Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0085437 (bacterial meningitis)
 4,038 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Prenatal diagnosis of the Currarino triad by means of obstetrical ultrasonography is described. Three related cases are presented. A literature review regarding the therapeutic, ultrasound-guided approach are discussed. The Currarino triad is a genetically transmitted syndrome consisting of an anorectal malformation, a sacral boney defect and a presacral mass. Prenatal diagnosis aids the early recognition and surgical management of persistent spinal-rectal fistulas, thus potentially avoiding life-threatening bacterial meningitis. Copyright 1997 Elsevier Science Ireland Ltd.
 ...
PMID:Prenatal diagnosis of a Currarino triad. 979 54

Currarino triad is a rarely hereditary condition including: (1) an anorectal malformation, (2) an anterior sacral defect, and (3) a presacral mass. Autosomal dominant transmission is suggested. We reported one case of Currarino triad, who was a 3-month-old male with sacral dysgenesis, imperforated anus and enteric cyst. This case presented with acute lower limbs paralysis due to bacterial meningitis complicated with acute arachnoiditis. The diagnosis of this condition led to a work-up of his sibling, who was found to have an incomplete type. The purpose of this case is to emphasize that a high index of suspicion for timely diagnosis and treatment of Currarino triad could prevent devastating complications.
 ...
PMID:Bacterial meningitis of an infant with Currarino triad. 1260 87

We reported a 46-year-old woman with Marfan's syndrome exhibiting an incomplete Currarino triad and recurrent bacterial meningitis which recurred three times in about six months. An anterior sacral meningocele (ASM) was noted in a lumbar MRI, and multiple bone defects in the sacrum were noted in 3D-CT. Surgical approach to prevent the recurrence of infection was limited to plasty for the meningocele, but no meningitis has been observed for two years. Radical surgery should be considered in cases with ASM who recurred bacterial meningitis.
 ...
PMID:[Case of Marfan's syndrome with anterior sacral meningocele along with recurring bacterial meningitis]. 1726 Aug 11