 3.8
Ondansetron 3.8
MIC 3.8
Factor H 3.7
UDP-GlcNAc 3.7
Probenecid 3.7
Cytochalasin D 3.7
Etanercept 3.7
FTA 3.7
D-glucuronic acid 3.7
CMP 3.6
ACNU 3.6
DPT 3.6
Gb3 3.6
PEA 3.6
Clarithromycin 3.6
Acrolein 3.5
CMP 3.5
Ofloxacin 3.5
Clindamycin 3.5
UDP-galactose 3.4
Apigenin 3.4
DEA 3.3
DEA 3.3
Guo 3.3
Ara-C 3.3
heptose 3.3
heptose 3.3
heptose 3.3
Neo 3.3
DEA 3.3
malonic acid 3.2
PAM 3.2
ITC 3.2
Neuronal 3.2
Tumor Necrosis Factor 3.2
Neu5Ac 3.2
Evans Blue 3.1
Ivermectin 3.1
Gentamicin 3.0
FDP 3.0
DTPA 3.0
phosphocreatine 3.0
DMN 3.0
Collagenase 3.0
Ara-C 2.9
Phenylalanine 2.9
Doxycycline 2.9
Emodin 2.9
Coronal 2.8
Taurine 2.8
ASC 2.8
PEP 2.8
Guo 2.7
Nitrite 2.7
alcohol dehydrogenase 2.7
Parenteral 2.7
Amphotericin B 2.6
TNF 2.6
DIC 2.6
TBP 2.5
Argentine 2.5
Uric acid 2.5
Chlorpromazine 2.5
more...