Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0079731 (B-cell lymphoma)
 16,671 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 85-year-old woman presented with macroscopic hematuria and miction pain. Cystoscopy revealed a wide-based submucosal mass, and biopsied specimens of the mass showed a B-cell lymphoma of the MALT type. Computed tomography (CT) showed a 7.5 x 3.0 cm solitary mass lesion situated from the anterior wall to the right lateral bladder wall, and magnetic resonance imaging (MRI) showed a low intensity in T1W1, high in T2W1 without invasion. After she was admitted to our hospital, TUR of the lesion was performed. The findings were consistent with extranodal marginal zone B-cell lymphoma of the MALT type. No evidence of lymphoma was found on the CT of the pelvis, chest X-ray and Gallium scintigraphy. The patient had stages I(AE) lymphoma. The patient was treated with radiation therapy to the bladder and pelvis (40 Gy in 20 fractions) and was followed with CT every 3 months. She had no evidence of recurrance.
 ...
PMID:[Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the urinary bladder]. 1573 42

A 71-year-old woman who had been treated with methotrexate (MTX) and prednisolone for rheumatoid arthritis since 2010 presented with hematuria. Cystitis was diagnosed. Chest and abdominal CT images revealed a bladder tumor, with lung and bilateral adrenal metastases. Transurethral resection of the bladder tumor (TUR-BT) confirmed these findings in September 2014. Histological findings of the bladder included large atypical lymphoid cells indicating diffuse large B-cell lymphoma. After TUR-BT, CT imaging showed that the tumor had shrunk. Still, MTX was continued. She was diagnosed with MTX-related lymphoproliferative disorders in November 2014 and MTX was discontinued. Fluorodeoxyglucose-positron emission tomography on March 2015 showed a complete response.
 ...
PMID:Spontaneous regression of methotrexate-related diffuse large B-cell lymphoma following bladder lesion resection. 2848 54