Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0043167 (pertussis)
19,595 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Reemergence of pertussis in a form of epidemic was observed in Poland in 1997/1998. Since that time we observe rather sustained trend of increased incidence and shift in the age of infected to the older age groups. 2954 cases were reported in 2004, an increase from the previous year (2034 in 2003) More cases occurred among females (1668 cases, 8.5/100,000) than among males (1286 cases, 7.0/ 100,000) and in urban areas 2258 (9.6/100,000) than in the rural ones 696 (4.7/100,000). Big differences in numbers of cases reported between different districts and between urban and rural areas bring strong possibility of insufficient sensitivity of the surveillance in many regions of Poland. Since in most cases diagnosis was based on serological tests, assessment or the fraction of parapertussis cases is impossible. It remains obscure to what extend recurrence of pertussis depends solely on the shift of incidence to older ages, to the decrease of vaccine efficiency or to the independent increase of parapertussis.
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PMID:[Pertussis in Poland in 2004]. 1724 61

Clinical isolates of Bordetella pertussis collected during the year 2004 (n = 153) in eight European countries, Denmark, Finland, France, Germany, The Netherlands, Poland, Sweden, and United Kingdom, were analyzed by pulsed-field gel electrophoresis (PFGE), and their PFGE profiles were compared with those of isolates collected in 1999 (n = 102). The 255 isolates produced 59 distinct PFGE profiles. Among the 153 isolates from 2004, 36 profiles were found, while within the 102 isolates from 1999, 33 profiles were detected. One PFGE profile, BpSR11, was dominant (30% to 50%) in all countries except Denmark (10%) and Poland (0%). In comparison with 1999, there was an increase in BpSR11 prevalence in Finland in 2004 from 5% to 40%, coinciding with a major incidence peak. Some other PFGE profiles seemed to be associated with limited dissemination. Poland was the only country in which the most common actual European PFGE profiles were not found. In a dendrogram analysis, all common PFGE profiles were identified within PFGE group IV, and BpSR11 clustered together with PFGE subgroup IVbeta. Compared to the 1999 isolates, PFGE group V representative for pertactin variant prn3 strains had disappeared, and a new cluster was seen. In conclusion, some PFGE profiles, such as BpSR11, evidently have a higher capacity to spread, suggesting increased fitness to the present immunological environment. It is therefore of major interest to continue with surveillance programs of B. pertussis isolates, as both waning vaccine-derived immunity and strain variation may play a role in the persistence of pertussis.
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PMID:Bordetella pertussis strains circulating in Europe in 1999 to 2004 as determined by pulsed-field gel electrophoresis. 1769 46

In 2005 number of reported cases of pertussis in Poland was 1925, 35% les then in the previous year (2954 in 2004). More cases occurred among females (1084 cases, 5.5 /100,000) than among males (841 cases, 4.6 /100,000) and in urban areas 1447 (6.2 /100,000) than in the rural ones 478 (3.2 /100,000). But in younger age groups 0-4 and 5-9 higher incidence was observed in rural areas. The difference was particularly big among children les than 1 year. In general number of cases reported in Poland remains relatively low. Problem is uneven distribution in different voivodeships (districts) which bring strong possibility of very low sensitivity of surveillance between regions.
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PMID:[Pertussis in 2005]. 1795 34

Pertussis epidemiology was examined in selected Central and Eastern European countries andTurkey (CEEs) from 1945 to 2005. Epidemiology and immunisation coverage data were collected fromNational Health Departments and Epidemiology Institutes. Pertussis diagnosis was made by the World Health Organization (WHO) clinical criteria, laboratory confirmation and/or epidemiological link, except for Romania (WHO clinical case definition used). In the pre-vaccine era, pertussis incidence (except Turkey) exceeded 200/100,000 (range180-651/100,000), with 60-70% of cases occurring in pre-school children. Until 2007, a second-year booster was givenin Estonia, Lithuania and Turkey, and an additional pre-school booster elsewhere. During 1995-2005, immunisation coverage by the age of 2 years exceeded 80% (range 80-98%) and, excluding Estonia, pertussis incidence was <3/100,000. Age-specific incidence rates rose in 5-14 year olds in Poland, Estonia and the Czech Republic. Incidence rates in children <1 year of age remained unchanged. There were two age distribution patterns. In the Czech Republic and Estonia, 16% of cases occurred in pre-school children and 17% and 22% in children >15 years of age, respectively; in Romania, Turkey and Lithuania, 51%, 71% and 73%, respectively, occurred in pre-school children and <7% in children aged >15 years.Pertussis infection persists, despite high immunisation coverage. Compared with the pre-vaccine era, the age distribution changed differentially in CEEs, with an apparent shift towards older children.
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PMID:Epidemiological characteristics of pertussis in Estonia, Lithuania, Romania, the Czech Republic, Poland and Turkey-1945 to 2005. 1860 58

In 2006 number of reported cases of pertussis in Poland was 1520, 21% less then in the previous year (1925 in 2005). Slightly higher incidence was among females (846 cases, 4,3/100 000) than among males (674 cases, 3,7/100 000). In urban areas incidence was significantly higher 1185 cases (5,1/100 000) than in the rural ones 335 (2,3/100 000). Incidence in urban areas was higher in all age groups. In general number of cases reported in Poland remains relatively low. Problem is uneven distribution in different voivodeships (districts) which bring strong possibility of very low sensitivity of surveillance in some regions.
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PMID:[Pertussis in 2006]. 1880 64

The article presents comparative study of the incidence of adverse effects following vaccinations with whole cell and acellular pertussis vaccines, based on data collected in obligatory routine surveillance of AEFI in the period of 2001-2005 in Poland. Comparisons done in children less then 2-years-old show in general about twice as high incidence of adverse effects following the whole-cell than the acellular vaccine. The biggest rate of proportions (RR = 4,75) was observed for high pitch cry. There was no significant difference in incidence of the most severe reactions, including encephalopathy and nonfebrile seizures, and there was no significant difference in allergic reactions.
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PMID:Comparison of adverse effects following immunization with vaccine containing whole-cell vs. acellular pertussis components. 1910 23

The fact that incidence of infectious diseases in Poland is quite stable and, as compared with many noninfectious diseases relatively better, should not lead to underestimation of the problem. Despite in many diseases long term trends indicate decreasing incidence, in some important diseases increase of incidence was noted. Significant decrease was noted in incidence of some diseases for which vaccination program was modified. It concerns mumps, Hib infections, and to some extend also pertussis. Serious problem remains with accumulated through several years high prevalence of hepatitis B and C. Also low vaccine coverage of influenza is a measure of weakness of prevention against this disease, which is one of the most important causes of job and school absence and despite low mortality, is one of important caused of increased mortality in winter season. Next important epidemiological problem cause bacterial and viral foodborne infections, which despite some improvement place Poland below average of EU. Also relative stabilization of the incidence of tuberculosis does not look good if compared with leading countries of EU. With HIV infections particular concern is brought by the number of late diagnoses and drastic decline of data on the probable risk factor of infection. Infectious diseases mortality in 2007 was 6.6/100,000 (3.5 in Podlaskie Voivodeship and 9.3 in Slaskie) and it was higher in cities (7.1) then in rural areas. As in previous years i man mortality (8.6) was higher then in women (4.9). Highest mortality from infectious diseases was noted among elderly people above 74 (30.6).
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PMID:[Infectious diseases in Poland in 2007]. 1979 37

In 2007 number of reported cases of pertussis in Poland was 1987 (5.2/100,000), 31% more then in the previous year (1520 in 2006). Higher incidence was among females (1109 cases, 5.6/100,000) than among males (878 cases, 4.8/100,000). In urban areas incidence was significantly higher (1448 cases 6.2/100,000) than in the rural ones (539 cases 3.7/100,000). Incidence in urban areas was higher in all age groups. In general number of cases reported in Poland remains relatively low. Problem is uneven distribution in different voivodeships (districts) which bring strong possibility of very low sensitivity of surveillance in some regions.
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PMID:[Pertussis in Poland in 2007]. 1979 43

In 2008, 2 163 cases of pertussis were reported in Poland. The incidence 5.7 per 100 000 was higher, 9% more compared to the last year (5.2). Highest incidence 37.7 per 100 000 population was observed in 10 - 14 age group and among urban areas population in all age groups. Of 2163 cases 870 (40%) were hospitalized. In 2008 one death attributed to pertussis was reported.
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PMID:[Pertussis in Poland in 2008]. 2073 Dec 18

We compared the 2.653 results of routine serological investigations performed in three different laboratories in Poland for the diagnosis of pertussis. One of the laboratories used the NovaLisa Bordetella pertussis kit produced by NovaTec GmbH and the two others used Bordetella pertussis ELISA kit produced by Genzyme Virotech GmbH. In first laboratory the diagnostic level of IgA antibodies to the pertussis toxin was observed in 11.0%, IgG in 52.7% and IgM in 27.4% serum samples. In the second and third laboratory the diagnostic level of IgA antibodies were found respectively in 22.2% and 40.1%, IgG in 46.8% and 66.4% and IgM only in 8.7% and 4.8% serum samples. In total, IgA antibodies were found in 28.0%, IgG antibodies in 56.0% and IgM antibodies in 14.3% serum samples obtained from patients suspected in clinical investigation for pertussis. We have observed that the frequency of detection of the antibodies in children and adolescents increased with age reaching its peak among individuals with age range between 11-20 years. We also found statistical significant higher frequency of IgA, IgG and IgM antibodies to B. pertussis in outpatients than in hospital patients.
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PMID:[Comparison of routine serological investigations performed in three different laboratories in Poland for the diagnosis of pertussis]. 2087 83


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