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Pivot Concepts:
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Target Concepts:
Gene/Protein
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Query: UMLS:C0043346 (
xeroderma pigmentosum
)
2,924
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We describe a 25-year-old man with a primary cutaneous myxoid malignant melanoma and
xeroderma pigmentosum
. Histologically, the tumor had a lentiginous intraepidermal component and a dermal myxoid nodule containing fusiform cells with hyperchromatic nuclei and nuclear pseudoinclusions. Immunohistochemically, the tumor cells were positive for S-100 protein in both the epidermis and the dermis and did not stain with HMB-45, AE1-AE3,
MNF
116, antiactin, or anti-p53 protein. Although this tumor is rare, it should be considered in the differential diagnosis of cutaneous myxoid lesions.
...
PMID:Primary cutaneous myxoid melanoma: immunohistologic clues to a difficult diagnosis. 829 93