Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0043167 (
pertussis
)
19,595
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Thiamine plays a critical role in energy metabolism. Critically ill children and adults may develop
thiamine deficiency
with ultimately increased mortality due to potentially irreversible consequences of severe type B lactic acidosis. We report a case of an unvaccinated term neonate with malignant
pertussis
requiring extracorporeal membrane oxygenation and continuous renal replacement therapy, who developed profound lactic acidosis of unknown etiology. After countless evaluations for likely causes, the patient was ultimately determined to have
thiamine deficiency
and her acidosis resolved rapidly with vitamin supplementation.
...
PMID:Thiamine Deficiency Leading to Refractory Lactic Acidosis in a Pediatric Patient. 2911 26
