Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0043352 (xerostomia)
 4,250 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
FLJ20035 12.9
AMY1A 10.2
SS-A 9.6
PRH2 9.4
SS-B 9.4
Sgn1 9.3
AQP5 9.2
proline rich protein 9.0
Prolyl endopeptidase-like 9.0
TMED10 8.9
FAM167A 8.9
parotid secretory protein 8.8
SIMPL 8.8
MPC3 8.8
IL17R 8.7
ITSN2 8.7
EPSTI1 8.6
PREPL 8.6
PARP12 8.5
PRH1 8.5
basic proline-rich protein 8.5
kappa light chain variable region 8.4
TDRD7 8.3
LY6E 8.3
DGK-theta 8.3
TFCP2L1 8.2
mucin MUC5B 8.2
FOXJ2 8.1
Statherin 8.0
SSB 7.9
amylase 1 7.8
MIST1 7.8
SSA 7.8
carbonic anhydrase VI 7.8
PPM1B 7.8
lacrimal 7.8
M3 muscarinic receptor 7.7
AGRN 7.7
PARP9 7.7
SGD 7.6
CLDN10 7.6
claudin-12 7.5
TNPO3 7.5
claudin-10 7.5
PRP-3 7.4
cysteine-rich secretory protein 3 7.4
PARP14 7.3
alpha-fodrin 7.3
s-laminin 7.3
ectodysplasin A 7.3
V35 7.2
BUP 7.2
EIF2AK2 7.2
HSPG2 7.1
ERO 7.1
IFI44L 7.1
AMY1 7.1
Ro60 7.1
CGI 7.0
sex-determining region Y-box 2 6.9
RNP antigen 6.9
IFI44 6.9
PHIP 6.8
WRS 6.8
Rheumatoid factor 6.7
AMY 6.7
XAF1 6.7
N-myc downstream-regulated gene 2 6.7
EDNRA 6.6
RAPA 6.6
Ro52 6.6
LIV-1 6.6
TNIP1 6.6
high molecular weight mucin 6.5
Aquaporin 1 6.5
C30 6.5
DDX58 6.4
CLCR 6.3
rheumatoid factor 6.3
K40 6.3
more...
Disease
Sjogren's syndrome, secondary 12.9
xerostomia 12.9
Radiation-induced xerostomia 12.3
Facial lymphedema 11.9
Parotid lipomatosis 11.9
Erythematous candidiasis 11.9
Gingival ulceration 11.9
squamous cell carcinoma of the larynx, stage II 11.9
Radiation caries 11.3
xerophthalmia 11.2
salivary gland disorder 10.9
Atrophic glossitis 10.9
Parotid enlargement 10.8
keratoconjunctivitis sicca 10.6
metastatic nasopharyngeal cancer 10.5
Primary Sjogren's syndrome 10.4
Rebound hypertension 10.3
Pseudomembranous candidiasis 10.3
Drug-induced gingival hyperplasia 10.3
Stage fright 10.3
Burning mouth syndrome 10.2
sinus problem 10.1
cheilosis 10.0
Annular erythema 10.0
hairy tongue 9.9
Hypertensive episodes 9.9
sialodochitis 9.6
Black hairy tongue 9.6
sicca syndrome 9.5
Overactive bladder 9.5
acute stomatitis 9.4
acute stomatitis 9.4
Head and Neck Tumor 9.4
Cyclic thrombocytopenia 9.4
LADD 9.4
Sjogren's syndrome 9.3
Distal RTA 9.3
Root caries 9.2
sialadenitis 9.2
Acute mucositis 9.0
Mucosal disease 8.8
Herpes simplex 1 8.7
Oral Mucositis 8.6
Food hoarding 8.6
Chronic Mental Illness 8.5
involutional melancholia 8.5
glossitis 8.4
hairy leukoplakia 8.4
Submandibular gland 8.4
cheilitis 8.4
Peripheral giant cell granuloma 8.3
neck cancer 8.3
Lymphocytic infiltration 8.2
Parotid gland 8.2
other autoimmune disease 8.1
Acute hyponatremia 8.1
taste disorder 8.1
trismus 8.0
Gustatory sweating 8.0
parasympathomimetic 8.0
sea sickness 8.0
parotitis 7.8
head and neck cancer 7.8
oral candidiasis 7.8
Catastrophic Illness 7.7
Oropharyngeal dysphagia 7.7
SGD 7.6
Hyponatremic 7.6
nocturia 7.5
bruxism 7.5
Lambert-Eaton myasthenic syndrome 7.4
angiectasis 7.4
ATRA syndrome 7.4
eyelid dermatitis 7.4
hypohidrosis 7.3
Dental disease 7.3
Mikulicz 7.2
gastrointestinal reflux 7.2
sclerodactyly 7.2
ozena 7.1
more...
Symptom
Drug-induced xerostomia 12.9
Mucosal dryness 12.9
Oral discomfort 11.5
glossopyrosis 10.5
symptom or complaint 10.5
mouth pain 9.8
decreased skin turgor 9.7
cracked lips 9.7
sialectasis 9.7
upset stomach 9.6
abnormal taste 9.5
glossodynia 9.5
dry eye 9.4
inflammation of the tonsils 9.2
dry throat 9.1
excessive urination 8.9
hypnagogic hallucination 8.8
Moderate pain 8.8
feeling dizzy 8.8
stuffy nose 8.8
blurred vision 8.7
loss of taste 8.7
bloodshot eyes 8.5
Rebound insomnia 8.3
halitosis 8.2
feeling nervous 8.2
redness of the eyes 8.1
lightheadedness 8.0
Spasmodic Torticollis 8.0
sinus pain 8.0
neurological pain 8.0
constipation 7.9
Climacteric symptoms 7.9
Urge incontinence 7.8
Mouth breathing 7.8
vaginal itching 7.8
urinary frequency 7.7
Vaginal dryness 7.7
dizziness 7.7
sleepiness 7.7
finger pain 7.7
drooling 7.7
sinus congestion 7.5
musculoskeletal impairment 7.5
dysosmia 7.4
Swallowing problems 7.3
epigastric distress 7.3
thirsty 7.1
Pain symptoms 7.1
frequent urination 7.0
insomnia 7.0
GI irritation 6.9
itchy nose 6.9
brittle nails 6.8
Extrapyramidal symptoms 6.8
decreased appetite 6.8
hot flashes 6.8
eye discharge 6.8
nausea 6.8
excessive sweating 6.7
nasal congestion 6.5
physical symptom 6.5
hot flushes 6.5
breakthrough pain 6.5
Pain at rest 6.5
asthenia 6.5
orofacial pain 6.4
throat irritation 6.4
Sedation 6.3
stomach pain 6.2
Musculoskeletal symptoms 6.2
dry skin 6.1
Visceral pain 6.0
astasia 5.9
dental pain 5.8
Signs and Symptoms 5.8
lassitude 5.7
polyuria 5.7
nausea and vomiting 5.6
cancer pain 5.5
more...
Drug
Evoxac 12.9
Cevimeline 12.1
Asiasarum root 11.3
Serzone 11.1
Trospium chloride 10.6
Tolterodine Tartrate 10.5
Solifenacin succinate 10.4
Ditropan 10.3
Clemastine fumarate 10.3
Halazepam 10.3
Trospium 10.3
Ditropan 10.2
Darifenacin 10.1
Imidafenacin 9.9
Ethyol 9.9
Spiriva 9.8
Tolterodine tartrate 9.7
Angelica dahurica root 9.7
Darifenacin hydrobromide 9.5
Ludiomil 9.3
Sodium picosulfate 9.3
Ludiomil 9.3
Ebastine 9.2
Cnidii rhizoma 9.2
Amifostine 9.2
Duloxetine 9.1
Trazodon 9.1
Longgu 9.1
Pilocarpine 8.9
Lofexidine 8.9
Zyrtec 8.9
Tazorac 8.9
Meridia 8.9
Nabilone 8.8
Trimipramine 8.7
Sirdalud 8.7
Frovatriptan 8.7
Gastrin I 8.6
Alarin 8.6
Dantrium 8.5
Reboxetine 8.5
Zotepine 8.5
Frova 8.5
Scutellaria root 8.5
Periactin 8.4
Eszopiclone 8.4
Carafate 8.3
Periactin 8.3
Estulic 8.3
Loratadine 8.3
Iloperidone 8.3
Zomig 8.2
Fluspirilene 8.2
Navoban 8.2
Navoban 8.2
Catapres 8.2
Acrivastine 8.2
Tora 8.1
Escitalopram 8.1
Zyban 8.1
Adinazolam 8.1
Brofaromine 8.1
ULR 8.1
Myobloc 8.0
Domperidone 8.0
Indoramin 8.0
Belladonna 7.8
Diethylpropion 7.8
Escitalopram oxalate 7.8
MCZ 7.8
Lisdexamfetamine dimesylate 7.7
Tolvaptan 7.7
Ipecac 7.7
Foradil 7.6
Foradil 7.6
Methyldopa 7.6
Conivaptan 7.5
Foradil 7.5
Hoelen 7.5
Dexfenfluramine 7.5
more...
Enzyme
MSAS 8.6
prostate-specific membrane antigen 5.4
nucleotide pyrophosphatase 4.3
TSP-1 4.1
botulinum neurotoxin 4.0
cathepsin S 3.9
monoamine oxidase 3.8
alpha-amylase 3.7
BMT 3.5
SPS 3.2
prostate-specific antigen 3.1
CYP3A4 3.0
lysozyme 2.9
bromelain 2.9
uricase 2.6
CPS 2.6
ACE 2.4
indoleamine 2,3-dioxygenase 2.4
histidine decarboxylase 2.4
paraoxonase 2.1
paraoxonase 1.8
cholinesterase 1.8
MIP 1.6
carbonic anhydrase 1.6
tryptase 1.4
acetylcholinesterase 1.4
kallikrein 1.3
elastase 1.3
lipase 1.3
caspase-1 1.3
choline acetyltransferase 1.2
sulfatase 1.2
ribonuclease 1.2
ribonuclease 1.2
HSD 1.1
renin 1.1
urease 1.0
NOS 1.0
urease 1.0
PCP 1.0
alanine aminotransferase 1.0
glutamate dehydrogenase 0.8
glutamate dehydrogenase 0.8
glutamate dehydrogenase 0.8
transglutaminase 0.6
hexokinase 0.5
glucose oxidase 0.5
aspartate aminotransferase 0.5
peroxidase 0.5
phosphoinositide 3-kinase 0.4
AST 0.3
collagenase 0.3
AMPK 0.3
reverse transcriptase 0.2
alkaline phosphatase 0.1
phospholipase A2 0.1
caspase-3 0.1
beta-galactosidase 0.0
MAP 0.0
beta-glucuronidase -0.0
RNase -0.1
pepsin -0.2
RNase -0.3
plasmin -0.3
MEK -0.3
phosphodiesterase -0.3
creatine kinase -0.3
transcriptase -0.3
CD10 -0.4
trypsin -0.5
focal adhesion kinase -0.6
superoxide dismutase -0.7
AMPK -0.7
AMP-activated protein kinase -0.8
thromboplastin -0.8
PARP -0.9
proteasome -0.9
protein kinase -1.1
APC -1.1
calcineurin -1.2
more...
Compound
ethyl 2,2-diphenylpropanoate 11.9
L-Hyoscyamine 11.3
Banthine 10.9
Pilocarpine hydrochloride 10.9
Tolterodine 10.6
Oxybutynin 10.5
1-phenyl-1,2,3,4-tetrahydroisoquinoline 10.5
1-phenyl-1,2,3,4-tetrahydroisoquinoline 10.5
Dothiepin 9.7
Bupropion hydrochloride 9.6
Soriatane 9.5
Sodium picosulfate 9.5
Propiverine 9.5
Bromoacetylcholine 9.4
Doxepin hydrochloride 9.2
Propantheline 9.0
Isocarboxazide 9.0
Tizanidine 8.9
Rilmenidine 8.9
Moxonidine 8.9
Nefazodone 8.8
Fluorometholone 8.8
Fastin 8.8
Pilocarpine 8.8
Amifostine 8.7
Glycopyrrolate 8.6
Sibutramine 8.6
Guanfacine 8.6
Guanabenz 8.6
Diethylpropion 8.4
Fenistil 8.2
Venlafaxine 8.2
C10H16 8.2
T undecanoate 8.1
Dimenhydrinate 8.0
Thiothixene 8.0
Zyban 8.0
Cyclobenzaprine 8.0
Bupropion 8.0
Benztropine 7.9
quinuclidine 7.9
quinuclidine 7.9
WR-1065 7.8
Doxepin 7.8
Protriptyline 7.7
NMHE 7.7
Lentizol 7.7
Mirtazapine 7.6
Dexpanthenol 7.5
Quetiapine 7.4
Meclizine 7.3
Prochlorperazine 7.3
Cetylpyridinium chloride 7.2
1-methyl-1H-imidazole 7.2
Loxapine 7.1
Phenergan 7.1
Fluvoxamine 7.0
Geigy 7.0
Terfenadine 6.9
Pirenzepine 6.9
Olanzapine 6.9
Amantadine 6.9
Phentermine 6.8
Sertindole 6.8
Sertraline 6.8
Anethole 6.7
Cetylpyridinium chloride 6.5
Azelastine 6.5
Trazodone 6.5
C6H12 6.5
Ectoine 6.4
13-cis-Retinoic acid 6.4
Fenfluramine 6.4
Cepharanthine 6.4
Citalopram 6.3
Emetine 6.3
Esmolol 6.3
Brimonidine 6.3
Tramadol 6.3
Phenelzine 6.2
more...