Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0085437 (bacterial meningitis)
 4,038 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retrospective review of 71 paediatric patients admitted with bacterial meningitis to the King Fahad Hospital at Al-Baha, Saudi Arabia, during an 8-year period revealed a preponderance of males (67.6%) and young subjects with 88.7% being below 24 months of age. The commonest cerebrospinal fluid pathogens in the series were Haemophilus influenzae type B (HIB), Streptococcus pneumoniae and Group B-beta haemolytic streptococcus, which were responsible for 47.3, 34.5 and 9.1% of cases respectively. Neisseria meningitidis which is a major cause of meningitis in most other reports was uncommon in the present series, and was isolated from only two patients. All the children with Group B-beta haemolytic streptococcal meningitis were below 3 months of age while 96.2% of the children with HIB meningitis were younger than 2 years. Mortality was highest (40%) among the infants with Group B-beta haemolytic streptococcal meningitis. Six (23.1%) of the HIB isolated were resistant to ampicillin and two (7.7%) were resistant to both ampicillin and chloramphenicol. There is a need for greater emphasis on prevention through the use of available vaccines including the newly introduced conjugate vaccines against HIB which are capable of eliciting immune responses in infants as young as 2 months.
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PMID:Childhood bacterial meningitis in Al-Baha province, Saudi Arabia. 159 73

The medical records of 132 children with meningitis treated at King Fahad Hospital, Hofuf, Saudi Arabia, between June 1994 and May 1996, were reviewed with a view to defining the incidence, types of meningitis, their management and clinical outcome. Subjects were classified into three groups: bacterial, partially treated, and viral meningitis. There were 37 patients (28%) in period I (1994/95) and 95 (72%) in period II (1995/96). The higher incidence in period II was accounted for by a sharply increased incidence of viral meningitis in the latter half of the period. Of the 132 patients, 36 (27.3%) had bacterial meningitis, 45 (34.1%) had partially treated meningitis and 51 (38.6%) had viral meningitis. The most common CSF isolate was Haemophilus influenzae type B (HIB) from 24 (66.7%) of the 36 bacterial meningitis cases. About half of the cases of HIB meningitis occurred in infants under the age of 12 months.
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PMID:Childhood meningitis at King Fahad Hospital, Hofuf, Saudi Arabia. 1733 5