Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0079731 (B-cell lymphoma)
 16,671 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Many systemic diseases have oral and/or pharyngeal manifestations. Mucosal lesions in the upper aerodigestive tract may be caused by granulomatous inflammations, and infectious, autoimmune and neoplastic diseases before they appear systemically or otherwise. ENT specialists can play a decisive role in identifying patients with pathological mucosal changes and transfer them to dermatology, hematology, gastroenterology or maxillofacial surgery in order to assure the best possible treatment. This article presents the case of an elderly female patient with a history of necrotising severe stomatitis that turned out to be a rare B-cell lymphoma. In the second part of the article, we present a number of common and rare diseases that may be encountered in ENT practice with an overview of clinical manifestations and current diagnostic modalities.
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PMID:[Ulcerative gingivostomatitis and peridontitis]. 1649 94

A 84 year-old woman was transferred to the ENT ward for treatment of epistaxis. An anterior rhinoscopy revealed a posterior bleeding source which was cauterised. A submucosal bulge was found in the cavity floor and biopsied. Histologic examination showed diffuse large B-cell lymphoma. Oncologic examination disclosed Ann Arbor stage 1A. The patient was treated with chemotherapy followed by involved field radiation therapy. She responded well to the therapy. Intranasal lymphoma is rare in Denmark with an incidence rate of 0,1-0,2 per 100,000 per year.
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PMID:[Intranasal non-Hodgkin lymphoma diagnosed as subsidiary finding by epistaxis]. 2224 52