Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0043352 (xerostomia)
 4,250 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FLJ20035 12.9
AMY1A 10.2
SS-A 9.6
PRH2 9.4
SS-B 9.4
Sgn1 9.3
AQP5 9.2
proline rich protein 9.0
Prolyl endopeptidase-like 9.0
TMED10 8.9
FAM167A 8.9
parotid secretory protein 8.8
SIMPL 8.8
MPC3 8.8
ITSN2 8.7
IL17R 8.7
PREPL 8.6
EPSTI1 8.6
PARP12 8.5
basic proline-rich protein 8.5
PRH1 8.5
kappa light chain variable region 8.4
TDRD7 8.3
LY6E 8.3
DGK-theta 8.3
TFCP2L1 8.2
mucin MUC5B 8.2
FOXJ2 8.1
Statherin 8.0
SSB 7.9
MIST1 7.8
amylase 1 7.8
SSA 7.8
carbonic anhydrase VI 7.8
PPM1B 7.8
lacrimal 7.8
M3 muscarinic receptor 7.7
AGRN 7.7
PARP9 7.7
SGD 7.6
CLDN10 7.6
claudin-12 7.5
TNPO3 7.5
claudin-10 7.5
cysteine-rich secretory protein 3 7.4
PRP-3 7.4
PARP14 7.3
alpha-fodrin 7.3
s-laminin 7.3
ectodysplasin A 7.3
V35 7.2
BUP 7.2
EIF2AK2 7.2
HSPG2 7.1
ERO 7.1
IFI44L 7.1
AMY1 7.1
Ro60 7.1
CGI 7.0
sex-determining region Y-box 2 6.9
IFI44 6.9
RNP antigen 6.9
PHIP 6.8
WRS 6.8
Rheumatoid factor 6.7
AMY 6.7
N-myc downstream-regulated gene 2 6.7
XAF1 6.7
EDNRA 6.6
RAPA 6.6
Ro52 6.6
TNIP1 6.6
LIV-1 6.6
high molecular weight mucin 6.5
Aquaporin 1 6.5
C30 6.5
DDX58 6.4
CLCR 6.3
rheumatoid factor 6.3
K40 6.3
ALX 6.3
PTF1 6.3
prostate-specific membrane antigen 6.2
OBS 6.2
KRP 6.2
lactoperoxidase (LPO) 6.2
muscarinic receptor 6.1
muscarinic M2 receptor 6.1
P140 6.1
RDC 6.1
SLC3A1 6.1
Follistatin-like 1 6.1
MUC5B 6.0
IL12A 6.0
SMG 6.0
DDX6 5.9
TAC1 5.9
HMT 5.9
WBS 5.9
PTTG1 5.9
histamine H1 receptor 5.9
BLK 5.8
OX2R 5.8
CD79B 5.8
GBP1 5.8
PON3 5.8
FAN 5.8
IRF5 5.8
muscarinic acetylcholine receptor 5.8
EDAR 5.7
X-1 5.7
TRIM21 5.7
EDN1 5.6
FPR2 5.6
TNG 5.6
ANO1 5.6
beta 3-adrenergic receptor 5.6
NPP1 5.6
beta-3 5.6
toll-like receptor 3 5.5
FGF10 5.5
ANA 5.5
TPX 5.5
SWS 5.5
TRPM2 5.4
Fibroblast growth factor receptor 2 5.4
GDI 5.4
FACT 5.4
LVM 5.4
PON2 5.4
KIN 5.4
Calnexin 5.4
Acetylcholine receptor 5.3
HSG 5.3
claudin-3 5.3
FCGR2A 5.3
aquaporin-3 5.3
STIM2 5.3
MG1 5.3
SATB1 5.3
noradrenaline transporter 5.3
sodium-potassium ATPase 5.3
junctional adhesion molecule 5.2
NPC 5.2
Neutral endopeptidase 5.2
EAT 5.2
NOV 5.2
CD49a 5.1
PRDM1 5.1
PKH 5.1
CRT 5.1
MMP-8 5.1
RhoG 5.1
CMAP 5.0
BID 5.0
cytochrome P450 2D6 5.0
TCF3 5.0
NNT 5.0
TRPV3 5.0
water channel 4.9
more...
Disease
xerostomia 12.9
Sjogren's syndrome, secondary 12.9
Radiation-induced xerostomia 12.3
Gingival ulceration 11.9
squamous cell carcinoma of the larynx, stage II 11.9
Facial lymphedema 11.9
Parotid lipomatosis 11.9
Erythematous candidiasis 11.9
Radiation caries 11.3
xerophthalmia 11.2
salivary gland disorder 10.9
Atrophic glossitis 10.9
Parotid enlargement 10.8
keratoconjunctivitis sicca 10.6
metastatic nasopharyngeal cancer 10.5
Primary Sjogren's syndrome 10.4
Drug-induced gingival hyperplasia 10.3
Pseudomembranous candidiasis 10.3
Rebound hypertension 10.3
Stage fright 10.3
Burning mouth syndrome 10.2
sinus problem 10.1
cheilosis 10.0
Annular erythema 10.0
hairy tongue 9.9
Hypertensive episodes 9.9
sialodochitis 9.6
Black hairy tongue 9.6
sicca syndrome 9.5
Overactive bladder 9.5
Head and Neck Tumor 9.4
acute stomatitis 9.4
acute stomatitis 9.4
Cyclic thrombocytopenia 9.4
LADD 9.4
Sjogren's syndrome 9.3
Distal RTA 9.3
Root caries 9.2
sialadenitis 9.2
Acute mucositis 9.0
Mucosal disease 8.8
Herpes simplex 1 8.7
Oral Mucositis 8.6
Food hoarding 8.6
involutional melancholia 8.5
Chronic Mental Illness 8.5
glossitis 8.4
hairy leukoplakia 8.4
Submandibular gland 8.4
cheilitis 8.4
Peripheral giant cell granuloma 8.3
neck cancer 8.3
Lymphocytic infiltration 8.2
Parotid gland 8.2
other autoimmune disease 8.1
taste disorder 8.1
Acute hyponatremia 8.1
trismus 8.0
Gustatory sweating 8.0
parasympathomimetic 8.0
sea sickness 8.0
parotitis 7.8
head and neck cancer 7.8
oral candidiasis 7.8
Catastrophic Illness 7.7
Oropharyngeal dysphagia 7.7
SGD 7.6
Hyponatremic 7.6
nocturia 7.5
bruxism 7.5
Lambert-Eaton myasthenic syndrome 7.4
eyelid dermatitis 7.4
angiectasis 7.4
ATRA syndrome 7.4
hypohidrosis 7.3
Dental disease 7.3
Mikulicz 7.2
gastrointestinal reflux 7.2
sclerodactyly 7.2
ozena 7.1
tooth wear 7.1
polyarthralgia 7.1
Oropharyngeal candidiasis 7.1
Necrotizing vasculitis 7.1
psychoactive substance abuse 7.1
ranula 7.1
Hypokalemic periodic paralysis 7.1
hysterical neurosis 7.1
hypergammaglobulinemia 7.1
Pulmonary sarcoidosis 7.0
dental abscess 7.0
Temporomandibular Disorders 6.9
Emphysematous gastritis 6.9
Splenic artery aneurysm 6.9
Oral lichen planus 6.8
dental caries 6.8
Oral submucous fibrosis 6.8
tooth loss 6.8
dacryoadenitis 6.8
Severe depression 6.8
chronic pharyngitis 6.8
Bladder outlet obstruction 6.7
geographic tongue 6.7
HAM 6.7
Pure autonomic failure 6.7
oropharyngeal cancer 6.6
Distal renal tubular acidosis 6.6
unknown primary cancer 6.6
Akathisia 6.6
lymphogranuloma 6.6
renal tubular acidosis 6.6
dysautonomia 6.6
dysphagia 6.6
perennial rhinitis 6.6
nasopharyngitis 6.5
Sclerosing cholangitis 6.5
Raynaud's phenomenon 6.5
xerosis 6.5
Sheehan's syndrome 6.5
hypotension and shock 6.4
metastatic pheochromocytoma 6.4
polyarticular arthritis 6.4
gingivitis 6.4
SWS 6.4
Tubulointerstitial nephritis 6.4
myofasciitis 6.3
Hyperamylasemia 6.3
Opioid use disorder 6.3
Jaccoud 6.3
polyclonal hypergammaglobulinemia 6.3
Alveolar bone loss 6.3
impaired social functioning 6.3
Microangiopathy 6.2
periodontal disease 6.2
anhidrosis 6.2
Myofascial pain 6.2
Amebic liver abscess 6.2
Social Anxiety 6.1
Oral ulcers 6.1
Malignant disease 6.1
incontinence 6.1
aphthous stomatitis 6.1
Advanced cancer 6.1
RDC 6.1
candidiasis 6.1
KCS 6.1
pharyngeal cancer 6.1
Sexual dysfunction 6.1
chronic laryngitis 6.1
leukoplakia 6.1
retinal vascular occlusion 6.1
autoimmune disease 6.0
bipolar depression 6.0
dry socket 6.0
connective tissue disease 6.0
Nasopharyngeal carcinoma 6.0
uricosuria 6.0
Bronchiolitis obliterans organizing pneumonia 6.0
Chronic GVHD 6.0
cycloplegia 6.0
more...
Symptom
Mucosal dryness 12.9
Drug-induced xerostomia 12.9
Oral discomfort 11.5
glossopyrosis 10.5
symptom or complaint 10.5
mouth pain 9.8
decreased skin turgor 9.7
cracked lips 9.7
sialectasis 9.7
upset stomach 9.6
abnormal taste 9.5
glossodynia 9.5
dry eye 9.4
inflammation of the tonsils 9.2
dry throat 9.1
excessive urination 8.9
feeling dizzy 8.8
Moderate pain 8.8
hypnagogic hallucination 8.8
stuffy nose 8.8
blurred vision 8.7
loss of taste 8.7
bloodshot eyes 8.5
Rebound insomnia 8.3
halitosis 8.2
feeling nervous 8.2
redness of the eyes 8.1
lightheadedness 8.0
Spasmodic Torticollis 8.0
neurological pain 8.0
sinus pain 8.0
constipation 7.9
Climacteric symptoms 7.9
Mouth breathing 7.8
Urge incontinence 7.8
vaginal itching 7.8
urinary frequency 7.7
Vaginal dryness 7.7
dizziness 7.7
sleepiness 7.7
finger pain 7.7
drooling 7.7
sinus congestion 7.5
musculoskeletal impairment 7.5
dysosmia 7.4
Swallowing problems 7.3
epigastric distress 7.3
thirsty 7.1
Pain symptoms 7.1
frequent urination 7.0
insomnia 7.0
itchy nose 6.9
GI irritation 6.9
Extrapyramidal symptoms 6.8
brittle nails 6.8
decreased appetite 6.8
hot flashes 6.8
eye discharge 6.8
nausea 6.8
excessive sweating 6.7
nasal congestion 6.5
physical symptom 6.5
hot flushes 6.5
breakthrough pain 6.5
Pain at rest 6.5
asthenia 6.5
orofacial pain 6.4
throat irritation 6.4
Sedation 6.3
stomach pain 6.2
Musculoskeletal symptoms 6.2
dry skin 6.1
Visceral pain 6.0
astasia 5.9
dental pain 5.8
Signs and Symptoms 5.8
lassitude 5.7
polyuria 5.7
nausea and vomiting 5.6
cancer pain 5.5
polydipsia 5.5
precordial pain 5.4
bitter taste 5.4
abdominal cramps 5.4
blushing 5.4
hangover 5.4
sore throat 5.3
dysesthesia 5.3
eye pain 5.3
rectal pain 5.3
mastalgia 5.3
hoarseness 5.3
Chronic pelvic pain 5.2
night sweats 5.2
arthralgia 5.2
fatigue 5.2
sneezing 5.1
microbial colonization 5.1
tingling 5.1
heartburn 5.0
paresthesia 5.0
Multimorbidity 5.0
vomiting 5.0
agitation 5.0
abdominal discomfort 4.9
anorexia 4.9
headache 4.9
chronic back pain 4.9
rhinorrhea 4.9
periorbital edema 4.9
discomfort 4.9
discomfort 4.9
facial pain 4.8
auditory hallucination 4.8
swollen joints 4.8
dysuria 4.8
non-productive cough 4.7
dark urine 4.7
adenitis 4.7
exertional dyspnea 4.7
myalgia 4.7
snoring 4.7
visual hallucination 4.7
tremor 4.7
muscle cramps 4.6
Burning 4.6
neck stiffness 4.6
persistent cough 4.6
shortness of breath 4.6
rales 4.5
numbness 4.5
menopausal symptoms 4.5
bloating 4.5
forgetfulness 4.5
joint stiffness 4.4
erythema 4.4
vertigo 4.4
spasticity 4.4
hyperacusis 4.4
Poor sleep 4.4
clonus 4.3
prostration 4.3
dysarthria 4.3
chest tightness 4.3
bladder pain 4.3
abdominal fullness 4.2
dyspnea 4.2
belching 4.2
hypertonia 4.2
weakness 4.2
skin irritation 4.1
neuralgia 4.1
lethargy 4.1
dystonia 4.1
nasal discharge 4.0
orthopnea 4.0
blackout 4.0
cough 4.0
motor symptom 4.0
ophthalmoplegia 4.0
more...
Drug
Evoxac 12.9
Cevimeline 12.1
Asiasarum root 11.3
Serzone 11.1
Trospium chloride 10.6
Tolterodine Tartrate 10.5
Solifenacin succinate 10.4
Trospium 10.3
Halazepam 10.3
Clemastine fumarate 10.3
Ditropan 10.3
Ditropan 10.2
Darifenacin 10.1
Imidafenacin 9.9
Ethyol 9.9
Spiriva 9.8
Tolterodine tartrate 9.7
Angelica dahurica root 9.7
Darifenacin hydrobromide 9.5
Ludiomil 9.3
Sodium picosulfate 9.3
Ludiomil 9.3
Ebastine 9.2
Cnidii rhizoma 9.2
Amifostine 9.2
Duloxetine 9.1
Trazodon 9.1
Longgu 9.1
Pilocarpine 8.9
Lofexidine 8.9
Tazorac 8.9
Meridia 8.9
Zyrtec 8.9
Nabilone 8.8
Sirdalud 8.7
Trimipramine 8.7
Frovatriptan 8.7
Gastrin I 8.6
Alarin 8.6
Dantrium 8.5
Reboxetine 8.5
Zotepine 8.5
Scutellaria root 8.5
Frova 8.5
Periactin 8.4
Eszopiclone 8.4
Carafate 8.3
Estulic 8.3
Periactin 8.3
Loratadine 8.3
Iloperidone 8.3
Zomig 8.2
Fluspirilene 8.2
Navoban 8.2
Navoban 8.2
Catapres 8.2
Acrivastine 8.2
Tora 8.1
Escitalopram 8.1
Zyban 8.1
Brofaromine 8.1
Adinazolam 8.1
ULR 8.1
Myobloc 8.0
Domperidone 8.0
Indoramin 8.0
Belladonna 7.8
Diethylpropion 7.8
MCZ 7.8
Escitalopram oxalate 7.8
Lisdexamfetamine dimesylate 7.7
Tolvaptan 7.7
Ipecac 7.7
Foradil 7.6
Foradil 7.6
Methyldopa 7.6
Foradil 7.5
Conivaptan 7.5
Hoelen 7.5
Dexfenfluramine 7.5
Atomoxetine 7.5
Demeclocycline 7.4
Mirtazapine 7.4
MCZ 7.4
Moclobemide 7.4
Lormetazepam 7.3
Lioresal 7.3
Regadenoson 7.3
Cortisporin 7.3
Sensodyne 7.3
Potassium citrate 7.2
Almotriptan 7.2
Tianma 7.1
Mazindol 7.0
Lornoxicam 7.0
Sulla 6.9
Hyoscyamine 6.9
Anafranil 6.8
Amoxapine 6.8
Ipratropium bromide 6.7
Rebamipide 6.6
Pyridostigmine bromide 6.6
Modafinil 6.6
Buscopan 6.6
Hyoscyamine 6.6
Tianeptine 6.6
Subutex 6.5
Thioridazine 6.5
Pyridostigmine bromide 6.4
Ketotifen 6.3
Orlistat 6.3
Mizoribine 6.3
Almotriptan 6.3
Tramal 6.2
Anafranil 6.2
Cinnarizine 6.1
Flupenthixol 6.0
Clonidine 6.0
Zonisamide 5.9
Tinidazole 5.8
Pregabalin 5.7
Acitretin 5.7
Beta-2 5.5
BOTOX 5.5
Tibolone 5.4
Scopolamine 5.3
Hydrochlorothiazide 5.2
Abatacept 5.2
EFV 5.2
Botox 5.2
NOV 5.1
BoNT/A 5.1
Glucantime 5.0
KGF 5.0
Indinavir 5.0
CTM 4.9
Triazolam 4.8
Sucralfate 4.8
Cetuximab 4.6
CTM 4.5
Guanidine 4.5
Isotretinoin 4.5
Cisapride 4.5
Guanidine 4.5
Prednisone 4.5
Vorinostat 4.4
Atropine 4.4
Prednisolone 4.3
Retinoic Acid 4.3
Cantor 4.3
Dextrose 4.2
Gabapentin 4.1
Orion 4.0
Clofibrate 3.7
TES 3.7
Tuberculin 3.7
Portal 3.6
Horizon 3.6
Taxotere 3.6
Budesonide 3.6
more...
Enzyme
MSAS 8.6
prostate-specific membrane antigen 5.4
nucleotide pyrophosphatase 4.3
TSP-1 4.1
botulinum neurotoxin 4.0
cathepsin S 3.9
monoamine oxidase 3.8
alpha-amylase 3.7
BMT 3.5
SPS 3.2
prostate-specific antigen 3.1
CYP3A4 3.0
lysozyme 2.9
bromelain 2.9
uricase 2.6
CPS 2.6
ACE 2.4
indoleamine 2,3-dioxygenase 2.4
histidine decarboxylase 2.4
paraoxonase 2.1
paraoxonase 1.8
cholinesterase 1.8
MIP 1.6
carbonic anhydrase 1.6
tryptase 1.4
acetylcholinesterase 1.4
kallikrein 1.3
elastase 1.3
lipase 1.3
caspase-1 1.3
choline acetyltransferase 1.2
sulfatase 1.2
ribonuclease 1.2
ribonuclease 1.2
HSD 1.1
renin 1.1
urease 1.0
NOS 1.0
urease 1.0
PCP 1.0
alanine aminotransferase 1.0
glutamate dehydrogenase 0.8
glutamate dehydrogenase 0.8
glutamate dehydrogenase 0.8
transglutaminase 0.6
hexokinase 0.5
glucose oxidase 0.5
aspartate aminotransferase 0.5
peroxidase 0.5
phosphoinositide 3-kinase 0.4
AST 0.3
collagenase 0.3
AMPK 0.3
reverse transcriptase 0.2
alkaline phosphatase 0.1
phospholipase A2 0.1
caspase-3 0.1
beta-galactosidase 0.0
MAP 0.0
beta-glucuronidase -0.0
RNase -0.1
pepsin -0.2
RNase -0.3
plasmin -0.3
MEK -0.3
phosphodiesterase -0.3
creatine kinase -0.3
transcriptase -0.3
CD10 -0.4
trypsin -0.5
focal adhesion kinase -0.6
superoxide dismutase -0.7
AMPK -0.7
AMP-activated protein kinase -0.8
thromboplastin -0.8
PARP -0.9
proteasome -0.9
protein kinase -1.1
APC -1.1
calcineurin -1.2
RNA polymerase -1.2
phospholipase C -1.3
ERK -1.3
mitogen-activated protein kinase -1.4
glutathione peroxidase -1.6
glutathione S-transferase -1.6
catalase -1.9
lactate dehydrogenase -2.0
ATPase -2.1
luciferase -2.3
ACS -2.4
protein kinase C -2.7
Compound
ethyl 2,2-diphenylpropanoate 11.9
L-Hyoscyamine 11.3
Pilocarpine hydrochloride 10.9
Banthine 10.9
Tolterodine 10.6
Oxybutynin 10.5
1-phenyl-1,2,3,4-tetrahydroisoquinoline 10.5
1-phenyl-1,2,3,4-tetrahydroisoquinoline 10.5
Dothiepin 9.7
Bupropion hydrochloride 9.6
Soriatane 9.5
Sodium picosulfate 9.5
Propiverine 9.5
Bromoacetylcholine 9.4
Doxepin hydrochloride 9.2
Propantheline 9.0
Isocarboxazide 9.0
Tizanidine 8.9
Rilmenidine 8.9
Moxonidine 8.9
Nefazodone 8.8
Fluorometholone 8.8
Fastin 8.8
Pilocarpine 8.8
Amifostine 8.7
Glycopyrrolate 8.6
Sibutramine 8.6
Guanfacine 8.6
Guanabenz 8.6
Diethylpropion 8.4
Fenistil 8.2
Venlafaxine 8.2
C10H16 8.2
T undecanoate 8.1
Dimenhydrinate 8.0
Thiothixene 8.0
Zyban 8.0
Cyclobenzaprine 8.0
Bupropion 8.0
Benztropine 7.9
quinuclidine 7.9
quinuclidine 7.9
WR-1065 7.8
Doxepin 7.8
Protriptyline 7.7
Lentizol 7.7
NMHE 7.7
Mirtazapine 7.6
Dexpanthenol 7.5
Quetiapine 7.4
Prochlorperazine 7.3
Meclizine 7.3
1-methyl-1H-imidazole 7.2
Cetylpyridinium chloride 7.2
Phenergan 7.1
Loxapine 7.1
Fluvoxamine 7.0
Geigy 7.0
Terfenadine 6.9
Pirenzepine 6.9
Olanzapine 6.9
Amantadine 6.9
Phentermine 6.8
Sertindole 6.8
Sertraline 6.8
Anethole 6.7
Cetylpyridinium chloride 6.5
Azelastine 6.5
Trazodone 6.5
C6H12 6.5
Ectoine 6.4
13-cis-Retinoic acid 6.4
Fenfluramine 6.4
Cepharanthine 6.4
Citalopram 6.3
Emetine 6.3
Esmolol 6.3
Tramadol 6.3
Brimonidine 6.3
Phenelzine 6.2
Pseudoephedrine 6.2
Fexofenadine 6.2
Phenelzine 6.1
Paricalcitol 6.1
Cetirizine 6.1
Zolmitriptan 6.0
Didanosine 6.0
Disopyramide 5.9
SHM 5.9
Amitriptyline 5.9
Botulinum toxin type A 5.8
Astemizole 5.8
Clomipramine 5.8
TTS 5.8
Chlorpheniramine 5.8
C 10 5.7
C 10 5.7
Chlorpheniramine 5.7
Ketanserin 5.6
azulene 5.6
Rose Bengal 5.5
Imipramine 5.5
Imipramine 5.5
Paroxetine 5.5
Nandrolone 5.5
Pyridostigmine 5.5
Bethanechol 5.4
Lip 5.4
Sufentanil 5.4
3,4-DAP 5.3
Physostigmine 5.3
SHB 5.2
DAMP 5.2
Xylitol 5.2
Hydrochlorothiazide 5.1
PDQ 5.1
Dexmedetomidine 5.1
Foscarnet 5.1
NDMA 5.0
4-vinylphenol 5.0
Indinavir 5.0
Allergan 4.9
Amantadine 4.9
Amantadine 4.9
1H-indazole 4.9
AMD 4.9
Oxycodone 4.9
Cyproheptadine 4.9
Nicotinic acid adenine dinucleotide phosphate 4.8
Amantadine 4.8
Desipramine 4.8
Sucralfate 4.8
3,4-Methylenedioxymethamphetamine 4.8
ANA 4.8
ANA 4.8
Chloral hydrate 4.8
Ondansetron 4.7
Miconazole 4.7
MPB 4.7
Doxazosin 4.7
Selegiline 4.7
Chlorhexidine 4.7
Mebendazole 4.7
Cordycepin 4.6
Cordycepin 4.6
Cordycepin 4.6
DHC 4.6
Tempol 4.6
Alprazolam 4.5
Cisapride 4.5
DFS 4.5
Pimozide 4.4
Flecainide 4.4
DAMP 4.4
Atropine 4.4
Prednisolone 4.4
Neostigmine 4.3
Desmopressin 4.3
K19 4.3
Labetalol 4.3
more...