Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0043346 (xeroderma pigmentosum)
 2,924 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
trichothiodystrophy 12.6
XPCC 12.6
XPV 12.5
ERCC4 protein 12.4
progestin and adipoQ receptor family member III 12.4
XPA binding protein 1 12.1
XPE 12.1
DNA repair endonuclease XPF 12.0
GTF2H5 12.0
RNASE6PL 11.8
growth arrest and DNA-damage-inducible beta 11.8
ERCC2 protein 11.8
X-ray repair cross-complementing protein 3 11.8
POLH 11.8
XPA 11.7
XPG 11.7
XPB 11.7
RAD30B 11.6
XAB2 protein 11.6
HELD 11.4
Transcription factor II H 11.4
ERCC3 11.4
excision repair cross-complementing rodent repair deficiency, complementation group 2 11.4
pygopus 2 11.4
HUEL 11.4
HSSB 11.3
XPD 11.2
XPC 11.2
transcription factor TFIIH 11.2
BTF2 11.2
DDB2 11.1
OMCG1 11.1
POLD 11.1
WDR76 11.1
CLEC2A 11.1
DNA polymerase eta 11.1
xeroderma pigmentosum variant 11.0
HR23B 11.0
transcription factor II H 10.9
excision repair cross-complementing 1 10.9
hHR23B 10.9
XPF 10.8
PARP-10 10.8
XAB2 10.8
p33ING2 10.8
RAD23 homolog B 10.8
FHOD1 10.8
cullin 4A 10.8
TFIIH 10.7
DNA damage-binding protein 2 10.7
ERCC4 10.6
ERCC5 10.6
ERCC2 10.5
PPIE 10.4
xeroderma pigmentosum, complementation group C 10.4
chromobox homolog 4 10.4
Micrococcus luteus UV endonuclease 10.4
hHR23A 10.3
RAD26 10.3
HHR23A 10.2
xeroderma pigmentosum D 10.2
cullin 4B 10.2
Bloom syndrome 10.1
NER 10.1
OTUD4 10.0
xeroderma pigmentosum complementary group D 10.0
RAD23B 9.9
DDB1 9.9
DDX11 9.8
UV20 9.7
ERCC1 9.7
PATCHED 9.6
RNF135 9.6
ERCC1 protein 9.5
hRad50 9.5
hRAD54 9.5
BCR protein 9.5
CSB 9.5
CAK 9.4
SLC30A9 9.4
more...
Disease
XPG/CS 13.4
Pigmented xerodermoid 13.4
Idiopathic photodermatosis 13.4
xeroderma pigmentosum 13.4
XPV 12.7
XP-A 12.7
trichothiodystrophy 12.7
Nevi and melanomas 12.4
physical developmental delay 12.4
Cockayne syndrome 12.0
XPE 12.0
XPG 11.9
Phylloid hypomelanosis 11.8
XPB 11.8
brittle hair 11.6
precancerous dermatosis 11.6
XPD 11.6
Photodermatosis 11.4
XPI 11.4
XPF 11.1
Haber's syndrome 10.8
solar skin damage 10.6
Xeroderma 10.5
neoplasm of the eye 10.4
Xeroderma pigmentosum group C 10.4
Chronic radiodermatitis 10.0
X-linked alpha-thalassemia/mental retardation syndrome 9.6
CSB 9.5
CSB 9.4
WWS 9.2
freckles 9.2
Fanconi syndrome 8.8
Bazex syndrome 8.7
Oral carcinoma 8.7
FANCJ 8.6
skin cancer 8.6
nevoid basal cell carcinoma syndrome 8.6
FUSE 8.6
RTS 8.5
XRN 8.5
inverted follicular keratosis 8.5
MSSE 8.5
poikiloderma 8.5
BLM 8.5
Atypical fibroxanthoma 8.4
hypoglobulinemia 8.4
dysplastic nevi 8.3
progeria 8.3
Ichthyosis vulgaris 8.2
ainhum 8.1
photosensitivity 8.1
Ophthalmomyiasis 8.0
epidermodysplasia verruciformis 7.9
Actinic cheilitis 7.9
Laugier-Hunziker syndrome 7.8
preneoplastic state 7.8
WRN 7.7
premature aging 7.7
Epidermal nevus syndrome 7.7
dyskeratosis congenita 7.6
eye cancer 7.5
Fanconi 7.4
nonmelanoma skin cancer 7.4
BGS 7.4
porokeratosis 7.4
nodular malignant melanoma 7.3
pellagra 7.3
ichthyosis 7.2
MEV 7.2
keratosis 7.1
basal cell carcinoma 7.1
squamous cell carcinoma of the skin 7.1
ichthyosis 7.1
Li-Fraumeni syndrome 7.0
pinguecula 7.0
environmental carcinogenesis 7.0
CSA 7.0
ATM 7.0
melanoma in situ 6.9
iris melanoma 6.9
more...
Symptom
hidroa 11.4
Inspiratory stridor 10.6
Cri du chat 10.6
prominent nose 7.0
scaly skin 7.0
photophobia 6.4
skin damage 6.0
athetosis 5.4
erythema 5.2
chorea 4.4
Decreased activity 4.4
stridor 4.2
ataxia 4.2
cerebellar ataxia 3.9
muscle cramps 3.6
cachexia 3.5
dysarthria 3.5
blepharospasm 3.4
spasticity 3.3
abnormal gait 3.3
ophthalmoplegia 2.7
dystonia 2.7
hypotonia 1.9
myoclonus 1.3
ENT 1.0
collapse 0.9
paresis 0.9
tremor 0.2
weakness 0.2
nausea and vomiting 0.2
Ill -0.0
starvation -0.2
sleepiness -0.2
stigma -0.3
exhaustion -0.3
anesthesia -0.5
vomiting -0.5
nausea -1.1
dyspnea -1.4
analgesia -1.4
seizures -1.9
fatigue -2.2
pain -3.0
Drug
Pyridoxamine phosphate 12.4
Anthramycin 9.1
Neocarzinostatin 7.6
Acitretin 7.2
Ara-A 6.6
Trabectedin 6.2
Dithranol 6.1
-deoxyadenosine 6.0
Gemzar 5.9
Tarceva 5.7
G418 5.6
Photofrin II 5.4
Imiquimod 5.4
BLM 5.3
Oxaliplatin 5.2
Mutagen 5.1
Amifostine 4.9
Tannic acid 4.8
AGG 4.8
caffeine 4.7
ZnCl2 4.6
ZnCl2 4.6
Fludarabine 4.5
Hypaque 4.3
Etoposide 4.3
Hypaque 4.1
Arsenic trioxide 4.1
Isotretinoin 4.0
Bortezomib 3.9
Erlotinib 3.9
GEO 3.8
TEL 3.8
Dermatol 3.6
AraC 3.4
Asn 3.4
Retinoic acid 3.3
TAT 3.2
Serum albumin 3.1
Vitamin B 3.1
TAC 2.8
PTC 2.6
ADR 2.4
MDS 2.3
Herceptin 2.3
pyridoxal phosphate 2.1
DNase I 2.0
ALA 2.0
nitroglycerin 1.9
IFN-beta 1.9
Vitamin A 1.8
ROS 1.8
MRC 1.7
niacin 1.5
THF 1.4
ABC 1.3
Adriamycin 1.2
Gel 1.1
Indomethacin 0.8
NH3 0.6
ENT 0.3
lysine 0.2
ascorbate -0.1
ampicillin -0.6
Monit -0.7
vitamin E -0.7
CSF -1.5
Enzyme
endonuclease V 9.4
AP lyase 8.5
ATase 8.1
deoxyribonuclease 7.9
PRE 7.4
PAT 7.1
Fpg protein 7.0
hypoxanthine-guanine phosphoribosyltransferase 6.4
endodeoxyribonuclease 6.3
DNA ligase 6.3
DNA ligase 6.3
endonuclease 6.3
endonuclease VII 5.7
DNA polymerase 5.7
chloramphenicol acetyltransferase 5.6
adenine phosphoribosyltransferase 5.0
transaldolase 4.8
3'-exonuclease 4.8
micrococcal nuclease 4.8
dihydrofolate reductase 4.7
DNase 4.7
CGT 4.6
factor D 4.6
interstitial collagenase 4.5
TGT 4.4
SPT 4.3
RNA polymerase 4.3
ADPase 4.3
topoisomerase 4.3
S1 nuclease 4.2
arylsulfatase A 4.1
factor C 4.1
topoisomerase 4.1
polynucleotide kinase 4.0
histone acetyltransferase 4.0
argininosuccinate synthetase 4.0
cdc2 4.0
ubiquitin-protein ligase 3.8
dihydropyrimidine dehydrogenase 3.8
SPT 3.6
TdT 3.5
ribonucleotide reductase 3.5
ribonucleotide reductase 3.4
adenosine deaminase 3.4
adenosine deaminase 3.4
methylenetetrahydrofolate reductase 3.4
methylenetetrahydrofolate reductase 3.4
PARP 3.3
TAT 3.2
thioredoxin reductase 3.1
dihydropyrimidine dehydrogenase 3.1
thymidine kinase 3.1
proteasome 3.1
beta-galactosidase 3.0
dopamine beta-hydroxylase 3.0
MAT 2.9
protein phosphatase 2A 2.8
PNGase F 2.8
deoxyribonuclease 2.8
apyrase 2.8
NQO1 2.8
catalase 2.8
MAT 2.6
PDE 2.6
MEKK1 2.6
proteinase K 2.4
APC 2.4
ornithine decarboxylase 2.4
phosphoglycerate kinase 2.3
ribonuclease 2.3
ribonuclease 2.3
glutathione S-transferase 2.1
peroxiredoxin 2.0
RNase 2.0
RNase H 2.0
calcineurin 1.9
luciferase 1.9
ATPase 1.9
RNase 1.9
CPT 1.8
more...
Compound
XPA 11.0
XPA 11.0
Soriatane 10.1
Pyridoxamine 5'-phosphate 10.0
Benzyl chloride 9.2
5-methylnicotinamide 9.0
8-Hydroxyguanine 8.5
Angelicin 8.0
Levobupivacaine 7.9
Psoralen 7.7
Novobiocin 7.7
Neocarzinostatin 7.7
Glycerophosphocholine 7.6
Aphidicolin 7.5
Aphidicolin 7.5
pyrimidine 7.3
pyrimidine 7.3
Phloroglucinol 7.3
PAT 7.3
1-pyrenol 7.2
4-NQO 7.2
alpha-Amanitin 7.2
Phloroglucinol 7.2
MEV 7.1
Mimosine 7.1
Mimosine 7.0
13-cis-Retinoic acid 7.0
SHB 6.8
methyl methanesulfonate 6.8
dUDP 6.5
AAF 6.4
NOP 6.4
6-Thioguanine 6.4
Selenate 6.3
Lomefloxacin 6.2
DBC 6.2
Dithranol 6.1
Etretinate 6.0
MNNG 5.9
Daunomycin 5.9
Benzo[a]pyrene 5.9
3-aminobenzamide 5.9
dUMP 5.7
phosphonoacetic acid 5.6
Acrolein 5.6
Ara-A 5.5
MOP 5.5
PBG 5.5
Ecdysone 5.4
PALA 5.4
m-AMSA 5.4
TTS 5.3
dGMP 5.3
5H-pyrido[4,3-b]indole 5.3
BLM 5.3
Nitrofurantoin 5.2
Bantu 5.2
Trp-P-2 5.2
Deoxyribonucleic acid 5.2
Arsenite 5.1
dCMP 5.1
Cyd 5.0
Sitosterol 5.0
MMC 5.0
DAMP 4.9
Ribose 4.9
Thymine 4.9
BUdR 4.9
EMS 4.9
Amifostine 4.9
Photofrin II 4.9
Pyridoxine 4.9
DNA 4.8
Hydroxyurea 4.8
pyrene 4.8
ENU 4.8
Ellagic acid 4.8
HN2 4.8
TGT 4.7
DDP 4.7
more...