Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0043167 (pertussis)
 19,595 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
GTP 1804
adenylate cyclase 1712
ADP 1636
Sep 1373
Mol 1143
adenylyl cyclase 926
AMP 872
ATP 698
GDP 527
insulin 520
GTP-binding protein 434
somatostatin 395
cytokine 371
tyrosine kinase 369
GTPase 367
calmodulin 309
ERK1 296
chemokine 288
lipopolysaccharide 288
opioid receptor 285
bradykinin 269
G protein-coupled receptor 269
PKC 268
thrombin 267
muscarinic receptor 245
phospholipase A2 232
phosphodiesterase 232
IgA 228
angiotensin II 225
guanine nucleotide-binding protein 224
ERK 220
p38 219
NAD 218
membrane protein 210
polypeptide 208
mitogen-activated protein 202
IgE 201
phosphatidylinositol 3-kinase 197
MAPK 193
membrane-bound 193
MAP kinase 185
CD4 181
extracellular signal-regulated kinase 176
epidermal growth factor 175
MEK 173
Rho 167
calcium channel 165
lymphoid 152
phospholipase D 150
PLC 148
p42 147
glucagon 146
adenosine receptor 145
vasopressin 141
GABA 138
protein kinase C inhibitor 133
G-protein-coupled receptor 132
SDS 131
substance P 129
IL-8 128
DPT 124
mast cell 122
neuropeptide Y 121
Ang II 121
p44 117
PKA 116
guanine nucleotide regulatory protein 116
LPS 115
5-hydroxytryptamine 114
beta 1 114
ADP-ribosyltransferase 114
guanine nucleotide binding protein 113
IFN-gamma 112
Met 112
phospholipase 111
IL-6 110
cannabinoid receptor 110
SRIF 110
cyclooxygenase 109
adenosine A1 receptor 108
Gen 107
endothelin-1 107
ATPase 106
tumor necrosis factor 106
nitric oxide synthase 104
CXCR4 104
endoplasmic reticulum 102
IAP 102
HEK 101
IFN 101
phosphoinositide 3-kinase 98
IL-4 97
CD11b 97
Pseudomonas 96
collagen 94
c-fos 93
CD8 92
CB1 92
PI3K 91
RANTES 89
TNF-alpha 88
vasoactive intestinal peptide 87
chemokine receptor 87
TNF 86
5-HT1A 85
RhoA 85
PRP 85
beta-endorphin 84
IL-10 84
prolactin 82
interferon 82
phosphatase 81
fused 78
cAMP-dependent protein kinase 78
CD18 77
fibronectin 75
IL-2 75
ET-1 75
glycoprotein 74
platelet-derived growth factor 71
H. influenzae 71
NAD+ 71
serum albumin 69
metabotropic glutamate receptor 68
lipoxygenase 68
galanin 68
FMLP 67
thymus 67
JNK 66
alpha, beta 66
P2Y2 66
calcitonin 65
rhodopsin 64
guanylate cyclase 64
CXCL12 63
arrestin 63
CCR5 63
MEK1 62
bombesin 62
TLR4 62
lectin 61
FPR1 61
ras 61
ERK2 60
parathyroid hormone 60
CB2 60
GMP 60
epidermal growth factor receptor 59
proximal tubule 59
IL-17 59
IL-5 58
formyl peptide receptor 58
albumin 57
P2X 57
vasoactive intestinal peptide (VIP) 57
AT1 56
GTP binding protein 56
oxytocin 56
TPA 55
myelin basic protein 55
more...
Disease
pertussis 19595
Bordetella 4390
tetanus 2151
diphtheria 2118
cholera 1479
measles 807
polio 698
Haemophilus 643
influenza 522
hepatitis B 503
infectious diseases 474
rubella 408
mumps 382
neuroblastoma 276
tuberculosis 224
tumor 223
varicella 222
pneumonia 217
cancer 205
glioma 192
encephalomyelitis 191
lymphocytosis 176
asthma 141
HIV 138
depression 135
IPV 134
respiratory infection 132
SDS 131
respiratory disease 130
multiple sclerosis 126
diabetes 114
hepatitis A 110
encephalopathy 104
Infection 96
leukemia 92
immunodeficiency 90
FHA 88
hypertension 87
fits 85
Mycobacterium 79
bronchitis 78
atherosclerosis 78
meningitis 77
Mycoplasma 76
anaphylaxis 73
cold 73
lymphoma 71
smallpox 67
melanoma 66
Alzheimer's disease 66
typhoid 62
astrocytoma 61
pheochromocytoma 60
encephalitis 60
malaria 59
heart failure 59
autoimmune disease 59
Legionella 59
carcinoma 58
ATM 57
Poland 56
Blocking 54
herpes zoster 54
ischemia 52
bronchitis 49
Chlamydia 49
virus infection 49
sepsis 47
West 46
bacterial infection 46
yellow fever 45
breast cancer 43
EPI 41
Brown 40
scarlet fever 40
Yersinia 39
hepatocellular carcinoma 39
anthrax 39
AIDS 39
rabies 38
cystic fibrosis 37
plaque 36
arthritis 36
malnutrition 35
pituitary tumor 35
MIP 34
SCH 34
SEM 33
pulmonary hypertension 33
epilepsy 31
sepsis 31
insulinoma 31
CTX 31
erythroleukemia 30
rheumatoid arthritis 30
IVA 30
eosinophilia 30
hyperglycemia 29
osteosarcoma 29
Japanese encephalitis 29
NAME 29
hepatitis 29
tumor growth 28
sudden infant death syndrome 28
bronchiolitis 27
Klebsiella 27
hypoglycemia 27
Infections 27
Pineal 27
stroke 27
MCF 26
respiratory failure 25
cytomegalovirus 25
PAF 24
uveitis 24
tonsillitis 24
idiopathic thrombocytopenic purpura 24
bronchopneumonia 23
Bordetella infection 23
uterus 23
otitis media 23
Adhesion 22
Spleen 22
metastases 21
ovarian cancer 21
pharyngitis 20
SMS 20
multiple myeloma 20
dengue 19
congestive heart failure 19
adenocarcinoma 19
Proteus 19
RGS 19
plague 19
Mycoplasma pneumoniae pneumonia 18
Evans 18
Shigella 18
autism 18
obesity 18
neurological disease 18
myocardial infarction 18
APC 18
Epstein 18
myocardial ischemia 17
addiction 17
prostate cancer 17
Ovary 17
Ovary 17
urinary tract infection 17
adenoma 16
vascular disease 16
Steroids 16
lung disease 16
human papilloma virus 16
herpes simplex 16
hepatitis C 16
cervical cancer 16
febrile convulsions 16
Schistosoma mansoni 16
gastroenteritis 16
more...
Symptom
cough 404
pain 188
seizures 109
vomiting 83
diarrhea 75
analgesia 52
starvation 30
collapse 30
cyanosis 29
respiratory distress 28
erythema 28
persistent cough 27
chronic cough 23
sleepiness 23
anorexia 18
hypothermia 17
anesthesia 16
tremor 11
dyspnea 11
rundown 11
headache 11
wheezing 10
incoordination 10
syncope 8
splenomegaly 8
discomfort 8
discomfort 8
sneezing 7
ataxia 7
flushing 7
impaired motor coordination 6
hoarseness 6
pallor 5
agitation 5
productive cough 5
acute stress 5
fatigue 5
sore throat 5
hemoptysis 5
hypercapnia 5
tachypnea 4
twitching 4
hypotonia 4
weakness 4
stridor 4
cerebellar ataxia 4
chest pain 3
HSA 3
exertional dyspnea 3
rhinorrhea 3
sinus pain 3
angina 3
Ill 3
bitter taste 3
myalgia 3
functional recovery 3
lethargy 3
spasticity 3
paraparesis 2
tense 2
Neuropathic pain 2
nasal discharge 2
Local swelling 2
constipation 2
neurological disability 2
Fluctuation 2
nausea 2
polyuria 2
cachexia 2
exhaustion 2
Respiratory symptoms 2
decreased appetite 2
chills 2
Catch 2
non-productive cough 2
ataxic gait 2
abdominal pain 2
pelvic pain 1
rigors 1
pleuritic chest pain 1
Welt 1
arm pain 1
Grimace 1
spasm 1
nocturnal cough 1
myoclonus 1
general problem 1
Purulent nasal discharge 1
postnasal drip 1
Stiffness 1
labored breathing 1
dystonia 1
Moderate pain 1
muscle rigidity 1
abnormal gait 1
Severe pain 1
acidity 1
rales 1
stigma 1
generalized rash 1
precordial pain 1
dry eye 1
prostration 1
sciatica 1
hemiplegia 1
hyperoxia 1
hip pain 1
nausea and vomiting 1
acute pain 1
hunger 1
skin damage 1
overweight 1
Injection site pain 1
Tenderness 1
leg pain 1
shortness of breath 1
catarrh 1
catatonia 1
ENT 1
peri-menopausal 1
polydipsia 1
Drug
Forskolin 121
IFN-gamma 106
caffeine 84
Histamine 84
Angiotensin II 83
MAP 75
IL-2 75
ICI 73
lysine 68
Nephron 68
CSF 62
CTX 53
ETA 48
Cardiovasc 46
PTH 42
Pertussis vaccine 42
EPI 41
Clonidine 40
Dermatol 38
Gel 34
MgSO4 33
CTX 31
CTX 31
ROS 29
Atropine 27
ampicillin 27
Glucagon 21
Ethanol 20
ACT 19
Asn 19
BCG vaccine 18
9-THC 18
OMP 17
lactose 17
CaCl2 16
Indomethacin 16
CaCl2 16
CaCl2 16
DNase I 16
-deoxyadenosine 15
Tetanus toxoid 14
Alliance 14
niacin 14
Asthma 13
EE2 10
GRF 10
Vitamin A 8
Fraction 7
uPA 7
NADH 7
Retinoic acid 7
Spiegel 7
CAM 7
Trifluoperazine 7
PCP 7
Fentanyl 6
Azithromycin 6
Amiloride 6
Amiloride 6
Sulprostone 6
Meth 6
Sodium nitroprusside 6
Iloprost 6
G-CSF 5
AC2 5
Sulpiride 5
Theophylline 5
AMC 5
NAG 5
HCH 5
nitroglycerin 5
Japanese encephalitis vaccine 5
Secretin 5
MRC 5
CCL 5
vitamin E 5
ENT 5
Salbutamol 5
Growth hormone 4
FAD 4
Fragment 4
Monit 4
Aprotinin 4
DHT 4
TMS 4
Leaf 4
Growth hormone 4
Nephron 4
Phentolamine 4
DHT 4
ROC 4
Rokitamycin 4
ascorbate 4
Rolipram 4
TAT 4
ABC 4
LCM 3
LCM 3
citric acid 3
Adenosine deaminase 3
IL-1ra 3
p75 3
Prednisolone 3
PMEA 3
Portal 3
Misoprostol 3
Diphtheria toxoid 3
Apomorphine 3
Activin 3
Fluorescein 3
IL-11 3
Rimonabant 3
balanced salt solution 3
Dial 3
CTA 3
Adenosine triphosphate 3
AraC 3
pyridoxal phosphate 3
Kenyan 3
Methylene blue 3
Fluorescein 3
Simvastatin 3
APD 3
GNA 2
CTC 2
Emodin 2
Alanine 2
Phenytoin 2
Glutathione 2
Glycerol 2
CVA 2
CPZ 2
Amoxicillin 2
Engerix-B 2
Enprostil 2
Emodin 2
Prozac 2
Urokinase 2
CTRX 2
Tiopronin 2
Vitamin B 2
GHRP 2
Monensin 2
Diphenhydramine 2
Magnesium sulfate 2
Diphtheria antitoxin 2
Maalox 2
Gabapentin 2
TAK 2
Ceftazidime 2
K-252a 2
CFTM-PI 2
CEC 2
Heme 2
Scopolamine 2
KAN 2
Butaprost 2
NVP 2
Riboflavin 2
Luteinizing 2
more...
Enzyme
adenylate cyclase 1771
protein kinase C 1576
phospholipase C 1399
mitogen-activated protein kinase 994
protein kinase 867
phospholipase A2 290
ERK 278
thrombin 263
MEK 243
phosphodiesterase 234
phosphatidylinositol 3-kinase 197
phospholipase D 150
ATPase 128
PARP 117
ADP-ribosyltransferase 114
ADP-ribosyltransferase 114
phosphoinositide 3-kinase 98
guanylate cyclase 93
trypsin 93
focal adhesion kinase 85
AMPK 84
calcineurin 75
NADPH oxidase 69
NADPH oxidase 69
lipoxygenase 68
luciferase 64
NO synthase 62
reverse transcriptase 55
alkaline phosphatase 53
RNA polymerase 51
MAP 50
adenosine deaminase 49
adenosine deaminase 49
caspase-3 47
peroxidase 39
sphingosine kinase 38
collagenase 38
lysozyme 37
superoxide dismutase 36
MIP 34
NAD glycohydrolase 32
lactate dehydrogenase 32
catalase 30
PI-PLC 30
CaMKII 29
neuraminidase 29
GRK2 29
transcriptase 28
PKG 27
urokinase-type plasminogen activator 26
renin 25
glutathione S-transferase 25
GSK 24
cGMP phosphodiesterase 24
APC 22
PDE 22
hexosaminidase 21
PTPase 20
CPT 19
CPT 19
CPT 19
RNase 18
plasmin 18
chymotrypsin 18
lipoprotein lipase 18
GRK5 18
myosin light chain kinase 18
proteasome 18
beta-galactosidase 17
RNase 17
alanine aminotransferase 17
diacylglycerol kinase 16
phosphorylase 16
NOS 15
acetylcholinesterase 15
GMT 15
elastase 14
apyrase 13
beta-glucuronidase 13
tyrosine hydroxylase 13
triphosphatase 13
beta-lactamase 13
protein phosphatase 2A 12
ACE 12
endonuclease 11
proteinase K 10
aequorin 9
AMP-activated protein kinase 9
N-acetyltransferase 9
lipase 9
caspase-1 9
creatine kinase 9
MEKK1 9
ornithine decarboxylase 8
deaminase 8
5'-nucleotidase 8
SPC 8
IKK 8
chloramphenicol acetyltransferase 8
histidine decarboxylase 7
MMP 7
urease 7
tissue plasminogen activator 7
xanthine oxidase 7
cdc2 7
monoamine oxidase 7
PCP 7
CD10 7
urease 7
chymase 6
ACS 6
firefly luciferase 6
kallikrein 6
acid phosphatase 6
12-lipoxygenase 6
hyaluronidase 6
AMPK 6
sialidase 6
CDR 6
tryptase 6
prostaglandin synthetase 6
phosphoenolpyruvate carboxykinase 5
ribonuclease 5
phosphoenolpyruvate carboxykinase 5
ribonuclease 5
ricin 5
p-nitrophenylphosphatase 5
histidine kinase 5
caspase-9 5
pepsin 5
phosphoenolpyruvate carboxykinase 5
subtilisin 5
glyceraldehyde-3-phosphate dehydrogenase 5
alpha-amylase 5
choline acetyltransferase 5
pyruvate kinase 5
MDP 5
glyceraldehyde-3-phosphate dehydrogenase 4
neutrophil elastase 4
NADPH-diaphorase 4
15-lipoxygenase 4
transglutaminase 4
glycerol-3-phosphate dehydrogenase 4
cathepsin G 4
HtrA 4
glutamine synthetase 4
hyaluronidase 4
MDR 4
glutathione peroxidase 4
neuropathy target esterase 4
SPT 4
glyceraldehyde-3-phosphate dehydrogenase 4
carboxypeptidase Y 4
glycerol-3-phosphate dehydrogenase 4
PDK1 4
hormone-sensitive lipase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
lysophospholipase D 4
ceramidase 4
more...
Compound
calcium 3490
cAMP 2036
GTP 1810
ADP 1698
ADP 1639
ADP 1636
Dec 1426
AMP 969
phosphate 881
Clin 849
DNA 815
ATP 701
acetate 661
sodium 655
tyrosine 551
GDP 543
Phe 403
potassium 311
glucose 292
arginine 290
NAD 283
glutamate 272
leucine 260
noradrenaline 259
cGMP 235
NAD 218
nitric oxide 212
DTP 181
sulfate 178
5-HT 177
water 171
Mg2+ 161
oxygen 157
UTP 154
methionine 152
prostaglandin E1 151
Adenosine 149
MEK 146
lysine 144
GABA 143
GABA 141
SDS 139
BCG 135
PMA 135
PMA 135
COS 127
ACh 126
aluminum 126
DPT 124
Gly 123
serine 122
Forskolin 121
PGE2 116
alanine 110
cysteine 109
threonine 107
Carbachol 103
fMet 101
ADP-ribose 90
Angiotensin II 88
salt 87
iron 87
manganese 86
TNF 86
caffeine 84
NH2 84
Histamine 84
Thrombin 82
cyclopentyl 82
Dopamine 82
GMP 82
prostacyclin 81
glycerol 79
nicotinic acid 77
hydroxide 75
Guo 75
Guo 74
Melatonin 73
ICI 73
nicotinic acid 72
Asp 72
Isoproterenol 71
ethanol 70
PGE 70
Insulin 68
FMLP 67
nicotinic acid 66
nicotinic acid 66
Cardiol 65
DAMGO 64
gamma-aminobutyric acid 64
adenylate 63
urea 63
bromide 62
ammonium 61
Norepinephrine 61
His 59
Bradykinin 59
nickel 58
Ins(1,4,5)P3 58
UDP 58
formaldehyde 57
TPA 55
hydrogen 55
TPA 55
nicotinamide 54
CTX 53
THP 52
uridine 52
THP 52
Sphingosine 51
Guanine 51
formaldehyde 50
Adrenal 50
MAP 50
TSH 50
galactose 50
ETA 49
Ang II 49
cadmium 48
Sphingosine 1-phosphate 47
ACTH 47
Triton X-100 47
Phorbol 45
G11 43
Staurosporine 42
Staurosporine 42
retinoic acid 42
pyrimidine 41
Baclofen 41
pyrimidine 41
aldosterone 40
tryptophan 39
DAMP 38
TRH 37
H2O2 37
DAMP 37
cobalt 37
NMDA 36
dicarboxylic acid 36
barium 36
TMB 36
PAC 35
D-Ala 34
AMPA 34
2-methylpiperazine 34
4-chlorophenyl 33
PLA 33
PEG 33
4-chlorophenyl 33
Arachidonic acid 33
EDTA 32
EDTA 32
Ile 32
zinc 32
dipropyl 31
nitrogen 31
Erythromycin 30
MDA 29
MgCl2 29
more...