Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0043167 (pertussis)
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Human Gene/Protein
Galanin receptor 1 10.7
Guanine nucleotide-binding regulatory protein 10.1
EP3-V 9.7
Chemokine receptor-like 1 9.7
melatonin receptor Mel1a 9.7
cone transducin alpha subunit 9.7
ERI3 9.7
EP3-VI 9.7
Type II adenylyl cyclase 9.7
JTV1 9.7
FRP3 9.7
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 9.7
Galphaz 9.6
rhomboid domain containing 1 9.3
guanine nucleotide regulatory protein 9.1
RGS19 protein 9.1
ANKRD13C 9.1
adenylate cyclase-inhibiting 9.1
IL8R2 9.1
Receptor activity-modifying protein 2 9.1
CRAM-A 9.1
GLPE 9.1
PSP24 9.1
EDG-2 9.0
EDG-4 9.0
guanine nucleotide-binding regulatory protein 9.0
G protein-linked receptor 8.8
GPR20 8.7
pancreatic polypeptide receptor 8.7
SNSR4 8.7
P2Y14 8.6
AGS4 8.5
S1P5 8.5
guanine nucleotide-binding protein 8.5
G alpha q 8.5
adenylyl cyclase type V 8.4
Galpha14 8.4
DPT 8.4
GTP-binding protein 8.4
Gq class 8.4
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Disease
pertussis 10.7
Reactive mastocytosis 10.7
Bordetella 10.2
Bordetella infection 10.1
Acute ischaemic heart disease 9.7
Purulent bronchitis 9.1
diphtheria 8.9
IPV 8.5
AGS4 8.5
nonfilarial elephantiasis 8.3
tetanus 8.1
FHA 8.1
NEM2 8.1
HCA1 8.0
Acute cough 7.7
localized skin infection 7.5
polio 7.4
AGS3 7.2
mumps 7.2
Chlamydia psittaci pneumonia 7.1
Other infectious diseases 7.1
Leiner's disease 7.0
cholera 6.9
Haemophilus meningitis 6.9
scarlet fever 6.8
rubella 6.8
Peritoneal infection 6.8
measles 6.7
cross-dependence 6.6
pseudocroup 6.5
allergic arthritis 6.4
lymphocytosis 6.4
Recurrent respiratory tract infections 6.3
Salmonella enteritis 6.3
Neutrophil dysfunction 6.1
NIID 6.1
Haemophilus 6.1
Gianotti-Crosti syndrome 6.1
viral leukemogenesis 6.0
Campylobacter enteritis 6.0
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Symptom
Purulent nasal discharge 8.1
Local swelling 8.0
sinus pain 7.3
Moderate pain 6.6
Injection site pain 6.3
persistent cough 6.2
impaired motor coordination 5.7
rundown 5.2
cough 4.8
Grimace 4.6
chronic cough 4.2
nocturnal cough 3.8
cyanosis 3.6
non-productive cough 3.5
generalized rash 3.5
Severe pain 3.4
precordial pain 3.2
incoordination 3.2
peri-menopausal 3.2
catarrh 3.1
labored breathing 2.9
productive cough 2.9
Respiratory symptoms 2.8
Catch 2.7
postnasal drip 2.7
sneezing 2.6
ataxic gait 2.6
Fluctuation 2.4
prostration 2.1
Tenderness 2.1
vomiting 2.1
neurological disability 1.8
bitter taste 1.8
erythema 1.8
wheezing 1.8
hoarseness 1.7
pallor 1.7
arm pain 1.7
twitching 1.7
analgesia 1.6
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Drug
Pertussis vaccine 10.3
Sulfisomidine 9.1
Xaliproden 9.1
Adsorbed tetanus toxoid 8.3
Guanadrel 8.1
Diphtheria toxoid 7.4
CFTM-PI 7.3
Tetanus toxoid 7.0
Rokitamycin 7.0
Japanese encephalitis vaccine 6.9
Diphtheria antitoxin 6.9
Dexamethasone acetate 6.6
Smallpox vaccine 6.3
Cefuzonam 6.3
Sulprostone 6.3
Forskolin 6.2
Iodophenyl 6.1
Deferoxamine mesylate 6.1
CPDX-PR 6.0
Fluspirilene 6.0
OMP 5.9
Enprostil 5.7
Butaprost 5.7
Manganese chloride 5.7
Spiegel 5.6
Tiopronin 5.6
Minipress 5.6
Alphagan 5.5
Cefpiramide 5.5
Denopamine 5.5
CZX 5.5
CZON 5.4
Cefprozil 5.4
Arlacel 5.4
Stelazine 5.3
CMNX 5.3
Olomoucine 5.2
MgSO4 5.1
Platelet Activating Factor 5.1
Loracarbef 5.1
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Enzyme
ADP-ribosyltransferase 7.5
cytidylate cyclase 7.5
ADP-ribosyltransferase 7.5
adenylate cyclase 7.2
actinase E 7.2
phospholipase C 6.9
NAD glycohydrolase 6.9
EC 5.3.99.2 6.6
ADP-ribosylarginine hydrolase 6.4
PI-PLC 6.4
sphingosine kinase 6.4
GMT 6.2
UDP-N-acetylglucosamine acyltransferase 6.1
duodenase 6.0
phospholipase D 6.0
8-lipoxygenase 5.9
protein acyltransferase 5.8
GRK2 5.8
protein kinase C 5.7
cGMP phosphodiesterase 5.3
PAF acetyltransferase 5.3
cholesterol 25-hydroxylase 5.2
pyroglutamyl peptidase II 5.1
phospholipase A2 5.0
PTPase 5.0
PGE2 isomerase 5.0
ceramide kinase 4.9
GMP reductase 4.9
lysophospholipase D 4.9
phosphatidylinositol 3-kinase 4.9
phosphoinositide 5-phosphatase 4.8
phosphoinositide 3-kinase 4.8
dolichol kinase 4.7
diacylglycerol kinase 4.7
GRK5 4.7
serralysin 4.5
galactosyltransferase I 4.5
endo-alpha-N-acetylgalactosaminidase 4.5
Ins(1,4,5)P3 3-kinase 4.5
MEK 4.4
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Compound
17-hydroxyyohimban-16-carboxylic acid 10.7
DTP 9.3
LTB4-dimethylamide 9.1
6-chloronicotinamide 8.7
6-chloronicotinamide 8.7
20CF3-LTB4 8.7
C20H30O3 8.3
DPT 8.2
2-hydroxytetradecanoic acid 8.1
Guanadrel 8.1
piperidine oxalate 8.1
3-ethyl-1H-indole 7.9
5-isoquinolinesulfonic acid 7.9
8-Cyclopentyltheophylline 7.9
K-DR 7.9
3,4-D 7.6
Sulmazole 7.5
3-hydroxyhexadecanoic acid 7.4
2,5-pyrrolidinedione 7.3
LY 294002 7.3
Sphingosine 1-phosphate 7.2
Dexamethasone acetate 7.2
Inositol phosphate 7.2
1-amino-1,3-cyclopentanedicarboxylic acid 7.2
G11 7.2
2-(4-morpholinyl)ethyl 7.1
fMet 7.1
Muscarine 7.1
Himbacine 7.1
8-(diethylamino)octyl 3,4,5-trimethoxybenzoate 7.1
Polymyxin B sulfate 7.1
2-(4-morpholinyl)ethyl 7.0
S 10 7.0
1,3-benzenedisulfonic acid 7.0
1,3-benzenedisulfonic acid 7.0
1H-pyrrole-2,5-dione 6.9
2-amino-4-phosphonobutanoic acid 6.9
2-amino-4-phosphonobutanoic acid 6.9
1,3-cyclopentanedicarboxylic acid 6.9
Palmitoyl-L-carnitine 6.9
more...