Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0043167 (pertussis)
 19,595 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Between February and April 1995, 669 under-five children living in Jimma town were randomly selected and had their nutritional status assessed. Risk factors for protein-energy malnutrition (PEM) were also studied. About half (48%) of the children were found to be malnourished. The prevalence of underweight, wasting and stunting were 36%, 9% and 36%, respectively. Severe protein-energy malnutrition, i.e., marasmus, kwashiorkor and marasmic-kwashiorkor, was detected in 2%. The prevalence of malnutrition was lowest in infants. While underweight and wasting peaked by the second and third years of life, stunting increased dramatically by the second year and peaked in the fifth year. Poor socio-economic background, poor housing condition, non-availability of latrine, "unprotected" water source, an attack of pertussis, not completing immunization, prolonged breast feeding and nutritionally inadequate diet were found to be risk factors for PEM in the bivariate analyses. Multiple logistic regression analyses showed a strong association between PEM and poor housing condition, non-availability of latrine, prolonged breast feeding and diet lacking in animal food. Intervention measures should take the multifactorial causation of PEM into consideration.
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PMID:Protein-energy malnutrition in urban children: prevalence and determinants. 1021 56

Leucocyte Migration Inhibition Factor (L-MIF) was measured in 41 children with marasmus, 19 with kwashiorkor, 5 with marasmic-kwashiorkor and 35 well-fed healthy children serving as controls. For L-MIF assay, two different antigens (live attenuated measles virus vaccine and diptheria pertussis tetanus (DPT) vaccine were used. Percentage migration indices obtained with the two antigens were significantly higher in the malnourished than in the well-fed healthy sex and age-matched controls (P < 0.01). The total serum protein and albumin concentrations were significantly reduced in the malnourished children compared with the controls (P < 0.01). Mean total leucocyte numbers were not significantly different in marasmic and marasmic-kwashiorkor children compared with the controls (P > 0.21).
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PMID:Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children. 1295 81