Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0043167 (pertussis)
 19,595 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cefsulodin (12 mg/l) was evaluated as an alternative to cephalexin (40 mg/l) as selective agent in agar for isolation of Bordetella pertussis from clinical specimens. Charcoal horse blood agar with cefsulodin and with cephalexin supported growth of Bordetella pertussis strains (n = 50) equally well. The nasopharyngeal flora of healthy adults (n = 49) was suppressed significantly better by cephalexin, but colony numbers of flora on the agar with cefsulodin in general were low.
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PMID:[Comparison of cefsulodin and cephalexin as selective agents in agar for Bordetella pertussis]. 235 8

Sprague Dawley (SD) rats were immunized with various cephalosporin- and penicillin-ovalbumin (OvA) in combination with aluminium hydroxide (alum) and thimerosal-killed Bordetella pertussis. Anti-cephalosporin IgE antibody production was inferior to anti-penicillin IgE antibody production. Cefsulodin (CFS), sulbenicillin (SBPC) and alpha-sulfophenyl acetic acid (SPAA) cross-reacted with each other but did not react with cephaloridine (CER), cefazolin (CEZ) and penicillin G (PCG). CER and PCG slightly cross-reacted with each other but did not cross-react with the others tested. Anti-CFS and anti-SBPC IgE sera were related specifically to the SPAA moiety.
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PMID:IgE antibodies for penicillins and cephalosporins in rats. III. Antigenic specificity of rat anti-cephalosporin-OvA IgE sera. 616 4