Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0085110 (
SCID
)
11,041
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
severe combined immunodeficiency
3176
NOD
2266
Sep
701
cytokine
626
CD4
616
lymphoid
568
CD34
542
Mol
538
thymus
458
CD8
410
HLA
288
IFN-gamma
286
adenosine deaminase
261
IL-2
252
p53
200
interferon
189
IL-6
182
IL-4
181
CD45
176
X-linked
169
collagen
165
IFN
165
TCR
163
CD38
161
IL-10
157
insulin
153
CD44
144
DNA-dependent protein kinase
141
MHC
132
caspase-3
131
CXCR4
129
CD19
129
T cell receptor
126
CD133
118
CD25
113
vascular endothelial growth factor
113
chemokine
113
Adenosine deaminase
111
TNF
109
interleukin-2
108
more...
Disease
SCID
11041
tumor
2512
NOD
2266
cancer
2122
tumor growth
849
immunodeficiency
724
leukemia
659
HIV
401
breast cancer
358
metastases
336
lymphoma
315
melanoma
265
tumorigenesis
253
prostate cancer
250
carcinoma
243
graft-versus-host disease
241
Epstein
215
depression
215
acute myeloid leukemia
205
multiple myeloma
204
diabetes
202
ADA deficiency
181
tumor progression
172
AIDS
165
adenocarcinoma
154
lung cancer
149
acute lymphoblastic leukemia
145
personality disorder
134
hepatocellular carcinoma
133
infectious diseases
133
X-linked severe combined immunodeficiency
133
lymphopenia
132
Leukemia
131
major depressive disorder
128
cytomegalovirus
125
virus infection
124
primary tumor
115
colitis
107
carcinogenesis
106
Wiskott-Aldrich syndrome
100
more...
Symptom
diarrhea
74
splenomegaly
30
pain
24
hepatosplenomegaly
20
starvation
15
seizures
15
cachexia
13
functional recovery
12
fatigue
11
anorexia
11
respiratory distress
10
exhaustion
9
ataxia
9
weakness
9
alexithymia
9
cough
8
Depressive symptoms
7
headache
6
agitation
6
collapse
6
hopelessness
6
anesthesia
5
tremor
5
spasticity
5
insomnia
4
erythema
4
lethargy
4
hypotonia
4
dyspnea
4
vomiting
4
dystonia
4
discomfort
4
pelvic pain
4
hepatomegaly
4
tachypnea
3
dizziness
3
nausea
3
stigma
3
Positive and Negative Symptoms
3
Scratch
3
more...
Drug
IFN-gamma
276
IL-2
253
Dermatol
90
CSF
78
uPA
73
Adenosine deaminase
64
Norplant
63
G-CSF
26
lysine
25
Asthma
24
CTX
19
G418
19
ROS
18
BCG vaccine
16
IFN-beta
15
Taxol
12
Spectrum
12
-deoxyadenosine
12
AZT
11
AZT
11
ROC
10
Herceptin
10
Adriamycin
10
p75
9
CPT-11
9
Rituximab
9
Cardiovasc
9
CTX
8
DM1
8
Bevacizumab
8
Bortezomib
8
Spectrum
8
CTX
8
Docetaxel
8
IL-11
7
CAM
6
ABC
6
anti-CD33
6
MDS
6
MRC
6
more...
Enzyme
adenosine deaminase
265
ERK
262
adenosine deaminase
261
focal adhesion kinase
223
mitogen-activated protein kinase
151
luciferase
119
caspase-3
106
aldehyde dehydrogenase
103
urokinase-type plasminogen activator
102
protein kinase
69
alkaline phosphatase
53
reverse transcriptase
50
thymidine kinase
46
BMT
44
beta-galactosidase
40
PARP
39
proteasome
34
APC
34
MEK
33
aldehyde dehydrogenase
33
P-glycoprotein
32
ricin
31
aldehyde dehydrogenase
31
aldehyde dehydrogenase
31
aldehyde dehydrogenase
31
caspase-9
30
RNase
27
RNase
25
protein kinase C
25
CD13
23
CD10
23
RNA polymerase
21
firefly luciferase
21
caspase-8
19
ALDH
19
prostate-specific antigen
18
peroxidase
17
thyroid peroxidase
16
NO synthase
16
granzyme B
16
more...
Compound
DNA
872
Dec
802
Clin
770
DSM
450
MDA
177
oxygen
120
glucose
117
TNF
109
tyrosine
99
phosphate
92
PEG
90
calcium
90
water
89
PEG
71
GM1
53
arginine
51
ATP
49
retinoic acid
49
DBA
45
BCG
43
DBA
39
DBA
39
MTT
39
sodium
38
methionine
38
sulfate
37
cysteine
37
lysine
37
BCR
34
His
33
serine
33
LTC4
33
acetate
33
nitrogen
31
ABL
30
nitric oxide
29
tryptophan
29
alanine
28
leucine
27
iodine
26
more...