Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0079731 (B-cell lymphoma)
 16,671 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 65-year old man presented with acute abdominal pain and fever. The initial diagnosis was small bowel gangrene. Pathology revealed small to large abdominal vessels obliterated by cells of intravascular B-cell-lymphoma (IVL). Visceral IVL involvement is common at autopsy but rarely reported in patients with acute abdomen. The subtype of diffuse large B-cell lymphoma is a rare and aggressive malignancy, which in typical cases is characterized by cephalic or cutaneous manifestation. Few cases showed involvement of large vessels which in combination to fibrin thrombi may lead to infarction of the organ involved. Thus IVL should be considered in cases of ischemic diseases with fever of unknown origin.
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PMID:[Intravascular lymphoma causing acute abdomen]. 1714 42

Spontaneous rupture of the spleen without a history of trauma is a rare clinical entity and represents a dramatic abdominal emergency. Most cases of spontaneous rupture occur in a diseased spleen (pathological spontaneous rupture). The authors present the case of a 20-year-old man who presented with pain in the left upper quadrant and clinical signs of haemorrhagic shock. The execution of focused assessment with sonography for trauma in the emergency room revealed the rupture of a pathological spleen with massive haemoperitoneum. The patient underwent emergency splenectomy. Histological examination of the spleen diagnosed infiltration of B cell lymphoma. Spontaneous rupture of the spleen must be considered in patients with acute abdominal pain and haemorrhagic shock. The role of focused assessment with sonography for trauma in the emergency room is discussed.
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PMID:[Spontaneous rupture of the spleen in non-hodgkin lymphoma: a case report]. 1906 99

Appendiceal lymphomas are exceedingly rare, constituting around 0.015% of all gastrointestinal lymphoma cases. Burkitt's lymphoma is the second most prevalent pathology, diagnosed in 25.9% of patients. We report a case of a 36-year-old male admitted with acute abdominal pain with 2 days of evolution, localized in the right lower quadrant associated with hyporexia, but no fever. On examination he presented abdominal tenderness on the right iliac fossa. A diagnosis of acute appendicitis was made clinically. At the post-operative follow up, 2 weeks later, he presented a low back pain of high intensity, associated with swelling of the abdomen, night sweats, daily fevers and weight loss. The histopathological exam of the appendix revealed diffuse and transmural lymphoid proliferation. Immunohistochemistry suggested high grade B-cell lymphoma indicative of Burkitt's lymphoma. This patient was staged as a IVxB lymphoma and was submitted into polychemotherapy with a complete clinical response in 8 months.
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PMID:Burkitt's lymphoma presenting as acute appendicitis: a case report. 2994 79