Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085437 (bacterial meningitis)
 4,038 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The presence of antigen of D. pneumoniae and H. influenzae was detected by counter-immunoelectrophoresis (CIE) in 113 LCR of children with central nervous system (CNS) infection (17 viral, 70 bacterial and 6 tuberculous). From 41 normal children spinal fluid was obtained and used as control. Precipitation band was not observed in normal children cases of viral and tuberculosis meningitis. In 21 cases of bacterial meningitis, D. pneumoniae and H. influenzae was isolated in six cases each. In six cases of bacterial meningitis were positive both bacteriological study and CIE. In 49 cases in which culture was negative only 13 gave positive CIE. When other strains of bacteria were isolated, no positive band was detected with CIE. This technic was regarded as useful for detecting etiologic agent in purulent meningitis.
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PMID:[Counter-immunoelectrophoresis in the diagnosis of meningoencephalitis by Diplococcus pneumoniae and Hemophilus influenzae]. 0 42

We conducted a retrospective review to specify the frequency, identify the aetiological factors of bacterial meningitis in adults (BMA) and to evaluate the therapeutic protocol used. This study was conducted on 85 (BMA) cases of hospitalised patients between January 1991 and December 1995 (5 years) on our service. The BMA represented 3% of all admissions for infectious diseases at the Foundation Jeanne Ebori in Libreville. It occurred in an endemosporadic fashion. All patients were Black Africans with an average age of 33 years (range: 16-60 years). Males predominated by a ratio of 2.4. Tha patients were seen late in the evolution of the disease, as shown by the folloxing clinical signs: neuropsychic problems (100%), 25 patients (29%) were in a profound coma, 5 (6%) had a hemiplegia, 2 (2%) an hypoacousie and 1 (1%) seizure. Aetiological factors were found in 17 cases (20%) to be in the ORL sphere (sinusitis: n = 8, ear infection: n = 4), pneumopathies (n = 4) and one case of breach dure-mere. The predominant germ was pneumocoque, isolated in 55 cases (65%), 15 cases had a LCR clear (18%). Bacteria gram negative (6%) were identified in the immunocompromised HIV. Third generation cephems had an efficiency higher than beta lactamines: 83% against 73%. The mortality was 18%; 3% of the remaining patients had neurological deafness. The seriousness of the results of this survey calls for the urgent implementation of a surveillance programme.
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PMID:[Bacterial meningitis in the adult. Study of 85 cases observed in the infectious disease unit of the Fondation Jeanne Ebori (F.J.E.), Libreville, Gabon]. 1069 Apr 60